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Scientist Translational Pathology Jobs (NOW HIRING)

Moffitt

ASSOC MBR TRANSLATIONAL PATHOLOGY

Long Beach, CA · On-site

$219K - $271K/yr

The Translational Pathology Associate Faculty Member conducts research that is closely aligned and ... D., in a scientific field of study that is of relevance to cancer research. In Lieu of PhD, MD/DO ...

TCWGlobal

Translational Biology Scientist

San Diego, CA · On-site

$54.48/hr

Translational Biology Scientist Temp Pay Rate: Up to $54.48/hour Duration: 12-Month Contract Hours ... Perform quantitative image analysis using digital pathology software such as HALO, QuPath, ImageJ ...

TCWGlobal

Translational Biology Scientist

San Diego, CA

$54.48/hr

Translational Biology Scientist Temp Pay Rate: Up to $54.48/hour Duration: 12-Month Contract Hours ... Perform quantitative image analysis using digital pathology software such as HALO, QuPath, ImageJ ...

Rancho BioSciences

NY · On-site

... through translational research. Our teams of scientists, data engineers, and software experts ... About the role We are seeking an experienced Pathology Research Scientist to join us on a ...

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Scientist Translational Pathology information

What is a scientist translational pathology?

Scientist translational pathology are professionals who bridge the gap between basic scientific research and clinical medicine, focusing on understanding disease mechanisms at the molecular and cellular levels. They work to translate laboratory discoveries into diagnostic tools, treatments, and therapies that can be used in clinical practice. Their work often involves analyzing tissue samples, developing biomarkers, and collaborating with clinicians and researchers to improve patient care. They play a critical role in advancing personalized medicine and enhancing our understanding of disease progression.

How does a scientist translational pathology typically collaborate with clinical and research teams during drug development projects?

A Scientist in Translational Pathology plays a key role in bridging preclinical research and clinical application by working closely with both laboratory scientists and clinical staff. They often participate in multi-disciplinary project teams, providing expertise on tissue-based assays, biomarker identification, and interpretation of pathological findings. Regular interactions with clinicians and researchers ensure that laboratory discoveries are effectively translated into clinical strategies, such as patient stratification or therapeutic response monitoring. This collaborative environment fosters continuous learning and contributes to the advancement of personalized medicine.

What are the key skills and qualifications needed to thrive as a scientist translational pathology, and why are they important?

To thrive as a Scientist Translational Pathology, you need a strong background in pathology, molecular biology, and translational research, typically supported by a PhD or MD and relevant laboratory experience. Familiarity with immunohistochemistry, digital pathology platforms, and data analysis tools is essential, along with experience in handling clinical specimens and regulatory compliance. Critical thinking, attention to detail, and effective collaboration skills help you interpret complex data and work seamlessly with multidisciplinary teams. These competencies are vital for bridging laboratory discoveries and clinical applications, ultimately advancing patient care and therapeutic development.

What is the difference between Scientist Translational Pathology vs Scientist Pathology?

AspectScientist Translational PathologyScientist Pathology
CredentialsTypically requires a PhD in pathology, biomedical sciences, or related fieldsRequires a PhD or MD with specialization in pathology or related areas
Work EnvironmentResearch labs, clinical research settings, biotech or pharma companiesHospitals, diagnostic labs, research institutions
Employer & IndustryBiotech, pharmaceutical, academic researchMedical hospitals, diagnostic laboratories, academic institutions

Scientist Translational Pathology focuses on applying research findings to develop new diagnostics and therapies, bridging laboratory research and clinical application. Scientist Pathology primarily involves diagnosing diseases through tissue analysis and supporting clinical diagnostics. While both roles require advanced degrees and work in research or clinical settings, their core focus differs: translational research versus diagnostic pathology.

What are popular job titles related to Scientist Translational Pathology jobs?

