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Senior Computer Science Bioinformatics Jobs in Houston, TX

Baylor Genetics

AD Scientific Innovation

Houston, TX · On-site

D. in Bioinformatics, Computational Biology, Genetics, Computer Science, Biomedical Engineering, or related field. • 8 years of experience in bioinformatics, computational biology, or genomics. • ...

NABORS

Senior CAD Designer

Houston, TX · On-site

$97K - $104K/yr

The Senior CAD Designer is a key technical contributor within the Engineering team, responsible for ... data science and manufacturing, Nabors aims to innovate the future of energy and enable the ...

Baylor Genetics

Sr HPC Engineer

Houston, TX · On-site

$96K - $132K/yr

JOB SUMMARY We are seeking a Senior HPC Engineer with deep hands-on experience in high-performance ... QUALIFICATIONS • PhD in Bioinformatics, Computational Biology, Computer Science, or related field ...

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$80.7K

$97.7K

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How much do senior computer science bioinformatics jobs pay per year?

As of Aug 13, 2026, the average yearly pay for senior computer science bioinformatics in Houston, TX is $97,666.00, according to ZipRecruiter salary data. Most workers in this role earn between $90,200.00 and $105,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior computer science bioinformatics professional?

To thrive as a Senior Computer Science Bioinformatics professional, you need advanced knowledge in computational biology, programming (such as Python, R, or Java), and a strong background in molecular biology or genomics, often supported by a graduate degree (MSc or PhD). Proficiency with bioinformatics tools (like BLAST, GATK, or Bioconductor), high-performance computing environments, and version control systems (e.g., Git) is essential. Strong problem-solving abilities, analytical thinking, and effective collaboration skills set top performers apart in this field. These competencies are crucial for managing complex biological datasets, developing innovative algorithms, and driving impactful research in interdisciplinary teams.

How does a senior computer science bioinformatics professional typically collaborate with multidisciplinary teams?

Senior Computer Science Bioinformatics professionals often work closely with biologists, clinicians, statisticians, and software engineers to analyze complex biological datasets. They are responsible for translating biological questions into computational problems, developing algorithms or pipelines, and ensuring that results are accurate and actionable. Effective communication and collaboration are essential, as they must bridge the gap between technical and scientific teams, lead project discussions, and sometimes mentor junior team members. This collaborative environment fosters innovation and helps drive research projects or clinical applications forward.

What does a senior computer science bioinformatics professional do?

A Senior Computer Science Bioinformatics professional applies advanced computational methods and software development techniques to analyze biological data, such as DNA, RNA, and protein sequences. They design and implement algorithms, manage large datasets, and collaborate with biologists to interpret results for research or clinical purposes. Their work often supports discoveries in genomics, drug development, and personalized medicine. In addition to technical expertise, they may lead teams, mentor junior staff, and oversee complex projects.

What are the most commonly searched types of Computer Science Bioinformatics jobs in Houston, TX?

The most popular types of Computer Science Bioinformatics jobs in Houston, TX are:

What cities near Houston, TX are hiring for Senior Computer Science Bioinformatics jobs?

Cities near Houston, TX with the most Senior Computer Science Bioinformatics job openings:

Senior Computer Science Bioinformatics jobs near you

Senior Bioinformatics Software Engineer

Morpheus Group

Houston, TX

Full-time

Posted 14 days ago

Job description

We are seeking an experienced Senior/Staff-Level Bioinformatics Software Engineer to provide technical leadership in the design, development, and enhancement of advanced bioinformatics software solutions. This role combines software engineering, computational biology, and data science expertise to support genomic data analysis, next-generation sequencing (NGS) workflows, and the development of scalable analytical platforms.
Key Responsibilities
  • Architect and develop innovative bioinformatics applications, analytical tools, and data processing solutions.
  • Lead the creation and optimization of genomic analysis pipelines focused on sequence interpretation, variant detection, and complex biological data analysis.
  • Partner with scientists, researchers, and cross-functional stakeholders to design studies, analyze results, and translate biological requirements into software solutions.
  • Drive technical strategy and contribute to architectural decisions for current and future software platforms.
  • Improve development processes through automation, best practices, and modern engineering methodologies.
  • Mentor engineering team members and serve as a technical resource across projects. Desired Qualifications
  • Strong background in bioinformatics software development with expertise in NGS data analysis and genomic workflows.
  • Experience working with common bioinformatics formats and tools, including sequencing alignment, variant analysis, and quality control frameworks.
  • Advanced programming skills in Python, R, or similar languages used in scientific computing.
  • Proficiency with Linux environments, cloud computing platforms, and workflow orchestration tools.
  • Experience with software development best practices, source control, testing methodologies, and containerized environments.
  • Excellent communication, leadership, and collaboration skills with the ability to work effectively across scientific and technical teams.

Background
  • Bachelor's degree in Computer Science, Bioinformatics, Data Science, Statistics, Mathematics, or a related field required; advanced degrees preferred.
  • Approximately 7+ years of experience in software engineering, bioinformatics, computational biology, or a related discipline, including demonstrated technical leadership.

This opportunity is ideal for a bioinformatics professional who enjoys leading complex technical initiatives, building scalable genomics solutions, and working at the intersection of software engineering and life sciences