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Senior Backend Python Jobs in North Carolina (NOW HIRING)

Senior Software Engineer - Backend Developer

Raleigh, NC · On-site

$106.50K - $138.40K/yr

Senior Software Engineer - Backend Developer Position Requirements: * US Citizenship required ... Go, Rust, and/or Python) * Experience with programming both functional and object orientated ...

Python developer

Charlotte, NC · On-site

$49 - $67.75/hr

Sr Python developer Work Location : Charlotte NC Face to Face interview needed in charlotte NC 12 ... Key Responsibilities: * Design, develop, and maintain backend applications using Python

Python Developer AI/ML

Charlotte, NC · On-site

$49 - $67.75/hr

In this role, you will work closely with Senior Engineers, leads, and product teams to design ... into backend services using REST APIs, GraphQL, or gRPC. • Apply best practices in version ...

The ideal candidate will work across back-end systems, APIs, and data-driven applications to ... a senior-level role * Proficiency in Python and SQL * Experience with C# * Experience with cloud ...

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Senior Backend Python information

What are the key skills and qualifications needed to thrive as a Senior Backend Python Developer, and why are they important?

To thrive as a Senior Backend Python Developer, you need expertise in Python programming, strong knowledge of backend frameworks (such as Django or Flask), and experience with database management, often backed by a degree in computer science or equivalent experience. Familiarity with version control systems like Git, containerization tools like Docker, cloud platforms (e.g., AWS), and possibly certifications in cloud or Python technologies are common requirements. Outstanding problem-solving skills, effective communication, and the ability to mentor junior developers help set top performers apart. These competencies ensure the development of robust, scalable, and maintainable backend systems that support business objectives.

What are some common challenges Senior Backend Python developers face when working on large-scale systems?

Senior Backend Python developers working on large-scale systems often encounter challenges such as ensuring application scalability, maintaining code quality across distributed teams, and optimizing performance for high traffic. Balancing the integration of new features with legacy system constraints can also be demanding. Effective communication and collaboration with frontend teams, DevOps, and product managers are crucial for delivering reliable and maintainable backend solutions.

What does a Senior Backend Python Developer do?

A Senior Backend Python Developer designs, builds, and maintains the server-side logic of web applications using Python. They are responsible for creating robust APIs, optimizing databases, ensuring application security, and integrating third-party services. In addition, they often mentor junior developers, contribute to architectural decisions, and collaborate closely with frontend and DevOps teams. Their work ensures that applications are scalable, reliable, and efficient. Senior developers typically have several years of experience and deep knowledge of Python frameworks like Django or Flask.

What is the difference between Senior Backend Python vs Backend Developer?

AspectSenior Backend PythonBackend Developer
Required CredentialsBachelor's in CS or related, 5+ years experience, Python expertiseBachelor's in CS or related, 2-4 years experience, Python knowledge
Work EnvironmentTech companies, startups, enterprise systemsTech firms, startups, software agencies
Employer & Industry UsageUsed across industries requiring scalable backend solutionsCommon in web development and software services
Search & Comparison IntentUnderstanding senior roles, responsibilities, salaryEntry to mid-level backend roles, skill requirements

Senior Backend Python professionals typically have more experience, advanced skills, and leadership responsibilities compared to Backend Developers. They often work on complex systems, mentor junior staff, and have a broader understanding of architecture. Backend Developers focus on building and maintaining backend services with less emphasis on leadership or strategic planning.

What are the most commonly searched types of Backend Python jobs in North Carolina? The most popular types of Backend Python jobs in North Carolina are:
What cities in North Carolina are hiring for Senior Backend Python jobs? Cities in North Carolina with the most Senior Backend Python job openings:
Infographic showing various Senior Backend Python job openings in North Carolina as of May 2026, with employment types broken down into 80% Full Time, 18% Part Time, and 2% Contract. Highlights an 91% Physical, and 9% Remote job distribution.

Senior Backend Engineer (Python + MLOps)

Parser Limited

Davidson, NC • Hybrid

Full-time

Medical

Posted 15 days ago


Job description

We are seeking a Senior Backend Engineer with strong MLOps expertise to join the Machine Learning Engineering team of a global leader in the travel industry. In this role, you will help design, build, and maintain the infrastructure that powers our ML solutions managing data pipelines, streamlining model deployment, and optimizing compute resources.


You'll work on high-impact systems such as ranking, recommendation, and pricing optimization, while collaborating closely with data scientists to integrate models into production.


Key Responsibilities

  • Design and implement scalable ML infrastructure for training, deployment, and serving in
    batch and real-time environments.
  • Build and maintain efficient data pipelines for large-scale processing and feature engineering.
  • Optimize compute resources and improve model serving performance across ML systems.
  • Implement robust monitoring, logging, and alerting systems, and contribute to ML Ops
    practices including CI/CD pipelines.
  • Collaborate closely with Data scientists to streamline the model development-to-productionworkflow.
  • Research and integrate new technologies, mentor junior engineers, and communicate
    technical solutions to diverse stakeholders.


Qualifications

  • Bachelors or Masters degree in Computer Science, Software Engineering, or a related technical field.
  • 6-7 years of experience in Software, Data, or ML engineering roles (preferred).
  • Strong problem-solving skills, proficiency in Java and desirable Python.
  • Understanding of ML algorithms, model architectures, and experience building scalable,
    reliable ML systems.
  • Exposure to cloud platforms (e.g., AWS), containerization (Docker), and scalable data
    systems (e.g., Spark, Kafka).
  • Familiarity with CI/CD tools (e.g., GitHub Actions), ML model serving technologies (e.g.,
    MLflow), and ability to collaborate well across teams.


Ideal Candidate


  • This role is well-suited to someone with a solid foundation in at least one of the following areas:software engineering, data engineering, distributed systems, or applied machine learning and areadiness to grow into others as the work requires. We welcome candidates who are strong,language-agnostic problem solvers and passionate about building robust ML systems.


Location


  • Madrid: Hybrid work model with an expected office presence of 3 days per week.


Some of the benefits you'll enjoy working with us:


  • The chance to join an organization with triple-digit growth that is changing the paradigm on how software products are built.
  • The opportunity to form part of an amazing, multicultural community of tech experts.
  • A highly competitive compensation package.
  • Medical insurance.


How to Apply


If you believe you can do the job and are excited to grow with us, we'd love to hear from you. Please submit your application through our careers page.


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