For Scientist Translational Pathology jobs, the most frequently searched job titles are:

Infographic showing various Scientist Translational Pathology job openings in the United States as of September 2026, with employment types broken down into 95% Full Time, and 5% Part Time. Highlights an 95% In-person, and 5% Remote job distribution.

Senior Scientist II - Translational Pathologist

Rockville, MD • On-site

MacroGenics, Inc.
Biotechnology Research and Development • 201 - 500 employees
Learn more about MacroGenics, Inc.external

$126K - $192K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 28 days ago

Job description

MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of 350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceutical and biotechnology companies around the globe.
The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.
Summary of Position:
This position is not impacted by the business announcement issued on May 11, 2026 and will remain with MacroGenics. Please refer to the company press release for additional information: https://ir.macrogenics.com/news-releases/news-release-details/macrogenics-sell-gmp-manufacturing-operations-bora
The Senior Scientist II - Translational Pathologist will support tissue-based pathology activities across MacroGenics' antibody-drug conjugate (ADC) and immunotherapy programs from discovery through IND-enabling studies and early clinical development. This role is responsible for execution of day-to-day histopathologic and biomarker pathology activities, including slide review, assay support, digital pathology analysis, and coordination with external CROs.
The position will work closely with the Senior Director of Pathology and cross-functional team members to deliver high-quality pathology data that informs target selection, translational strategy, safety assessment, and development decisions. Scientific and regulatory accountability remains with senior pathology leadership.
Responsibilities and Job Duties
Preclinical & Translational Pathology
  • Perform necropsy and primary histopathologic assessment of tissues from in vivo pharmacology studies, including H&E, IHC, and multiplex immunofluorescence.
  • Conduct first-pass assessment of target expression, on-target/off-tumor findings, ADC payload-related tissue injury, and tumor-immune microenvironment features relevant to immunotherapy programs.
  • Prepare draft pathology interpretations, figures, and written summaries for internal review and program discussions.

Biomarker & Assay Support
  • Execute pathology components of translational biomarker strategies as defined by senior Pathology and Translational Medicine leadership.
  • Support development, optimization, and validation of single plex IHC and multiplex IHC and IF assays.
  • Perform tissue annotation and support development and optimization of digital pathology and image analysis algorithms under the guidance of the Senior Director of Pathology.
  • Contribute pathology data and figures to internal reports, study summaries, and regulatory-supporting documentation.
  • Coordinate biomarker assay development and validation with CROs.

Documentation & Data Stewardship
  • Draft pathology sections for study reports, slide decks, and internal presentations.
  • Maintain pathology image libraries, annotations, and reference materials.
  • Support development and maintenance of pathology-related SOPs, templates, and best practices.

Cross-Functional Collaboration
  • Present pathology findings in internal project team meetings.
  • Escalate and communicate complex findings, safety signals, or interpretation questions to the Translational Medicine leadership.

Minimum Qualifications
Education & Experience
  • MD, DVM, or PhD with formal training in pathology, histopathology, or a closely related discipline.
  • 3-5 years of experience in biomarker target validation, translational research, biotechnology, pharmaceutical, or CRO environments.

Skills & Abilities
  • Hands-on experience with histopathologic and immunohistochemical tissue evaluation.
  • Excellent pathology diagnostic skills.
  • Skilled in mIF development, validation and spatial analysis.
  • Experience with digital pathology and image analysis platforms (e.g., HALO, QuPath).
  • Strong scientific writing and communication skills.

Preferred Qualifications
  • MD/DVM strongly preferred.
  • Experience supporting ADC, immuno-oncology, or T-cell engager programs.
  • Experience working with AI/ML algorithms for digital pathology analysis.
  • Exposure to GLP toxicology studies and nonclinical safety assessments.
  • Experience working with external CROs.

Additional Information
The annual rate of pay for the Senior Scientist II position ranges from $126,200-192,500. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits.
The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law.
Statement
MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.
Equal Opportunity Employer/Veterans/Disabled
We do not accept non-solicited resumes or candidate submittals from search/recruiting agencies.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.

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