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Senior Backend Python Jobs in California (NOW HIRING)

Genesis10

Senior Backend Engineer

San Francisco, CA · On-site

Genesis10 is currently seeking a Senior Backend Engineer for a contract position with a Global ... Golang or Python (preferred over Java) • Strong experience with Kubernetes or OpenShift for ...

Hedra

Senior Backend Engineer

San Francisco, CA · On-site

... seeking a Senior Backend Engineer. The role involves designing and deploying backend services ... Required : • Experience developing scalable services using Python, using frameworks such as ...

Hedra

Senior Backend Engineer

San Francisco, CA · On-site

$175K - $275K/yr

As a Senior Backend Engineer , you will design, build, and deploy the backend services that power ... Experience developing scalable services using Python, using frameworks such as FastAPI and Pydantic

Phonely Ltd

Senior Backend Engineer

San Francisco, CA · On-site

$200K - $350K/yr

Senior Backend Engineer (Python) At some point in the future, every business will answer their phone with voice AI. We are making sure that when they build that AI agent, the experience of doing so ...

Addison Group

Sr. Backend Engineer

San Ramon, CA · On-site

$65 - $75/hr

Title : Sr. Backend Engineer Location : San Ramon, CA Pay : $65-75/hr Job Type : 6 Month Contract ... React, TypeScript • Backend: o Python (API platform, AWS Lambda, dynamic DBs) o Node.js, ...

Addison Group

Sr. Backend Engineer

San Ramon, CA

$65 - $75/hr

Title : Sr. Backend Engineer Location : San Ramon, CA Pay : $65-75/hr Job Type : 6 Month Contract ... React, TypeScript · Backend: o Python (API platform, AWS Lambda, dynamic DBs) o Node.js, ...

Genesis10

Senior Backend Engineer

San Francisco, CA · On-site

Genesis10 is currently seeking a Senior Backend Engineer for a contract position with a Global ... or Python (preferred over Java) • Experience with containerization technologies such as ...

FlexAI

Senior Backend Engineer

Santa Clara, CA · On-site

$180K - $225K/yr

As a Senior Backend Engineer , you'll drive backend architecture, scale platform services, and ... Golang (Primary), Python (Secondary) * Infrastructure: Kubernetes, Docker, Cloud (AWS/GCP/Azure)

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Senior Backend Python information

What are the key skills and qualifications needed to thrive as a Senior Backend Python Developer, and why are they important?

To thrive as a Senior Backend Python Developer, you need expertise in Python programming, strong knowledge of backend frameworks (such as Django or Flask), and experience with database management, often backed by a degree in computer science or equivalent experience. Familiarity with version control systems like Git, containerization tools like Docker, cloud platforms (e.g., AWS), and possibly certifications in cloud or Python technologies are common requirements. Outstanding problem-solving skills, effective communication, and the ability to mentor junior developers help set top performers apart. These competencies ensure the development of robust, scalable, and maintainable backend systems that support business objectives.

Which pays more, C++ or Python?

For a Senior Backend Python developer, C++ developers often earn higher salaries due to the complexity and performance demands of C++ in systems programming and high-performance applications. However, Python skills are highly in demand for backend development, data science, and automation, which can also lead to competitive compensation. Salary differences depend on industry, experience, and location, but both languages offer strong earning potential in tech roles.

What is the difference between Senior Backend Python vs Backend Developer?

AspectSenior Backend PythonBackend Developer
Required CredentialsBachelor's in CS or related, 5+ years experience, Python expertiseBachelor's in CS or related, 2-4 years experience, Python knowledge
Work EnvironmentTech companies, startups, enterprise systemsTech firms, startups, software agencies
Employer & Industry UsageUsed across industries requiring scalable backend solutionsCommon in web development and software services
Search & Comparison IntentUnderstanding senior roles, responsibilities, salaryEntry to mid-level backend roles, skill requirements

Senior Backend Python professionals typically have more experience, advanced skills, and leadership responsibilities compared to Backend Developers. They often work on complex systems, mentor junior staff, and have a broader understanding of architecture. Backend Developers focus on building and maintaining backend services with less emphasis on leadership or strategic planning.

What are some common challenges Senior Backend Python developers face when working on large-scale systems?

Senior Backend Python developers working on large-scale systems often encounter challenges such as ensuring application scalability, maintaining code quality across distributed teams, and optimizing performance for high traffic. Balancing the integration of new features with legacy system constraints can also be demanding. Effective communication and collaboration with frontend teams, DevOps, and product managers are crucial for delivering reliable and maintainable backend solutions.

What does a Senior Backend Python Developer do?

