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Senior Instrument Engineer Jobs in Colorado (NOW HIRING)

I&C Engineer 4

Englewood, CO · On-site

$105K - $135K/yr

Experience with originating and checking standard I&C deliverables including P&ID's, Instrument ... engineering. At least 7 years of job-related experience. Excellent communications and analytical ...

I&C Engineer 4

Englewood, CO · On-site

$105K - $135K/yr

Experience with originating and checking standard I&C deliverables including P&ID's, Instrument ... engineering. At least 7 years of job-related experience. Excellent communications and analytical ...

We are seeking a Senior Network Security Engineer to join our Zero Trust team and serve as a hands ... Instrument and monitor AI agent performance, accuracy, and safety using human feedback loops and ...

Senior Cloud Operations Engineer Location: Denver, CO About the Team The Data Insights Capability ... Establish and instrument our core pipeline Service Level Objectives in Splunk, proactively ...

CAD Sr Designer

Westminster, CO · On-site

$27.25 - $37.50/hr

The Designer is responsible for the integrity of the product, including models and engineering ... instrument systems. Occasional travel and mentoring of junior designers is expected. Principal ...

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Showing results 1-20

Senior Instrument Engineer information

See Colorado salary details

$83.1K

$122.9K

$173.5K

How much do senior instrument engineer jobs pay per year?

As of Jul 13, 2026, the average yearly pay for senior instrument engineer in Colorado is $122,858.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,800.00 and $144,100.00 per year, depending on experience, location, and employer.

What are some common challenges faced by Senior Instrument Engineers when working on multidisciplinary projects?

Senior Instrument Engineers often encounter challenges coordinating with other engineering disciplines, such as process, electrical, and mechanical teams, to ensure instrumentation specifications align with overall project requirements. Integrating new instrumentation technologies into existing systems while maintaining compliance with safety and industry standards can also be demanding. Effective communication, strong project management skills, and adaptability are essential to successfully navigate these complexities and ensure project deliverables are met on time and within budget.

What does a Senior Instrument Engineer do?

A Senior Instrument Engineer is responsible for designing, specifying, installing, and maintaining instrumentation and control systems used in industrial processes. They ensure that these systems function efficiently, safely, and reliably to monitor and control variables such as pressure, temperature, and flow. Senior Instrument Engineers often lead projects, troubleshoot complex issues, and provide technical guidance to junior engineers. They also collaborate with other engineering disciplines to optimize process performance and comply with industry standards.

What are the key skills and qualifications needed to thrive as a Senior Instrument Engineer, and why are they important?

To thrive as a Senior Instrument Engineer, you typically need a degree in engineering (often electrical, instrumentation, or control engineering) and extensive experience with instrumentation design, installation, and maintenance. Proficiency with industry-standard tools such as PLCs, DCS, CAD software, and familiarity with relevant codes and certifications like ISA or IEC are essential. Strong problem-solving, project management, and communication skills help coordinate teams and interface with other engineering disciplines. These skills and qualities ensure the safe, efficient, and reliable operation of complex industrial processes.

What is the difference between Senior Instrument Engineer vs Instrument Technician?

AspectSenior Instrument EngineerInstrument Technician
CredentialsBachelor's degree in Engineering, certifications like CSE or ISATechnical diploma or associate degree, specialized training
Work EnvironmentDesign, project management, troubleshooting in industrial plantsInstallation, maintenance, calibration on-site
Industry UsageEngineering firms, oil & gas, manufacturingRefineries, power plants, process industries

While both roles involve instrumentation, the Senior Instrument Engineer focuses on design, planning, and troubleshooting at a higher level, often overseeing projects. The Instrument Technician handles hands-on installation, maintenance, and calibration tasks. Both roles are essential in industrial settings but differ in responsibilities and required qualifications.

What are the most commonly searched types of Instrument Engineer jobs in Colorado? The most popular types of Instrument Engineer jobs in Colorado are:
What cities in Colorado are hiring for Senior Instrument Engineer jobs? Cities in Colorado with the most Senior Instrument Engineer job openings:

Senior Analog & Mixed-Signal Engineer (Precision Timing)

Mesa Quantum Systems

Boulder, CO • On-site

$150K - $230K/yr

Full-time

Re-posted 2 days ago


Job description

About Mesa Quantum

Mesa Quantum is building the manufacturing backbone of the quantum economy. We specialize in chip-scale quantum devices, starting with clocks and sensors, that unlock resilient Position, Navigation, and Timing (PNT) for defense, telecom, space, and critical infrastructure. Our team combines world-class expertise in AMO physics, photonics, microfabrication, and engineering to transform breakthrough science into scalable, deployable technology. Backed by top-tier deep-tech investors and the U.S. Department of Defense, MesaQuantum is rapidly scaling and actively recruiting exceptional innovators who want to build the future of quantum technology from the ground up.

