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Senior Python Developer Jobs in Laguna Niguel, CA

Neara

Sr. DevOps Engineer

Irvine, CA · On-site

$139K - $179K/yr

Sr. DevOps Engineer Job type: Full Time · Department: Technology and Development · Work type: On ... such as TypeScript or Python * Experience designing and operating monitoring, logging, and ...

Socket.dev

Sr. DevOps Engineer

Irvine, CA · On-site

$139K - $179K/yr

Senior DevOps Engineer At EKN Engineering, we solve challenging problems with innovative ... such as TypeScript or Python * Experience designing and operating monitoring, logging, and ...

Ingrammicro

Sr DevOps Engineer - Lead

Irvine, CA · On-site +1

$112K - $190K/yr

Seeking a Senior DevOps Engineer to DriveGlobal DevOpsExcellence at Ingram Micro, a global leader ... Proficiencyin scripting languages such as Python, Bash, or PowerShell. * Solid understanding of ...

Message Broadcast

Senior Software Engineer

Newport Beach, CA · On-site

$131K - $173K/yr

We are seeking a Senior Software Engineer to lead the development and scaling of our messaging ... Proficient in multiple programming languages (e.g., Java, Python, C++). * Experience with cloud ...

CoStar Group

Senior DevOps Engineer

Irvine, CA · On-site

$139K - $179K/yr

Senior DevOps Engineer Overview CoStar Group (CSGP) is a leading global provider of commercial and ... Programming languages / some developer background with either Java, C#,Python, NodeJS * Server-less ...

CoStar Group, Inc.

Senior DevOps Engineer

Irvine, CA · On-site

$139K - $179K/yr

Senior DevOps Engineer Overview CoStar Group (CSGP) is a leading global provider of commercial and ... Programming languages / some developer background with either Java, C#, Python, NodeJS Server-less ...

CoStar

Senior DevOps Engineer

Irvine, CA · On-site

$139K - $179K/yr

Senior DevOps Engineer Overview CoStar Group (CSGP) is a leading global provider of commercial and ... Programming languages / some developer background with either Java, C#, Python, NodeJS Server-less ...

Solugenix Corporation

Senior Kafka Engineer

Irvine, CA · On-site

$80 - $85/hr

... DevOps, and architecture teams. Required Skills & Experience: * 10+ years of experience in ... Experience integrating Kafka with Java and Python applications. * Experience with Kafka Connect and ...

Visual Lease

Senior DevOps Engineer

Irvine, CA · On-site

$139K - $179K/yr

Senior DevOps Engineer CoStar Group (CSGP) is a leading global provider of commercial and ... Programming languages / some developer background with either Java, C#, Python, NodeJS * Server ...

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Showing results 21-40

All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Laguna Niguel, CA

Senior Python Developer information

See Laguna Niguel, CA salary details

$55.6K

$143.5K

$197.1K

How much do senior python developer jobs pay per year?

As of Sep 12, 2026, the average yearly pay for senior python developer in Laguna Niguel, CA is $143,512.00, according to ZipRecruiter salary data. Most workers in this role earn between $122,800.00 and $165,300.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are popular job titles related to Senior Python Developer jobs in Laguna Niguel, CA?

For Senior Python Developer jobs in Laguna Niguel, CA, the most frequently searched job titles are:

What cities near Laguna Niguel, CA are hiring for Senior Python Developer jobs?

Cities near Laguna Niguel, CA with the most Senior Python Developer job openings:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Laguna Niguel, CA as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 9% Part Time, and 6% Contract. Highlights an 80% Physical, 6% Hybrid, and 14% Remote job distribution, with an average salary of $143,512 per year, or $69 per hour.

