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Senior Csv Engineer Jobs (NOW HIRING)

Tempus

Senior Quality Engineer

Redwood City, CA · On-site +1

As a Senior Quality Engineer , you will: * Lead verification, validation and maintenance of host ... Lead computer system validation (CSV) activities of Tempus AI applications, software tools, and ...

Tempus

Senior Quality Engineer

New York, NY · On-site +1

As a Senior Quality Engineer , you will: * Lead verification, validation and maintenance of host ... Lead computer system validation (CSV) activities of Tempus AI applications, software tools, and ...

Tempus

Senior Quality Engineer

Chicago, IL · On-site +1

As a Senior Quality Engineer , you will: * Lead verification, validation and maintenance of host ... Lead computer system validation (CSV) activities of Tempus AI applications, software tools, and ...

Tempus

Senior Quality Engineer

Chicago, IL · On-site

As a Senior Quality Engineer , you will: * Lead verification, validation and maintenance of host ... Lead computer system validation (CSV) activities of Tempus AI applications, software tools, and ...

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All JobsSenior Csv Engineer Jobs

Senior Csv Engineer information

See salary details

$59.5K

$126.6K

$183.5K

How much do senior csv engineer jobs pay per year?

As of Jun 9, 2026, the average yearly pay for senior csv engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior CSV Engineer, and why are they important?

To excel as a Senior CSV (Computer System Validation) Engineer, you need expertise in validation methodologies, regulatory compliance (such as FDA 21 CFR Part 11, GAMP 5), and a relevant engineering or scientific degree. Proficiency with validation lifecycle documentation, risk management tools, and quality management systems is typically required, as are certifications like PMP or Six Sigma. Strong analytical skills, attention to detail, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring compliance. These skills are essential to maintaining regulatory standards, minimizing risks, and ensuring the integrity and reliability of computerized systems in regulated industries.

What is the difference between Senior Csv Engineer vs Data Engineer?

AspectSenior Csv EngineerData Engineer
Required CredentialsBachelor's in Computer Science, Data Science, or related field; experience with CSV processingBachelor's or higher in Computer Science, Data Engineering, or related; often includes knowledge of databases and ETL tools
Work EnvironmentData processing teams, analytics departments, data pipelines involving CSV filesData infrastructure teams, big data environments, cloud platforms, and data pipelines
Employer & Industry UsageTech companies, finance, healthcare, any industry handling large CSV datasetsTech firms, finance, e-commerce, and industries requiring large-scale data integration

The main difference is that a Senior Csv Engineer specializes in managing and optimizing CSV data workflows, while a Data Engineer has a broader role in designing and maintaining comprehensive data infrastructure, including databases, pipelines, and big data systems. Both roles require similar foundational skills but differ in scope and complexity.

What are Senior CSV Engineers?

Senior CSV Engineers are experienced professionals who specialize in Computer System Validation (CSV) within regulated industries such as pharmaceuticals, biotechnology, and medical devices. Their main responsibility is to ensure that computer systems used in these industries comply with regulatory standards and function as intended. They lead validation projects, develop validation protocols, conduct risk assessments, and work closely with IT and quality assurance teams. Senior CSV Engineers also provide guidance on regulatory requirements, troubleshoot validation issues, and help maintain audit-ready documentation.

What are common challenges faced by Senior CSV Engineers when ensuring regulatory compliance across multiple projects?

Senior CSV Engineers often encounter the challenge of managing varying compliance standards and documentation requirements across multiple projects, especially when working with global teams. Keeping up-to-date with evolving regulations (such as FDA 21 CFR Part 11 or EU Annex 11) and ensuring that validation activities are harmonized across different systems can be demanding. Strong project management skills, proactive communication with cross-functional stakeholders, and meticulous attention to detail are essential for overcoming these challenges and maintaining audit-ready documentation.
More about Senior Csv Engineer jobs
What cities are hiring for Senior Csv Engineer jobs? Cities with the most Senior Csv Engineer job openings:
What are the most commonly searched types of Csv Engineer jobs? The most popular types of Csv Engineer jobs are:
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Senior Csv Engineer jobs near you
Infographic showing various Senior Csv Engineer job openings in the United States as of June 2026, with employment types broken down into 71% Full Time, and 29% Contract. Highlights an 100% In-person job distribution, with an average salary of $126,557 per year, or $60.8 per hour.
Senior Computer Systems Validation Engineer

