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Senior Machine Learning Jobs in Massachusetts (NOW HIRING)

C the Signs

Senior Machine Learning Engineer

Boston, MA · On-site +1

$133K - $175K/yr

Position Summary The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data ...

Axon

Senior Machine Learning Scientist

Boston, MA · On-site

$99K - $135K/yr

Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI ... PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML ...

Sierra Ventures

Machine Learning Engineer

Somerville, MA · On-site

$170 - $200/hr

We're looking for a Senior Machine Learning Engineer to help advance the state of voice understanding at Modulate. In this role, you'll design, train, evaluate, and deploy cutting‑edge machine ...

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Senior Machine Learning information

See Massachusetts salary details

$27.3K

$87.7K

$178.6K

How much do senior machine learning jobs pay per year?

As of Sep 2, 2026, the average yearly pay for senior machine learning in Massachusetts is $87,683.00, according to ZipRecruiter salary data. Most workers in this role earn between $45,300.00 and $112,500.00 per year, depending on experience, location, and employer.

What is a senior machine learning engineer?

Senior Machine Learning engineers are experienced professionals who design, develop, and deploy advanced machine learning models and systems. They typically lead projects, mentor junior team members, and collaborate with data scientists, software engineers, and stakeholders to solve complex problems using AI and data-driven techniques. Their responsibilities include researching new algorithms, optimizing model performance, and ensuring the scalability and reliability of machine learning solutions in production environments.

What are the key skills and qualifications needed to thrive as a senior machine learning engineer?

To thrive as a Senior Machine Learning Engineer, you need a strong background in mathematics, statistics, computer science, and experience with designing and deploying machine learning models, typically supported by an advanced degree in a related field. Proficiency with programming languages such as Python or R, ML frameworks like TensorFlow or PyTorch, and experience with cloud platforms and version control systems are commonly required. Excellent problem-solving skills, communication abilities, and leadership in collaborating with cross-functional teams make candidates stand out. These skills ensure the effective development, scaling, and integration of ML solutions to drive business value and innovation.

What are some common challenges senior machine learning engineers face when deploying models to production, and how can they address them?

Senior Machine Learning Engineers often encounter challenges such as ensuring model scalability, maintaining model performance over time, and integrating models seamlessly with existing systems. Addressing these requires robust monitoring frameworks, collaboration with data engineering and DevOps teams, and implementing strategies like continuous integration/continuous deployment (CI/CD) for ML. Proactive communication with stakeholders and staying updated on the latest MLOps tools can also help ensure smooth deployment and ongoing reliability.

Is senior machine learning a high paying job?

Senior machine learning roles typically offer high salaries due to the specialized skills required, such as expertise in algorithms, programming, and data analysis. Compensation varies by industry, location, and experience, but these positions are generally among the higher-paying roles in tech and data science fields.

What are the most commonly searched types of Machine Learning jobs in Massachusetts?

The most popular types of Machine Learning jobs in Massachusetts are:

What are popular job titles related to Senior Machine Learning jobs in Massachusetts?

For Senior Machine Learning jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Senior Machine Learning jobs in Massachusetts look for?

The top searched job categories for Senior Machine Learning jobs in Massachusetts are:

What cities in Massachusetts are hiring for Senior Machine Learning jobs?

Cities in Massachusetts with the most Senior Machine Learning job openings:

Senior Machine Learning jobs near you
Infographic showing various Senior Machine Learning job openings in Massachusetts as of August 2026, with employment types broken down into 1% As Needed, 71% Full Time, 24% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 83% Physical, 3% Hybrid, and 14% Remote job distribution, with an average salary of $87,683 per year, or $42.2 per hour.

Senior Machine Learning Engineer

C the Signs

Boston, MA • On-site, Remote

$133K - $175K/yr

Full-time

Re-posted 8 days ago

Job description

Position Summary
The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data preprocessing, model training, and fine-tuning using large-scale healthcare datasets. This role requires a strong understanding of Large language models, machine learning principles, data engineering, and experience working with sensitive healthcare data.
Key Responsibilities
  • Data Preprocessing: Clean, transform, and prepare large, complex healthcare datasets for machine learning model development. This includes handling missing values, outlier detection, feature engineering, and data normalization. Identify, collect, and curate relevant, industry-specific datasets for model retraining. Format data appropriately for the chosen LLM and training pipeline
  • Model Training & Fine-Tuning: Design, train, and fine-tune various LLMs on extensive healthcare data to solve specific clinical or operational problems. Set up and manage the training environment, including GPU instances and required software. Train and fine-tune pre-trained LLMs on the custom dataset to achieve specific goals. Experiment with and fine-tune hyperparameters such as learning rate, batch size, and training epochs to optimize model performance. Integration of structured + unstructured data (multi-modal/multi-input models)
  • Model Evaluation & Optimization: Evaluate model performance using appropriate metrics, identify areas for improvement, and implement optimization strategies.
  • Pipeline Development: Develop and maintain robust and scalable data and ML pipelines for model training, inference, and deployment.
  • Collaboration: Work closely with data scientists, clinicians, and software engineers to understand requirements, integrate models into production systems, and ensure data privacy and security compliance.
  • Research & Development: Stay up-to-date with the latest advancements in machine learning and healthcare AI, and explore new technologies and methodologies to enhance our solutions.
  • Documentation: Maintain clear and comprehensive documentation of models, data pipelines, and experimental results.

Requirements
  • Education: Bachelor's or Master's degree in Computer Science, Machine Learning, Artificial Intelligence, or a related quantitative field.
  • Experience:
    • 5+ years of experience in Machine Learning Engineering or a similar role.
    • Proven experience with large-scale data preprocessing, LLM/model training, and fine-tuning.
    • Experience with distributed training (PyTorch Distributed, DeepSpeed, Ray, Hugging Face Accelerate).
    • Experience with GPU/TPU optimization, memory management for large language models.
    • Experience working with healthcare data is highly desirable.
  • Technical Skills:
    • Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn, Pandas, NumPy).
    • Strong understanding of various machine learning algorithms,Large Language Models, and deep learning architectures.
    • Experience with cloud platforms (e.g., GCP, AWS) and distributed computing frameworks (e.g., Spark) is a plus.
    • Familiarity with MLOps practices and tools.
  • Soft Skills:
    • Excellent problem-solving and analytical skills.
    • Strong communication and collaboration abilities.
    • Ability to work independently and as part of a team in a fast-paced environment.
  • Work Authorization:
      • Must be a US Citizen, Green Card holder, or currently in the US have valid H1B visa

Benefits
Why Join Us?
Joining C the Signs is not just about building AI; it's about shaping the future of healthcare. If you are a technical leader with an unshakable belief in the power of AI to save lives and the ability to make it happen at scale, this is your opportunity to create a tangible, global impact.
Benefits:
  • Competitive salary and benefits package.
  • Flexible working arrangements (remote or hybrid options available).
  • The opportunity to work on life-changing AI technology that directly impacts patient outcomes.
  • Join a team that combines cutting-edge innovation with a mission to save lives and improve health equity.
  • Continuous learning opportunities with access to the latest tools and advancements in AI and healthcare.

Apply