Senior Manufacturing Test Engineer

Irvine, CA • On-site

Beta Bionics
See more jobs at Beta Bionicsexternal

$110K - $135K/yr

Full-time

Medical, Dental, Retirement, PTO

Re-posted 6 days ago

Job description

About Beta Bionics
Beta Bionics, Inc. is a medical technology company dedicated to bringing innovative type 1 diabetes management solutions to the many, not the few. We are committed to bringing better access to better solutions - and a better life for those living with diabetes - with the world's first bionic pancreas called the iLet. The iLet Bionic Pancreas is the first and only insulin delivery system that does not require carb counting*, bolusing, correction factors, or pre-set basal rates. The only number needed to get started with the iLet Bionic Pancreas is a user's weight - the iLet does the rest. The iLet lets users "Go Bionic" with their diabetes management.
*User must be carb aware.
Successful candidates will be working with highly experienced colleagues, who are amongst the best in their fields. We have a mission-driven, passionate and collaborative culture where you will have a high degree of empowerment and opportunity to make a significant impact.
Please contact us if you fit the profile below and if you are interested in joining the Beta Bionics team!
Summary/Objective:
The Senior Manufacturing Test Engineer leads the development, implementation, and optimization of manufacturing test processes and advanced automated test systems. This role ensures product quality and reliability by designing robust test methods, developing scalable software-driven solutions, and owning the full equipment validation lifecycle, including in-house Factory Acceptance Testing (FAT), Site Acceptance Testing (SAT), and IQ/OQ/PQ. The role also drives technical leadership, standardization, and continuous improvement across manufacturing operations.
Primary Duties and Responsibilities
[Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Qualified candidates who need a reasonable accommodation with the application process and/or to perform the essential functions of the position should notify the company's HR contact]
  • Lead design, development, and validation of manufacturing test methods, fixtures, and complex automated test systems
  • Architect, develop, and maintain scalable test software using Python for data acquisition, execution, and analysis
  • Integrate test hardware with software platforms (DAQ systems, sensors, PLCs) and ensure system-level performance
  • Drive test automation, data integrity, and system standardization across manufacturing lines
  • Define and lead test strategy for new product introduction (NPI) and scale to production
  • Own and lead in-house Factory Acceptance Testing (FAT) to verify equipment functionality and performance
  • Lead Site Acceptance Testing (SAT), installation, and commissioning activities
  • Define and drive full validation lifecycle (IQ/OQ/PQ) including protocol development and execution
  • Troubleshoot complex system-level issues across hardware, software, and processes
  • Analyze large datasets using Python, SQL, or similar tools to drive yield improvement and cost reduction
  • Collaborate and lead cross-functional technical discussions with R&D, Quality, Manufacturing, and leadership
  • Develop and maintain test documentation, software scripts, FAT/SAT protocols, and validation reports
  • Ensure compliance with regulatory standards (FDA, ISO 13485, GMP)
  • Mentor junior engineers and technicians
  • Lead continuous improvement initiatives and test automation roadmap development

Required Qualifications
  • Bachelor's (Master's preferred) in Electrical, Mechanical, Biomedical, Computer Engineering, or related field
  • 5-8+ years of experience in manufacturing test engineering
  • Advanced experience with Python programming (test automation, data analysis, equipment control)
  • Strong experience leading in-house FAT/SAT and validation (IQ/OQ/PQ)
  • Deep knowledge of test equipment and systems (DAQ, sensors, PLCs, automation)
  • Strong problem-solving and root cause analysis skills (5 Whys, Fishbone, DOE)

Preferred Qualifications
  • Experience designing custom automated equipment and test platforms
  • Strong data analytics and visualization skills (Python, SQL, Pandas)
  • Experience with MES systems and digital manufacturing integration
  • Medical device or highly regulated industry experience
  • Lean / Six Sigma certification (Black Belt preferred)

Key Competencies
  • Technical leadership and system-level thinking
  • Strong software + hardware integration expertise
  • Ownership of full validation lifecycle (FAT → SAT → IQ/OQ/PQ)
  • Hands-on troubleshooting across hardware and software systems
  • Strategic mindset with strong execution capability
  • Excellent cross-functional communication and leadership skills

Work Environment and Personal Protective Equipment
  • This job operates in a professional office environment. This role routinely uses standard office equipment such as computers, phones, photocopiers, and scanners.
  • Personal Protective Equipment may be required for laboratory or field work.

Physical Demands
  • While performing the duties of this job, the employee is regularly required to stand; walk; sit; use hands to handle or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, see, talk, or hear.
  • Specific vision abilities required by this job include close vision, color vision, and ability to adjust focus.
  • Employee must occasionally lift and/or move up to 50 pounds.
  • Wears personal protective equipment as required.
  • This position requires up to five (5%) percent travel.

Location
  • This position is based out of our office in Irvine, California.

Salary Range
$110,000 - $135,000
Benefits
  • Comprehensive medical and dental coverage
  • FSA and HSA Plan Options, including an annual company contribution to the HSA
  • 401(k) program with employer match
  • Generous vacation accrual and paid holiday schedule

Equal Employment Opportunity Statement
It is the policy of Beta Bionics to provide equal employment opportunity to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Beta Bionics will provide reasonable accommodations for qualified individuals with disabilities.

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