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Senior Python Developer Jobs in Opelika, AL (NOW HIRING)

Senior Machine Learning Engineer What you will do Let's do this. Let's change the world. In this ... Experience in DevOps tools (e.g., Docker, Kubernetes, CI/CD) * Proficiency in Python and relevant ...

As a senior Data Engineer at Booz Allen, you will design and build data platforms and pipelines ... Develop secure, efficient Python for data processing, automation, and warehousing. * Migrate and ...

Senior Python Developer information

See Opelika, AL salary details

$50.5K

$130.3K

$179K

How much do senior python developer jobs pay per year?

As of Aug 12, 2026, the average yearly pay for senior python developer in Opelika, AL is $130,349.00, according to ZipRecruiter salary data. Most workers in this role earn between $111,500.00 and $150,100.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

How much does a senior Python developer make?

A senior Python developer's salary typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may have certifications or experience with cloud platforms, which can influence compensation.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What are the most commonly searched types of Python Developer jobs in Opelika, AL? The most popular types of Python Developer jobs in Opelika, AL are:
What cities near Opelika, AL are hiring for Senior Python Developer jobs? Cities near Opelika, AL with the most Senior Python Developer job openings:
Infographic showing various Senior Python Developer job openings in Opelika, AL as of August 2026, with employment types broken down into 2% Internship, 80% Full Time, 12% Part Time, and 6% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $130,349 per year, or $62.7 per hour.

Sr Machine Learning Engineer

Amgen SA

Auburn, AL • On-site

$140 - $190/hr

Other

Medical, Dental, Vision, Life, Retirement

Posted 7 days ago


Job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Machine Learning Engineer

What you will do

Let’s do this. Let’s change the world. In this vital role you will play a pivotal role in building and scaling our machine learning models from development to production. Your expertise in both machine learning and operations will be essential in creating efficient and reliable ML pipelines.

Roles & Responsibilities:

  • Collaborate with data scientists to develop, train, and evaluate machine learning models.

  • Build and maintain MLOps pipelines, including data ingestion, feature engineering, model training, deployment, and monitoring.

  • Leverage cloud platforms (AWS, GCP, Azure) for ML model development, training, and deployment.

  • Implement DevOps/MLOps best practices to automate ML workflows and improve efficiency.

  • Develop and implement monitoring systems to track model performance and identify issues.

  • Conduct A/B testing and experimentation to optimize model performance.

  • Work closely with data scientists, engineers, and product teams to deliver ML solutions.

  • Stay updated with the latest trends and advancements

Must-Have Skills:

  • Solid foundation in machine learning algorithms and techniques

  • Experience in MLOps practices and tools (e.g., MLflow, Kubeflow, Airflow); Experience in DevOps tools (e.g., Docker, Kubernetes, CI/CD)

  • Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn)

  • Outstanding analytical and problem-solving skills; Ability to learn quickly; Good communication and interpersonal skills

Good-to-Have Skills:

  • Experience with big data technologies (e.g., Spark, Hadoop), and performance tuning in query and data processing

  • Experience with data engineering and pipeline development

  • Experience in statistical techniques and hypothesis testing, experience with regression analysis, clustering and classification

  • Knowledge of NLP techniques for text analysis and sentiment analysis

  • Experience in analyzing time-series data for forecasting and trend analysis

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek will have these qualifications.

Basic Qualifications:

Doctorate degree
OR
Master’s degree and 2 years of Computer Science experience
OR
Bachelor’s degree and 4 years ofComputer Science experience
OR
Associate’s degree and 8 years of Computer Science experience
OR
High school diploma / GED and 10 years of Computer Science experience

Preferred Qualifications:

  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus.

Soft Skills:

  • Excellent analytical and troubleshooting skills.

  • Strong verbal and written communication skills

  • Ability to work effectively with global, virtual teams

  • High degree of initiative and self-motivation.

  • Ability to manage multiple priorities successfully.

  • Team-oriented, with a focus on achieving team goals.

  • Ability to learn quickly, be organized and detail oriented.

  • Strong presentation and public speaking skills.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans

  • Flexible work models, including remote and hybrid work arrangements, where possible

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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