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Senior Python Automation Jobs in San Diego, CA (NOW HIRING)

Senior Automation Engineer

San Diego, CA ยท On-site

$55 - $64/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The Senior Automation Engineer is responsible for driving the design, deployment, and optimization ... Python,Software Development Life Cycle,systems engineering,ability to communicate effectively ...

Python API Engineer

San Diego, CA ยท On-site

  • Medical

  • Retirement

  • PTO

The Senior Software Engineer (Python / AWS) is a key member of the Data Modernization & Integration ... This role combines Python development, AWS cloud engineering, API integration, automation ...

Senior QA Automation Engineer

San Diego, CA ยท On-site

$145K - $183K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for a skilled Senior QA Automation Engineer to join a newly formed QA team ... Proficiency in Python and/or Node.js for test automation. * Understanding of networking concepts ...

Senior QA Automation Engineer

San Diego, CA ยท On-site

$145K - $183K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for a skilled Senior QA Automation Engineer to join a newly formed QA team ... Proficiency in Python and/or Node.js for test automation. * Understanding of networking concepts ...

Senior Software Engineer

Temecula, CA ยท On-site

$150K - $175K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

Senior Software Engineer / Technical Leader (Individual Contributor) Core Technologies: C/C ... Develop Python-based automation, testing frameworks, developer tools, and maintenance utilities.

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Showing results 1-20

Senior Python Automation information

See San Diego, CA salary details

$58.4K

$150.7K

$207K

How much do senior python automation jobs pay per year?

As of Aug 18, 2026, the average yearly pay for senior python automation in San Diego, CA is $150,737.00, according to ZipRecruiter salary data. Most workers in this role earn between $129,000.00 and $173,600.00 per year, depending on experience, location, and employer.

Is senior Python automation a good career?

Senior Python automation roles are in high demand across industries such as finance, technology, and manufacturing, as organizations seek to improve efficiency through scripting and process automation. These positions typically require strong programming skills, knowledge of automation tools like Selenium or Jenkins, and experience with software development best practices. The career offers opportunities for advancement, specialization, and competitive salaries, making it a solid choice for those with expertise in Python and automation.

Which Senior Python Automation job has the highest salary?

Senior Python Automation roles typically offer high salaries, especially in industries like finance, technology, and data science. The highest salaries are often found in large tech companies or financial institutions, where advanced automation skills, experience, and knowledge of tools like Selenium, Jenkins, or cloud platforms are valued. Salaries can exceed $130,000 annually, depending on location, company size, and candidate expertise.

What are the most commonly searched types of Python Automation jobs in San Diego, CA?

The most popular types of Python Automation jobs in San Diego, CA are:

What are popular job titles related to Senior Python Automation jobs in San Diego, CA?

For Senior Python Automation jobs in San Diego, CA, the most frequently searched job titles are:

What cities near San Diego, CA are hiring for Senior Python Automation jobs?

Cities near San Diego, CA with the most Senior Python Automation job openings:

Infographic showing various Senior Python Automation job openings in San Diego, CA as of August 2026, with employment types broken down into 1% Internship, 90% Full Time, 5% Part Time, and 4% Contract. Highlights an 84% Physical, 6% Hybrid, and 10% Remote job distribution, with an average salary of $150,737 per year, or $72.5 per hour.

Senior Automation Engineer

Randstad Digital

San Diego, CA โ€ข On-site

$55 - $64/hr

Other

Medical, Dental, Vision, Life, Retirement

Posted 7 days ago


Job description

job summary:

The Senior Automation Engineer is responsible for driving the design, deployment, and optimization of laboratory and production automation architectures. This critical role supports new project initiatives and centers heavily on expanding automated liquid handling capabilities and engineering robust software integrations across enterprise tracking platforms.


location: San Diego, California
job type: Contract
salary: $55 - 64 per hour
work hours: 8am to 5pm
education: Bachelors
responsibilities:

Lead the configuration, programming, and maintenance of automated liquid handling platforms to support business-critical laboratory or production workflows.


Develop, validate, and optimize robust automation protocols to ensure operational efficiency, consistency, and repeatability.


Provide expert-level troubleshooting and technical support for automation hardware and software interfaces, minimizing platform downtime.


Architect, implement, and maintain complex software connections and data pipelines integrating automated laboratory hardware with enterprise systems, specifically LIMS and MES platforms.


Partner closely with IT, Data Engineering, and operations stakeholders to verify seamless data flow, data integrity, and process compliance across connected networks.


Author and manage detailed technical specifications, verification protocols, and operational documentation for integrated automated systems.


qualifications:

- Bachelor of Science (B.S.) degree in Engineering, Biotechnology, Computer Science, or a closely related technical field.


- Minimum of 5 to 10 years of progressive, hands-on experience specializing in laboratory or industrial automation engineering.


- Demonstrated mastery of automated liquid handling technology platforms and their underlying control software.


- Robust, proven experience integrating third-party equipment and automated instruments into LIMS and/or MES environments.


- Strong analytical approach to software debugging, hardware-to-software validation, and systematic data verification.


skills:

C#,programming,data analysis,Computer Science,LIMS,Lynx,object-oriented programming languages,Python,Software Development Life Cycle,systems engineering,ability to communicate effectively,Strong oral and written communication skills,strong analytical and problem-solving skills,problem-solving skills,Strong troubleshooting skills,Automation,automation systems,automated systems,integrated automation systems,Lifesciences,continuous improvement,professional relationships,business needs,Chemical Engineering,Chemistry,concept testing,customer experience,industry developments,instrumentation,comprehensive documentation,Electrical Engineering,Liquid Handling,sealers,Mechanical Engineering,Mechatronics Engineering,automated workflows,process development,method development,project scope,Robotics Engineering,simulation,error handling,system deployment,technical support,automation strategy,testing,validation procedures,workflows



Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.
At Randstad Digital, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact
Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad Digital offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).
This posting is open for thirty (30) days.
Qualified applicants in San Francisco with criminal histories will be considered for employment in accordance with the San Francisco Fair Chance Ordinance.
Qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance.