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Senior Python Engineer Jobs in Berkeley, CA (NOW HIRING)

Fuku

Senior/Staff Engineer

San Francisco, CA · On-site

$200K - $280K/yr

Senior/Staff Engineer Location: San Francisco, CA or New York, NY Compensation: $200,000 - $280,000 ... React - Backend: Python - Infrastructure: AWS, ECS - Tools: GitHub, Linear, Slack, Notion ...

Fuku

Senior/Staff Engineer

San Francisco, CA · On-site

$200K - $280K/yr

Senior/Staff Engineer Location: San Francisco, CA or New York, NY Compensation: $200,000 - $280,000 ... B ackend: Python * I nfrastructure: AWS, ECS * T ools: GitHub, Linear, Slack, Notion ...

Alamar Biosciences

Senior AI & Data Engineer

Fremont, CA

$134K - $176K/yr

We are looking for a Senior AI & Data Engineer to join our AI team. This is a hands-on individual ... Write clean, testable SQL and Python for data transformation, enrichment, and delivery to ...

Walmart

Senior, Software Engineer - Python

San Mateo, CA · On-site

$117K - $234K/yr

As a Senior Software Engineer at Walmart, you will lead the design, development, and delivery of ... Python. * Experience with continuous integration and continuous delivery (CI/CD) pipelines ...

Walmart

Senior, Software Engineer - Python

Hayward, CA · On-site

$117K - $234K/yr

As a Senior Software Engineer at Walmart, you will lead the design, development, and delivery of ... Python. * Experience with continuous integration and continuous delivery (CI/CD) pipelines ...

Planted Solar

Sr. Mechatronics Engineer

Oakland, CA · On-site

$110K - $175K/yr

Senior Mechatronics Engineer Oakland, CA Full-time First, the good news: The world now has over 1.7 ... Experience with Python programming for ROS2 nodes. * Experience with TwinCAT and CODESYS.

New

h2o.ai

Senior AI Engineer

San Francisco, CA · On-site

$180 - $280/hr

Lead end‑to‑end technical engagement with enterprise customers, acting as the senior point of ... Strong Python engineering skills; experience with ML frameworks (PyTorch, TensorFlow ...

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All JobsPython Engineer JobsSenior Python Engineer JobsSenior Python Engineer Jobs in Berkeley, CA

Senior Python Engineer information

See Berkeley, CA salary details

$67.3K

$173.8K

$238.8K

How much do senior python engineer jobs pay per year?

As of Aug 15, 2026, the average yearly pay for senior python engineer in Berkeley, CA is $173,840.00, according to ZipRecruiter salary data. Most workers in this role earn between $148,800.00 and $200,200.00 per year, depending on experience, location, and employer.

Are senior Python engineers in demand?

Senior Python engineers are highly in demand due to the language's widespread use in web development, data analysis, machine learning, and automation. Companies seek experienced developers with strong problem-solving skills and knowledge of frameworks like Django or Flask, making this a competitive and growing field.

What are the key skills and qualifications needed to thrive as a senior Python engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a senior Python engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges senior Python engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.

What job categories do people searching Senior Python Engineer jobs in Berkeley, CA look for?

The top searched job categories for Senior Python Engineer jobs in Berkeley, CA are:

What cities near Berkeley, CA are hiring for Senior Python Engineer jobs?

Cities near Berkeley, CA with the most Senior Python Engineer job openings:

Senior Python Engineer jobs near you
Infographic showing various Senior Python Engineer job openings in Berkeley, CA as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $173,840 per year, or $83.6 per hour.

Senior Embedded Software Engineer - Contract

Cytovale, Inc

South San Francisco, CA • On-site, Remote

$148K - $195K/yr

Temporary

Re-posted 5 days ago

Job description

Senior Embedded Software Engineer - Contract
Cytovale | Software & Data Systems
Department: Software & Data Systems
Reports To: Senior Engineering Manager, Software & Data
About Cytovale
Cytovale is a medical diagnostics company whose FDA-cleared IntelliSep® test enables rapid sepsis risk assessment in the emergency department. Our instrument combines microfluidic sample preparation, high-speed imaging, real-time image analysis, and advanced software to deliver clinically actionable results in minutes. We develop and maintain this technology under a regulated quality system compliant with FDA design controls, IEC 62304, ISO 13485, and modern cybersecurity expectations.
The Role
We are seeking a hands-on Senior Embedded Software Engineer to work on a contractual basis, contributing across the IntelliSep software platform, including the Sample Preparation Module (SPM), Cell Imaging Module (CIM), and Image Analysis Module (IAM). You will go beyond traditional embedded development by supporting Linux-based embedded platforms, software architecture, OS upgrades, and development infrastructure.
What You'll Do
  • Design, implement, and maintain embedded software in modern C++ across IntelliSep instrument platforms and Linux-based systems.
  • Support platform modernization efforts, including embedded OS upgrades, toolchain updates, and software infrastructure improvements.
  • Develop Python-based tools, build systems, and CI/CD pipelines to support verification and validation (V&V), manufacturing, service, and data workflows.
  • Troubleshoot complex issues spanning software, firmware, operating systems, networking, and instrument hardware.
  • Design and maintain interfaces between instrument subsystems, including imaging, motion control, sensing, and software services.
  • Author and maintain software requirements, architecture/design specifications, and quality system lifecycle artifacts.
  • Contribute to software V&V, cybersecurity maintenance, vulnerability remediation, risk management, and secure product development activities.
  • Distribute engineering knowledge through documentation, architecture reviews, and mentorship.

Required Qualifications
  • BS or MS in Computer Engineering, Electrical Engineering, Computer Science, or equivalent industry experience.
  • 8+ years of experience developing embedded software for complex electromechanical systems.
  • Expert-level C++ programming on Linux-based systems, with strong multi-threading and performance-optimization experience.
  • Experience integrating and debugging complex instrumentation (motion control, imaging, sensors, networking) using equipment like oscilloscopes and logic analyzers.
  • Strong Python programming skills.
  • Experience developing and maintaining CI/CD infrastructure, cross-compilation environments, and automated verification workflows.
  • Experience authoring software requirements, architecture documents, and design specifications.
  • Demonstrated ability to independently troubleshoot cross-disciplinary issues with excellent written and verbal communication skills.

Preferred Qualifications
  • Experience developing medical device software under FDA design controls, IEC 62304, ISO 13485, and risk management frameworks.
  • Hands-on embedded Linux experience, including OS interfaces, deployment, debugging, and lifecycle maintenance.
  • Experience with Docker, containerized build environments, and infrastructure automation.
  • Experience with distributed embedded systems architecture, configuration management, and regulated development processes.
  • Experience supporting cybersecurity deliverables (SBOM generation, vulnerability management, penetration testing remediation).
  • Experience with image acquisition, computer vision, image processing, or scientific instrumentation.

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