1

Senior Python Developer Jobs in Palmdale, CA (NOW HIRING)

Senior DevOps Engineer

Los Angeles, CA ยท On-site

$140K - $179K/yr

Machina Labs is seeking a Senior DevOps Engineer to join our growing software engineering team and ... Familiarity with Python and/or JavaScript to support automation, tooling, or platform integration.

Senior DevOps Engineer

Chatsworth, CA ยท On-site

$155K - $185K/yr

Machina Labs is seeking a Senior DevOps Engineer to join our growing software engineering team and ... Familiarity with Python and/or JavaScript to support automation, tooling, or platform integration.

Sr Software Engineer

Glendale, CA ยท Hybrid

$129K - $171K/yr

Title-- Sr Software Engineer position Location-- (hybrid; 0 - 3 days onsite will vary according to ... Python โ€ข Relational databases (MySQL, Postgres), and NoSQL databases (DynamoDB) โ€ข Event or pub ...

Senior Security Engineer

Los Angeles, CA ยท Hybrid

$123K - $169K/yr

The role of a Senior Security Engineer in 2026 has evolved from a traditional "firewall gatekeeper ... Engineering Proficiency in Python, Go, or Rust for building custom security tooling and automation.

Senior Security Engineer

Los Angeles, CA ยท Hybrid

$123K - $169K/yr

The role of a Senior Security Engineer in 2026 has evolved from a traditional "firewall gatekeeper ... Engineering Proficiency in Python, Go, or Rust for building custom security tooling and automation.

Senior Security Engineer

Los Angeles, CA ยท Hybrid

$123K - $169K/yr

The role of a Senior Security Engineer in 2026 has evolved from a traditional "firewall gatekeeper ... Engineering Proficiency in Python, Go, or Rust for building custom security tooling and automation.

Senior Security Engineer

Los Angeles, CA ยท On-site +1

$123K - $169K/yr

The role of a Senior Security Engineer in 2026 has evolved from a traditional "firewall gatekeeper ... Engineering Proficiency in Python, Go, or Rust for building custom security tooling and automation.

Senior Mechanical Engineer

Los Angeles, CA ยท On-site

$112K - $148K/yr

Senior Mechanical Engineer Parallel Systems is seeking a Senior Mechanical Engineer with expertise ... Proficiency in Python, MATLAB, or similar scripting tools for simulation automation.

Senior Software Engineer

Los Angeles, CA ยท On-site

$160K - $190K/yr

Senior Software Engineer We're looking for a full-time Senior Software Engineer to join us in our ... Use AI-augmented workflows (Claude) to build and deploy full-stack features using Python (Backend ...

Senior Software Engineer

Los Angeles, CA ยท On-site

$160K - $190K/yr

Senior Software Engineer We're looking for a full-time Senior Software Engineer to join us in our ... Use AI-augmented workflows (Claude) to build and deploy full-stack features using Python (Backend ...

Senior Software Engineer

South Pasadena, CA ยท On-site

$132K - $174K/yr

Elementary is seeking an experienced python Senior Software Engineer. If you want to deploy and run cutting edge AI algorithms on real production lines with strict timing requirements, this is the ...

Senior Software Engineer

South Pasadena, CA ยท Hybrid

$132K - $174K/yr

Elementary is seeking an experienced python Senior Software Engineer. If you want to deploy and run cutting edge AI algorithms on real production lines with strict timing requirements, this is the ...

Senior AI Engineer

Los Angeles, CA ยท Hybrid

$112K - $154K/yr

Job Summary Seeking a Senior AI Engineer with strong expertise in Generative AI, AWS cloud services ... Python Development, APIs, and Microservices * CI/CD, Docker, Kubernetes, and MLOps * AI ...

next page

Showing results 1-20

Senior Python Developer information

See Palmdale, CA salary details

$58.8K

$151.8K

$208.4K

How much do senior python developer jobs pay per year?

As of Jun 21, 2026, the average yearly pay for senior python developer in Palmdale, CA is $151,756.00, according to ZipRecruiter salary data. Most workers in this role earn between $129,900.00 and $174,800.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a Senior Python Developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

What are the key skills and qualifications needed to thrive as a Senior Python Developer, and why are they important?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by Senior Python Developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What cities near Palmdale, CA are hiring for Senior Python Developer jobs? Cities near Palmdale, CA with the most Senior Python Developer job openings:
Senior DevOps Engineer

Senior DevOps Engineer

Machina Labs

Los Angeles, CA โ€ข On-site

$140K - $179K/yr

Full-time

Posted 11 days ago


Job description

About Machina Labs:

Engineering moves at software speed. Manufacturing doesn't. Yet.ย 

Machina Labs is changing that. We build intelligent, software-defined factories that produce complex metal structures directly from digital design. By integrating advanced metal forming, robotics, and automated production inside a flexible factory architecture, we enable customers to move from prototype to production in weeks, not years.ย 

Backed by Lockheed Martin, Toyota, and NVIDIA,ย we'reย building the manufacturing infrastructureย that defense, aerospace, and advanced mobility programs will run on.ย 

If you want to work on hard problems that matter and see them fly, drive, and defend, this is the place.ย 

Job Description:
Machina Labs is seeking a Senior DevOps Engineer to join our growing software engineering team and help build the infrastructure that powers our advanced robotics manufacturing platform.
In this role, you will design, scale, and own the cloud infrastructure, CI/CD pipelines, and deployment systems that support our robotics software platform. You will play a key role in defining how we deploy, secure, monitor, and manage systems across multiple environments, enabling reliable and scalable operations for our robotics and manufacturing systems.
This is an opportunity for an experienced engineer to lead infrastructure strategy, streamline development workflows, and partner closely with software engineers to deliver highly reliable systems. You will be hands-on from day one and help shape the DevOps function as the company grows.

Key Responsibilities:
  • Design, deploy, and manage Azure-based cloud infrastructure, including Azure Government environments.
  • Build and maintain CI/CD pipelines to support automated build, testing, and deployment workflows.
  • Develop and manage Infrastructure as Code using Terraform.
  • Manage and maintain Linux-based systems and services across development and production environments.
  • Support containerized deployments using technologies such as Docker and Kubernetes.
  • Manage secrets, certificates, and authentication across services and environments.
  • Implement system observability including logging, monitoring, alerting, and tracing.
  • Troubleshoot infrastructure and deployment issues and help define operational best practices.
  • Collaborate with engineering teams to improve deployment speed, reliability, and system performance.
Required Background & Experience:
  • 5+ years of experience in DevOps, Site Reliability Engineering, or cloud infrastructure roles.
  • Strong experience with Microsoft Azure cloud infrastructure.
  • Deep experience working with Linux-based environments.
  • Proven experience building and maintaining CI/CD pipelines (GitHub Actions, Azure DevOps, or similar).
  • Hands-on experience with Terraform for infrastructure automation.
  • Experience deploying and managing containerized applications (Docker and/or Kubernetes).
  • Familiarity with Python and/or JavaScript to support automation, tooling, or platform integration.
  • Experience with monitoring and observability tools such as Prometheus, Grafana, or Datadog.
  • Strong troubleshooting skills and ability to manage complex cloud infrastructure.
Preferred Qualifications:
  • Experience supporting infrastructure for robotics, hardware, or real-time systems.
  • Familiarity with Azure Government or regulated cloud environments.
  • Experience with HashiCorp tooling such as Vault or Consul.
  • Experience optimizing cloud infrastructure performance and cost.
ย 
*This job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities required for this role. Duties and responsibilities may change based on business needs.
Machina Labs is an Affirmative Action and Equal Employment Opportunity employer and considers all applicants for employment without regard to race, color, religion, sex, gender identity, gender expression, sexual orientation, national origin, age, disability, or status as a protected veteran in accordance with state and federal law.ย 
ย 
We endeavor to make the job application process accessible to any and all users. If you have a disability that impacts your ability to complete the job application process and would like to request assistance or a reasonable accommodation, please contact us at (888)444-9777. This contact information is for accommodation requests only, not to inquire about the status of applications.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.