A Senior Backend Python Developer designs, builds, and maintains the server-side logic of web applications using Python. They are responsible for creating robust APIs, optimizing databases, ensuring application security, and integrating third-party services. In addition, they often mentor junior developers, contribute to architectural decisions, and collaborate closely with frontend and DevOps teams. Their work ensures that applications are scalable, reliable, and efficient. Senior developers typically have several years of experience and deep knowledge of Python frameworks like Django or Flask.

What is the highest paying job in Python?

The highest paying Python-related roles are typically senior positions such as Lead Developer, Solutions Architect, or Machine Learning Engineer, especially in industries like finance, tech, and data science. These roles often require advanced skills, experience, and knowledge of frameworks, cloud platforms, and data management, with salaries exceeding $150,000 annually in many regions.

Is Python in demand for backend?

Python is highly in demand for backend development due to its simplicity, versatility, and extensive libraries like Django and Flask. Many companies seek backend developers skilled in Python to build scalable and efficient web applications, making it a valuable skill for backend roles.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often have expertise in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.
What are the most commonly searched types of Backend Python jobs in California? The most popular types of Backend Python jobs in California are:
What are popular job titles related to Senior Backend Python jobs in California? For Senior Backend Python jobs in California, the most frequently searched job titles are:
What job categories do people searching Senior Backend Python jobs in California look for? The top searched job categories for Senior Backend Python jobs in California are:
What cities in California are hiring for Senior Backend Python jobs? Cities in California with the most Senior Backend Python job openings:
Senior Backend Python jobs near you

Senior Software Engineer (Backend)

Onos Health

San Francisco, CA

Other

Medical, Dental, Vision, Retirement, PTO

Posted 11 days ago

Job description

Senior Backend Engineer

We're seeking an experienced Senior Backend Engineer who is motivated to meaningfully improve the way healthcare is administered in the United States. You'll take ownership in helping develop a significant part of the Onos platform through hands-on development. This role is a hybrid role based in San Francisco, where you'll be expected to work at our office in person 2-3 times a week.

What you'll be doing at Onos:

  • Architect workflows that utilize AI/ML to process claims, medical records and other data types to evaluate the optimal care path for health plan members
  • Lead the integration and rollout of the Onos platform for new enterprise customers to provide actionable insights and recommendations to health plan administrators
  • Own end-to-end development of new features and functionality for the Onos platform, including requirements gathering, scoping, architecting, implementation and testing to deliver timely and high quality outcomes
  • Establish engineering best practices and technical foundations for future team growth
  • Shape our technical roadmap, make key architectural decisions, and influence the company's product and technical strategy

Technical Challenges At Onos:

  • Develop an intelligent engine that ingests complex medical standards of care documents and evaluates provider adherence to guidelines
  • Design and implement robust and extensible systems to easily support many different kinds of enterprise workflows and integrations
  • Build AI/ML pipelines to analyze handwritten clinical notes, accurately extract important medical information, and automate recommendations for clinical reviewers
  • Scale our systems to process millions of healthcare records while maintaining strict security and compliance requirements

Tech Stack:

  • Infrastructure/Systems: AWS (ECS, Bedrock, Glue, etc.), Docker, Github Actions, Terraform
  • Languages/Frameworks:
    • Backend: Python, Django, Celery / Celery Beat, django-ninja, django-tenants
    • Frontend: NextJS, Typescript, Tanstack Query, Shadcn UI, Zod, Nuqs
  • Database/Storage: PostgreSQL (AWS RDS), S3, Clickhouse
  • Development Tools: Github, Jira, Claude Code, CoderabbitAI, Tusk

What we're looking for:

  • 5+ years experience building software applications
  • Prior experience leading engineering teams as a tech lead or engineering manager
  • Strong product sense and system design skills with a track record of defining clear requirements, test scenarios, and acceptance criteria for complex systems
  • Customer obsessed and motivated to make an impact in the healthcare space
  • A hands-on technical leader who can architect robust and extensible systems, establish best practices with AI coding tools, and ship high quality production code

Bonus points if you have:

  • Worked with machine learning and large language models for end-user applications
  • Hands-on experience navigating healthcare data formats such as EDI X12, HL7, FHIR, and custom payer flat files

Benefits and Perks:

  • Flexible hybrid arrangement: 2-3 days/week at San Francisco office (Financial District), remote-first culture
  • Unlimited vacation policy
  • Paid parental leave
  • Medical, dental, and vision insurance
  • Pre-tax commuter benefits
  • 401(k)
  • Significant equity as an early employee
  • Direct mentorship from experienced founders
  • Ground-floor opportunity to help build a team and culture
  • Regular team events and offsites
  • Company-provided equipment and home office setup

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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