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Senior Python Engineer Jobs in Massachusetts (NOW HIRING)

Senior Software Engineer

Woburn, MA · On-site +1

$134K - $184K/yr

STR is hiring a Senior Software Engineer to be part of a multi-disciplinary team that transforms ... Implement real-time systems in C/C++ and Python from verified algorithms written in higher-level ...

Senior DevOps Engineer

Cambridge, MA · Remote

$143.20K - $184K/yr

... ENGINEER We are seeking a Senior DevOps Engineer to implement and manage our cloud based ... Python, bash, other scripting language experience is required. Ansible, Terraform, or equivalent ...

Senior Systems Engineer

Tewksbury, MA

$112.60K - $154.10K/yr

Senior Systems Engineer - LTAMDS Radar Work Location: On-Site Position Overview Looking for a ... Experience with C++, Python, or similar. * Experience with generating technical documentation, such ...

Senior Software Engineer

Waltham, MA · Hybrid

$132.20K - $174.20K/yr

Xometry is seeking a Senior Software Engineer to join our software engineering organization. In ... Reading, writing, and reviewing code written in HTML, Typescript/Javascript/React, Python, and Rust

Senior NLP Engineer

Boston, MA · On-site

$113.90K - $156.40K/yr

Senior Natural Language Processing (NLP) Engineer Would you like to contribute creatively to a ... Linux, Python, Bash, SQL, JavaScript * Excellent organizational and communication skills What's in ...

AI Engineer Location: Boston, MA - 4 days/week onsite-locals only with DL copy Pay rate: Senior ... The ideal candidate has strong experience with a modern AI/ML stack, including a profound Python ...

Senior Software Engineer

Boston, MA · On-site

$133.10K - $175.50K/yr

Senior Software Engineer Reports to: Sr. Manager, Software Engineering Location: Houston, TX; ... Advanced proficiency in Python, FastAPI, PyTest, Celery, and other Python frameworks * Deep ...

Senior DevSecOps Engineer

Boston, MA · On-site

$124.40K - $170.60K/yr

Senior DevSecOps Engineer Location: Boston, MA Employment Type: Full-Time Experience: 10+ Years ... Develop automation scripts and workflows using Python, Bash, Go, or PowerShell . * Integrate SIEM ...

Senior Software Engineer

Waltham, MA · On-site

$132.20K - $174.20K/yr

Xometry is seeking a Senior Software Engineer to join our software engineering organization. In ... Reading, writing, and reviewing code written in HTML, Typescript/Javascript/React, Python, and Rust

Senior Associate, Data Engineer

Boston, MA · On-site

$115.30K - $156.60K/yr

Position Description Partners Capital is seeking a talented data engineer to join our Boston data ... Preferred: • Understanding common design patterns & data modelling for python application ...

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Senior Python Engineer information

See Massachusetts salary details

$60.1K

$155.1K

$213K

How much do senior python engineer jobs pay per year?

As of May 30, 2026, the average yearly pay for senior python engineer in Massachusetts is $155,055.00, according to ZipRecruiter salary data. Most workers in this role earn between $132,700.00 and $178,600.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.
What are the most commonly searched types of Python Engineer jobs in Massachusetts? The most popular types of Python Engineer jobs in Massachusetts are:
What are popular job titles related to Senior Python Engineer jobs in Massachusetts? For Senior Python Engineer jobs in Massachusetts, the most frequently searched job titles are:
What job categories do people searching Senior Python Engineer jobs in Massachusetts look for? The top searched job categories for Senior Python Engineer jobs in Massachusetts are:
What cities in Massachusetts are hiring for Senior Python Engineer jobs? Cities in Massachusetts with the most Senior Python Engineer job openings:
Infographic showing various Senior Python Engineer job openings in Massachusetts as of May 2026, with employment types broken down into 77% Full Time, 18% Part Time, 1% Temporary, and 4% Contract. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $155,055 per year, or $74.5 per hour.

Senior Back-End Engineer

Venus Consultancy

Boston, MA • On-site

Full-time

Posted 6 days ago


Job description

Role: Senior Back-End Engineer
Location: Cambridge, MA | In-Person
 
About us
We are a Seed Stage Generative AI startup based in Cambridge, MA. Our mission is to automate custom software creation and unlock the next industrial revolution. Backed by top-tier investors, our founders have a track record of success, holding dozens of Generative AI patents and leading previous startups to success.
 
About the Role
We are seeking a Senior Back-End Engineer to take ownership of various parts of our tech stack. Working directly with our CTO and founding team, you’ll play a crucial role in product development, technical decision-making, and shaping the company’s culture.
We are solving challenging engineering problems at the intersection of AI, cloud infrastructure, and enterprise software development. This role is ideal for someone who is curious, driven, and eager to build from the ground up.
 
What Success Looks Like
You write, review, and deploy high-quality, production-ready code.
You use Generative AI tools to enhance software development and increase efficiency.
You make technical architecture decisions that balance speed, quality, and safety.
You take ownership of your work, ensuring reliability and scalability.
You thrive in an in-person, fast-paced startup environment and collaborate effectively with cross-functional teams.
You can learn quickly, even when working with technologies outside your comfort zone.
You contribute to our engineering culture, setting the foundation for best practices and long-term success.
 
Areas of Ownership
As a Senior Back-End Engineer, you’ll be expected to demonstrate generalist capabilities with deep expertise in Back-End Technologies.
Required Skills & Experience
Expertise in Python, Terraform, and GCP (Google Cloud Platform)
Experience with at least some of the following:
Backend Frameworks & Technologies: Node.js, NuxtJS, Express.js, Python
Cloud Platforms: Google Cloud, AWS, Azure, VercelProgramming 
Languages: Python, JavaScript, TypeScript, Java, C++, Go
APIs & RPCs: REST, gRPC, GraphQL
Databases: SQL, NoSQL, PostgreSQL, MongoDB, Firebase
CI/CD Tools: Jenkins, CircleCI, GitLab
Version Control: Git, Perforce
Microservices Architecture
 
Ways to Stand Out
Experience with AI Platforms: OpenAI, Anthropic, Hugging Face, Vertex AI, Bedrock, SageMaker
Enterprise-Scale Development: Building applications with >99% SLAs
Extensive Experience in Python, Terraform, and GCP
 
Our Culture
We operate with a low-ego, high-output mindset. Our team moves fast, prioritizing action over perfection. We believe in work-life balance, making time for personal well-being while maintaining a high-performance environment.
We prioritize speed on all two-way door decisions.
We encourage curiosity, autonomy, and problem-solving.
We value collaboration but also expect team members to own their work.
We believe in being everyday athletes—optimizing mental and physical health for peak performance.
We leave the office in time for dinner with our families most nights.
 
Are You Up for the Challenge?
Startups are demanding, ever-changing, and require high levels of autonomy. If that excites you rather than intimidates you, we’d love to hear from you!