Senior Computer Systems Validation Engineer

Vaxcyte

San Carlos, CA • Hybrid

$164K - $190K/yr

Other

Posted 14 days ago

Job description

Summary:

The Senior Computer Systems Validation (CSV) Engineer is responsible for leading validation activities for cloud based GxP systems to ensure they meet regulatory, quality, and operational requirements throughout the system lifecycle. The role focuses on traditional Computer System Validation with application of risk-based Computer Software Assurance (CSA) principles where appropriate.

The individual will work closely with IT and Quality teams to validate and maintain GxP systems across their lifecycle. Strong experience validating relational databases, cloud infrastructure, and integrated applications in regulated biotech or pharmaceutical environments is required.

This is a hands-on role requiring authoring and executing validation documents and protocols for GAMP 5 systems.

This is a hybrid role with minimum of 3 days a week onsite at San Carlos, CA location.

Essential Functions:
  • Hands-on lead full lifecycle Computer System Validation activities for cloud based GxP systems including databases, and applications.
  • Author, update, execute and maintain validation deliverables such as Validation Plans, User Requirements, Functional Specifications, Risk Assessments, Traceability Matrices, IQ, OQ, PQ protocols, and Summary Reports.
  • Perform risk assessments to define validation scope, testing strategy, and documentation requirements in alignment with CSA principles.
  • Define and execute validation strategies for data platforms and system components, ensuring systems meet defined functional, security, and data integrity requirements
  • Assess and validate end to end data flows between upstream source systems and downstream applications to ensure accuracy, completeness, and traceability.
  • Evaluate system changes for validation impact and ensure validated systems remain compliant through appropriate testing and documentation.
  • Ensure validation activities align with automated build and deployment pipelines, confirming that system releases maintain validated state and appropriate validation evidence is generated.
  • Support change control, deviation management, periodic review, and lifecycle management of validated systems.
  • Participate in internal audits and regulatory inspections, providing validation documentation and rationale as required.
  • Contribute to continuous improvement of validation procedures aligned with evolving CSA guidance and cloud delivery models.
Requirements: 
  • Bachelor's degree in Computer Science, Engineering, Life Sciences, or related field, or equivalent professional experience.
  • Minimum 7 years of experience in Computer System Validation within biotech manufacturing and lab data systems. Other combinations of education and/or experience may be considered.
  • Must have technical knowledge of IT infrastructure, software engineering, programming, databases and data integrations.
  • Experience working in modern system environments utilizing CI/CD pipelines or automated release processes.
  • Strong hands-on experience validating GAMP 5 systems for biotech manufacturing.
  • Deep understanding of FDA 21 CFR Part 11, Part 210, Part 211, Annex 11, data integrity requirements, and risk-based validation methodologies.
  • Strong technical writing skills and ability to create comprehensive validation documentation.
  • Ability to communicate validation risks and requirements clearly to IT and Quality stakeholders.

Other combinations of education and/or experience may be considered.

Preferred Qualifications:

  • Hands-on experience validating cloud based GxP systems, specifically Azure.
  • Familiarity with infrastructure as code frameworks like GitHub, Terraform etc.
  • Experience applying CSA principles to custom data applications in GxP cloud.
  • Microsoft Azure or similar technical certifications.
Reports to: Senior Manager, Data Systems
 
Location: San Carlos, CA
 
Work Arrangement: Hybrid (minimum of 3 days per week)
 
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
 
Salary Range: $164,000 - $190,000 (SF Bay Area). Salary ranges for non-California locations may vary.
 
Relocation: 
This role is not eligible for relocation assistance. 
 
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About Vaxcyte

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

51 - 200 Employees

Headquarters location

San Carlos, CA, US

Year founded

2013

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