The Role

We are hiring a Senior Analog & Mixed-Signal Engineer to lead the development of the precision control electronics at the core of our chip-scale atomic clock platform. You will own the analog front-end, signal conditioning, and control loop architecture that takes our physics package from benchtop validation to fielded product, partnering with our AMO physics, photonics, RF, and systems teams.

This is a hands-on senior role. You are expected to personally execute the bulk of the analog circuit design work, from schematic capture and simulation through bench bring-up and characterization. We are looking for an engineer who is genuinely passionate about designing circuits, takes pride in elegant analog topology, and would rather be at the bench than in front of slides. The work spans precision analog, mixed-signal PCB design, and RF synthesis, with frequent interfacing to the embedded and digital teams. Reports to the CTO.

This is a full-time, on-site position in Boulder, CO.

Key Responsibilities
  • Own the precision analog front-end: photodetector signal conditioning, low-noise transimpedance and instrumentation amplification, and lock-in detection for weak atomic signal recovery
  • Architect and deliver successive generations of the control electronics, driving size, power, and noise improvements at each iteration
  • Design and validate the microwave synthesis chain that drives atomic interrogation, including PLL and VCO architecture, phase noise optimization, and reference distribution
  • Implement precision VCSEL current drive and thermal control electronics for the laser and physics package
  • Build characterization protocols, test fixtures, and automation to validate clock performance against Allan deviation, phase noise, and holdover targets
  • Drive Design for Manufacturability and Design for Test with PCB houses and contract manufacturers as we scale toward high-volume production
  • Mentor junior engineers and act as the senior technical voice in hardware design reviews

Requirements

Required Skills & Experience
  • 10+ years of analog and mixed-signal hardware design, including at least one product taken from prototype through volume production
  • Deep expertise in low-noise precision analog: signal conditioning, low-noise amplifiers, ADC/DAC interfacing, and rigorous noise budgeting
  • Mixed-signal PCB design: multi-layer stack-ups with sensitive analog, RF, and digital domains on a single board; controlled impedance; thermal management; debug experience under signal integrity constraints
  • RF circuit design through GHz, with hands-on experience in low phase noise frequency synthesis, PLLs, and VCOs
  • Strong SPICE simulation and circuit analysis skills, including noise, stability, and tolerance analysis
  • Hands-on proficiency with oscilloscopes, spectrum and phase noise analyzers, network analyzers, source measure units, and signal generators
  • Scripting experience for instrument control, characterization, and data analysis
  • Experience using Git or similar version-control systems within a hardware development environment
Strongly Preferred
  • Chip-scale atomic clocks, rubidium or cesium oscillators, OCXOs, or other precision frequency references
  • Optoelectronics: VCSEL drive design, photodetector readout, laser frequency locking
  • Embedded firmware in C/C++ on ARM Cortex-M class microcontrollers
  • FPGA development in Verilog or SystemVerilog, including real-time DSP IP (lock-in detection, PID, digital filtering)
  • Mixed-signal ASIC familiarity, particularly mixed-signal block specification, verification, or characterization
  • Hardware design under hard size and power budgets (low SWAP-C)
  • Production partnerships with contract manufacturers and PCB houses, including DFM and DFT contribution
  • Defense, aerospace, or space-qualified hardware experience
  • Familiarity with atomic physics or other quantum sensing modalities
Eligibility

Due to U.S. Department of Defense funding requirements, applicants must be U.S. persons (U.S. citizens or lawful permanent residents). The ability to obtain and maintain a U.S. security clearance may be required for certain projects.

Benefits

What We Offer
  • Competitive base salary in the range of $150K to $230K, commensurate with experience, skills, qualifications, and education. Most candidates who meet the minimum qualifications will be hired within the middle portion of the range; placement above the midpoint requires demonstrated expertise significantly beyond the role's minimum requirements, and offers at the top of the range are atypical
  • Meaningful equity in a deep-tech company at the inflection point between prototype and product
  • Comprehensive benefits package
  • Direct ownership of a critical subsystem with measurable impact on a product that matters to U.S. national security
  • A team that includes deep AMO physics, RF, photonics, and microfabrication expertise
  • Boulder location with access to Colorado's strongest tech and outdoor communities