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Senior Bioinformatician Jobs (NOW HIRING)

Insmed Incorporated

About the Role: We're looking for a Senior Scientist, Bioinformatics on the Analytical Development team to help us expand what's possible for patients with serious diseases. Reporting to the Senior ...

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$80.3K

$163.5K

How much do senior bioinformatician jobs pay per year?

As of Aug 15, 2026, the average yearly pay for senior bioinformatician in the United States is $80,287.00, according to ZipRecruiter salary data. Most workers in this role earn between $41,500.00 and $103,000.00 per year, depending on experience, location, and employer.

How does a senior bioinformatician typically collaborate with research teams and other departments?

Senior Bioinformaticians often work closely with multidisciplinary teams, including biologists, data scientists, and software engineers. They play a key role in translating complex biological questions into computational analyses, helping to design experiments and interpret results. Effective communication is crucial, as they must explain analytical approaches and findings to both technical and non-technical stakeholders. Collaboration may also involve mentoring junior team members and coordinating with IT or database management teams to ensure data integrity and accessibility.

What is the difference between Senior Bioinformatician vs Bioinformatics Scientist?

AspectSenior BioinformaticianBioinformatics Scientist
Required CredentialsBachelor's or Master's in Bioinformatics, Biology, or related field; experience in bioinformatics toolsSimilar credentials; often a PhD preferred; strong programming and analytical skills
Work EnvironmentResearch labs, biotech companies, healthcare institutionsAcademic research, biotech firms, pharmaceutical companies
Employer & Industry UsageIndustry-focused, project management, team leadershipResearch-focused, scientific discovery, data analysis

While both roles require expertise in bioinformatics tools and data analysis, a Senior Bioinformatician often has more project management responsibilities and industry experience, whereas a Bioinformatics Scientist may focus more on research and scientific discovery, sometimes with a higher educational requirement like a PhD.

What is a senior bioinformatician?

Senior Bioinformaticians are experienced professionals who analyze and interpret complex biological data, often using computational and statistical techniques. They typically lead bioinformatics projects, develop data analysis pipelines, and collaborate with researchers in areas such as genomics, proteomics, or drug discovery. In addition to technical expertise, they often manage teams, oversee data management, and contribute to scientific publications. Their work is vital in turning raw biological data into actionable insights for research and clinical applications.

What are the key skills and qualifications needed to thrive as a senior bioinformatician, and why are they important?

To thrive as a Senior Bioinformatician, you need advanced expertise in computational biology, programming (such as Python, R, or Perl), and a strong background in genomics or life sciences, usually supported by a master's or PhD. Familiarity with bioinformatics tools, next-generation sequencing (NGS) analysis platforms, high-performance computing, and data visualization software is essential. Strong analytical thinking, problem-solving abilities, and effective communication skills help you collaborate across multidisciplinary teams and translate complex data into actionable insights. These skills are crucial for driving impactful research, ensuring data integrity, and supporting scientific discovery in fast-evolving biomedical environments.
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Senior Bioinformatician jobs near you
Infographic showing various Senior Bioinformatician job openings in the United States as of August 2026, with employment types broken down into 96% Full Time, 2% Part Time, and 2% Contract. Highlights an 87% Physical, 7% Hybrid, and 6% Remote job distribution, with an average salary of $80,287 per year, or $38.6 per hour.

Senior Bioinformaticist - Information Services - Genomics (Hybrid)

Rady Children's Hospital-San Diego

San Diego, CA • Hybrid

$52.95 - $72.81/hr

Full-time

Re-posted 5 days ago

Rady Children's Hospital rating

8.2

Company rating: 8.2 out of 10

Based on 46 frontline employees who took The Breakroom Quiz

98th of 1,059 rated hospitals

Job description

Hybrid role.  

JOB SUMMARY:

The Senior Bioinformaticist is a senior-level individual contributor responsible for helping deploy, maintain, and evolve the bioinformatics framework supporting a high-throughput, ultra-rapid turnaround whole genome sequencing clinical environment. This role focuses primarily on germline genomics pipelines, population genomics analysis, and the continuous improvement of productiongrade bioinformatics workflows.

This position will work as part of a team to build and maintain scalable bioinformatics infrastructure using modern technologies in compute infrastructure, data storage, and genomic analytics, with a strong emphasis on automation, reproducibility, and integration across systems.

In addition to maintaining clinical pipelines, this role will contribute to research and innovation initiatives, exploring new computational approaches, emerging genomic technologies, and AI/ML methods applied to genomic data.

The environment is highly cross-functional, with strong collaboration across clinicians, bioinformaticians, software engineers, and researchers, as well as partnerships with biotechnology companies, academic institutions, and national or international research programs.

MINMUM QUALIFICATIONS:

Master's Degree

Area of study in a field related to the position.

Experience analyzing next-gen sequencing data from raw sequencing output (BCL/FASTQ) through alignment, variant calling, annotation, and prioritization for whole genome or exome sequencing data.

Experience developing, maintaining, and troubleshooting automated bioinformatics pipelines supporting high-throughput genomic analysis in production or research environments.

Experience working with and understanding of NGS analysis tools like Dragen, BWA,, GATK, DeepVariant, Samtools, bcftools, Picard, Annovar, VEP, or similar tools.

Experience with Unix/Linux operating system and software development using any of Ruby, Python, Perl, Bash.

Experience working with large-scale computational environments, including HPC or distributed compute systems, and workflow orchestration tools (e.g., Nextflow, Snakemake, WDL, Cromwell, or similar frameworks). 

PREFERRED QUALIFICATIONS:

Ph.D.

Experience in CNV and SV detection tools and interpretation of complex genomic variation.

Previous experience working in a CAP/CLIA environment.

Previous experience with cloud-based development or analysis and performing benchmarking of bioinformatics tools.

Experience applying machine learning or AI approaches to genomics, phenomics, or biomedical datasets.

Experience analyzing multi-omics datasets, including RNA-seq, long-read sequencing, transcriptomics, proteomics, or related genomic technologies.

The current salary range for this position is $52.95 to $72.81

Rady Children’s Hospital is committed to compensation that is externally competitive and internally equitable. We demonstrate this commitment by conducting regular market reviews to remain competitive with organizations of similar size in the nonprofit, healthcare sector. The range listed above does not represent the full salary range for the position but is the expected hiring range for qualified candidates. Compensation decisions consider a variety of factors including experience, education, licensure, unique skillsets, organizational need, and internal equity. This posting will remain open from the “date posted” until the hiring manager has determined there is a sufficient applicant pool or until the position is filled.

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