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Senior Backend Python Jobs in North Carolina (NOW HIRING)

... as a Senior Backend Software Developer. In this role you will assist in leading projects from ... Strong Python (Flask / SQLAlchemy) experience. * Advanced PostgreSQL database knowledge (e.g ...

Senior Python Developer

Durham, NC · On-site

$117K - $158K/yr

Job Summary The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations ...

Senior Software Engineer - Backend Developer

Raleigh, NC · On-site

$106K - $138K/yr

Senior Software Engineer - Backend Developer Position Requirements: * US Citizenship required ... Go, Rust, and/or Python) * Experience with programming both functional and object orientated ...

Python developer

Charlotte, NC · On-site

$49 - $67.75/hr

Sr Python developer Work Location : Charlotte NC Face to Face interview needed in charlotte NC 12 ... Key Responsibilities: * Design, develop, and maintain backend applications using Python

Python Developer AI/ML

Charlotte, NC · On-site

$49 - $67.75/hr

In this role, you will work closely with Senior Engineers, leads, and product teams to design ... into backend services using REST APIs, GraphQL, or gRPC. • Apply best practices in version ...

Sr. Python Developer

Durham, NC · On-site

$110K - $148K/yr

Job#: 3039740 Sr. Python Developer Location: Durham, North Carolina - Hybrid, 3x per week onsite ... Candidates must have full-stack experience with a strong backend emphasis, including heavy API ...

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Senior Backend Python information

What are the key skills and qualifications needed to thrive as a Senior Backend Python Developer, and why are they important?

To thrive as a Senior Backend Python Developer, you need expertise in Python programming, strong knowledge of backend frameworks (such as Django or Flask), and experience with database management, often backed by a degree in computer science or equivalent experience. Familiarity with version control systems like Git, containerization tools like Docker, cloud platforms (e.g., AWS), and possibly certifications in cloud or Python technologies are common requirements. Outstanding problem-solving skills, effective communication, and the ability to mentor junior developers help set top performers apart. These competencies ensure the development of robust, scalable, and maintainable backend systems that support business objectives.

What is the difference between Senior Backend Python vs Backend Developer?

AspectSenior Backend PythonBackend Developer
Required CredentialsBachelor's in CS or related, 5+ years experience, Python expertiseBachelor's in CS or related, 2-4 years experience, Python knowledge
Work EnvironmentTech companies, startups, enterprise systemsTech firms, startups, software agencies
Employer & Industry UsageUsed across industries requiring scalable backend solutionsCommon in web development and software services
Search & Comparison IntentUnderstanding senior roles, responsibilities, salaryEntry to mid-level backend roles, skill requirements

Senior Backend Python professionals typically have more experience, advanced skills, and leadership responsibilities compared to Backend Developers. They often work on complex systems, mentor junior staff, and have a broader understanding of architecture. Backend Developers focus on building and maintaining backend services with less emphasis on leadership or strategic planning.

What are some common challenges Senior Backend Python developers face when working on large-scale systems?

Senior Backend Python developers working on large-scale systems often encounter challenges such as ensuring application scalability, maintaining code quality across distributed teams, and optimizing performance for high traffic. Balancing the integration of new features with legacy system constraints can also be demanding. Effective communication and collaboration with frontend teams, DevOps, and product managers are crucial for delivering reliable and maintainable backend solutions.

What does a Senior Backend Python Developer do?

A Senior Backend Python Developer designs, builds, and maintains the server-side logic of web applications using Python. They are responsible for creating robust APIs, optimizing databases, ensuring application security, and integrating third-party services. In addition, they often mentor junior developers, contribute to architectural decisions, and collaborate closely with frontend and DevOps teams. Their work ensures that applications are scalable, reliable, and efficient. Senior developers typically have several years of experience and deep knowledge of Python frameworks like Django or Flask.
What are the most commonly searched types of Backend Python jobs in North Carolina? The most popular types of Backend Python jobs in North Carolina are:
What job categories do people searching Senior Backend Python jobs in North Carolina look for? The top searched job categories for Senior Backend Python jobs in North Carolina are:
What cities in North Carolina are hiring for Senior Backend Python jobs? Cities in North Carolina with the most Senior Backend Python job openings:

Senior Backend Engineer (MLOps)

Parser Limited

Davidson, NC

Full-time

Medical

Re-posted 19 hours ago


Job description

Senior Backend Engineer with MLOps


At Parser, we are seeking a Senior Backend Engineer with strong MLOps expertise to join the Engineering team.

In this role, you will help design, build, and maintain the infrastructure that powers ML solutions within the Aircraft Maintenance division-managing data pipelines, streamlining model deployment, and optimizing compute resources.


You'll work on high-impact systems such as predictive maintenance, fault detection, and component lifecycle optimization, while collaborating closely with data scientists and engineering teams to integrate models into production.


Role Overview

We're seeking a passionate and experienced Software Engineer to join the Aircraft Maintenance ML team at our client. This high-impact role combines infrastructure expertise with applied MLOps knowledge, requiring proficiency in software engineering, distributed systems, and machine learning operations.


Key Responsibilities

  • Design and implement scalable ML infrastructure for training, deployment, and serving in batch and real-time environments, supporting aircraft maintenance workflows.
  • Build and maintain efficient data pipelines (ETL/ELT) for large-scale processing and feature engineering, leveraging aircraft sensor, telemetry, and maintenance records data.
  • Optimize compute resources and improve model serving performance across ML systems used in maintenance scheduling and anomaly detection.
  • Implement robust monitoring, logging, and alerting systems, and contribute to MLOps practices including CI/CD pipelines.
  • Collaborate closely with Data Scientists and Maintenance Engineers to streamline the model development-to-production workflow.
  • Research and integrate new technologies, mentor junior engineers, and communicate technical solutions to diverse stakeholders across engineering and operations teams.


Qualifications

  • Bachelor's or Master's degree in Computer Science, Software Engineering, or a related technical field.
  • 6-7 years of experience in Software, Data, or ML engineering roles (preferred).
  • Strong problem-solving skills, proficiency in Python.
  • Understanding of ML algorithms, model architectures, and experience building scalable, reliable ML systems - ideally in safety-critical or regulated industries.
  • Exposure to cloud platforms (e.g., AWS), containerization (Docker), and scalable data systems (e.g., Spark, Kafka).
  • Familiarity with CI/CD tools (e.g., GitHub Actions), ML model serving technologies (e.g., MLflow), and ability to collaborate well across multidisciplinary teams.


Location

  • Madrid: Spain (willingness to travel to the UK 2-3 times a month)


Some of the benefits you'll enjoy working with us:

  • The chance to join an organization with triple-digit growth that is changing the paradigm on how software products are built.
  • The opportunity to form part of an amazing, multicultural community of tech experts.
  • A highly competitive compensation package.
  • Medical insurance.


How to Apply

If you believe you can do the job and are excited to grow with us, we'd love to hear from you. Please submit your application through our careers page.


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