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Senior Python Engineer Jobs in California (NOW HIRING)

Senior GenAI Engineer (Python)

Palo Alto, CA · On-site

$142K - $192K/yr

We are looking for an experienced Python developer with a passion for Generative AI and hands-on expertise in cloud development. As a Senior GenAI Developer, you will lead the design, development ...

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We are looking for an experienced Python developer with a passion for Generative AI and hands-on expertise in cloud development. As a Senior GenAI Developer, you will lead the design, development ...

Senior GenAI Engineer (Python)

Palo Alto, CA · Hybrid

$142K - $192K/yr

We are looking for an experienced Python developer with a passion for Generative AI and hands-on expertise in cloud development. As a Senior GenAI Developer, you will lead the design, development ...

Sr Staff Python Engineer

Alameda, CA · On-site

$160 - $200/hr

As a Sr. Staff Software Engineer on the software team, you will be writing software to automate ... You have strong coding skills, our stack is primarily Python and TypeScript, but we interact with C ...

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The Senior Software Engineer (Python / AWS) is a key member of the Data Modernization & Integration organization , responsible for building and supporting scalable cloud-native solutions that enable ...

Partner with product managers, senior developers, and industry experts to understand project goals ... Proficiency in Python and libraries such as PyTorch, Pandas, NumPy, or similar. * Familiarity with ...

Partner with product managers, senior developers, and industry experts to understand project goals ... Proficiency in Python and libraries such as PyTorch, Pandas, NumPy, or similar. * Familiarity with ...

Python Senior Software Engineer

San Jose, CA · On-site

$117K - $234K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Owns scoped feature or model delivery through collaborative engineering teams. Manages ... Writes clean, efficient, and reliable code using languages such as JavaScript, TypeScript, Python ...

Showing results 41-60

Senior Python Engineer information

See California salary details

$54.3K

$140.1K

$192.4K

How much do senior python engineer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior python engineer in California is $140,116.00, according to ZipRecruiter salary data. Most workers in this role earn between $119,900.00 and $161,400.00 per year, depending on experience, location, and employer.

What does a senior Python engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the key skills and qualifications needed to thrive as a senior Python engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What are the common challenges senior Python engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.

What are the most commonly searched types of Python Engineer jobs in California?

The most popular types of Python Engineer jobs in California are:

What job categories do people searching Senior Python Engineer jobs in California look for?

The top searched job categories for Senior Python Engineer jobs in California are:

What cities in California are hiring for Senior Python Engineer jobs?

Cities in California with the most Senior Python Engineer job openings:

Infographic showing various Senior Python Engineer job openings in California as of August 2026, with employment types broken down into 95% Full Time, 2% Part Time, and 3% Contract. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution, with an average salary of $140,116 per year, or $67.4 per hour.

Sr. Python Developer AI/ML

Ethereum Technologies LLC

San Francisco, CA • On-site

$140 - $190/hr

Other

Posted yesterday

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Job description

We are seeking a highly motivated and skilled Python Developer with a strong background in Azure cloud services and hands‑on experience in developing and deploying AI/ML solutions, particularly leveraging Retrieval-Augmented Generation (RAG) and vector-based search architectures. This is an exciting opportunity to join our dynamic team and contribute to building innovative and impactful applications. As an Onsite developer, you will collaborate closely with cross-functional teams throughout the development lifecycle.

Responsibilities
  • Design, develop, and deploy scalable and robust AI/ML applications using Python.
  • Implement and optimize Retrieval-Augmented Generation (RAG) pipelines for enhanced information retrieval and generation.
  • Design and implement efficient vector-based search solutions for semantic similarity and information retrieval.
  • Develop and maintain data pipelines for ingestion, processing, and storage of data used in AI/ML models.
  • Collaborate with data scientists and other engineers to understand requirements and translate them into technical solutions.
  • Write clean, well‑documented, and testable code following best practices.
  • Troubleshoot and debug issues in development and production environments.
  • Stay up-to-date with the latest advancements in AI/ML, cloud technologies, and relevant open‑source libraries.
  • Participate in code reviews and contribute to improving our development processes.
  • Work closely with the team in an onsite capacity, fostering collaboration and knowledge sharing.
Qualifications
  • Bachelor's or Master's degree in Computer Science, Engineering, or a related field.
  • Proven experience (typically 5+ years) as a Python Developer.
  • Solid understanding of Python programming concepts and best practices.
  • Strong working knowledge of Azure cloud servicesand their application in AI/ML workloads.
  • Hands‑on experience with AI/ML concepts and libraries(e.g., TensorFlow, PyTorch, scikit‑learn, Hugging Face Transformers).
  • Significant experience in implementing Retrieval-Augmented Generation (RAG) architectures.
  • Experience in designing and implementing vector-based search solutionsusing technologies like ChromaDB, FAISS, Annoy, or similar.
  • Experience with data processing and storage technologies (e.g., SQL, NoSQL databases, Azure Data Lake Storage).
  • Familiarity with containerization technologies like Docker and orchestration platforms like Kubernetes (preferably Azure Kubernetes Service - AKS).
  • Experience with CI/CD pipelines and DevOps practices.
  • Strong problem‑solving and analytical skills.
  • Excellent communication and collaboration skills.
  • Ability to work independently and as part of a team in an onsite environment.
Preferred Qualifications
  • Experience with specific Azure AI services like Azure OpenAI Service.
  • Experience with MLOps practices and tools for deploying and monitoring AI/ML models.
  • Familiarity with natural language processing (NLP) techniques.

ETHEREUM TECHNOLOGIES LLC is an equal opportunity employer inclusive of female, minority, disability and veterans, (M/F/D/V). Hiring, promotion, transfer, compensation, benefits, discipline, termination and all other employment decisions are made without regard to race, color, religion, sex, sexual orientation, gender identity, age, disability, national origin, citizenship/immigration status, veteran status or any other protected status. ETHEREUM TECHNOLOGIES LLC will not make any posting or employment decision that does not comply with applicable laws relating to labor and employment, equal opportunity, employment eligibility requirements or related matters. Nor will ETHEREUM TECHNOLOGIES LLC require in a posting or otherwise U.S. citizenship or lawful permanent residency in the U.S. as a condition of employment except as necessary to comply with law, regulation, executive order, or federal, state, or local government contract.

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