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Scientific Software Jobs (NOW HIRING)

Cadence Design Systems Inc.

$101K - $188K/yr

OpenEye, Cadence Molecular Sciences - a division of Cadence Design Systems - is an industry leader in computational molecular design through rapid, robust, and scalable software, consulting services ...

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How much do scientific software jobs pay per year?

As of Jul 10, 2026, the average yearly pay for scientific software in the United States is $102,500.00, according to ZipRecruiter salary data. Most workers in this role earn between $90,000.00 and $115,000.00 per year, depending on experience, location, and employer.

How does a Scientific Software professional typically collaborate with domain scientists and research teams?

Scientific Software professionals often work closely with domain scientists, researchers, and data analysts to develop and maintain tools that enable scientific discovery. Collaboration usually involves requirements gathering, iterative feedback on prototypes, and integrating scientific algorithms into user-friendly applications. Effective communication skills are crucial, as you’ll be translating complex scientific needs into robust, efficient code and ensuring the software meets both research objectives and usability standards. Team environments tend to be interdisciplinary, offering the opportunity to learn from experts in various scientific fields while contributing your technical expertise.

What are the key skills and qualifications needed to thrive in Scientific Software roles, and why are they important?

To excel in Scientific Software roles, you need a strong background in computer science, mathematics, or a scientific discipline, along with demonstrated programming proficiency (often in Python, C++, or MATLAB). Familiarity with version control systems (like Git), scientific computing libraries, and sometimes specialized tools (e.g., HPC clusters or cloud platforms) is typically expected. Strong analytical thinking, problem-solving, and effective communication skills help bridge the gap between scientific users and technical implementation. These skills ensure the creation of robust, efficient, and user-friendly software that accelerates scientific research and discovery.

What is a scientific software developer?

A scientific software developer is a professional who designs, creates, and maintains software tools and applications used for scientific research and data analysis. These developers work closely with scientists and researchers to translate complex scientific problems into computational solutions. Their work often involves programming, algorithm development, and optimizing code for high-performance computing environments. Scientific software developers play a critical role in fields like physics, biology, chemistry, and engineering by enabling researchers to process and visualize large datasets, simulate experiments, and gain insights from data.

What is the difference between Scientific Software vs Data Analyst?

AspectScientific SoftwareData Analyst
Required CredentialsTypically requires degrees in science, engineering, or computer science; coding skillsUsually requires degrees in statistics, mathematics, or related fields; strong analytical skills
Work EnvironmentResearch labs, scientific institutions, academia, industry R&DBusiness, finance, healthcare, marketing sectors
Employer & Industry UsageUsed by scientists and engineers for simulations, modeling, data analysisUsed by companies for data interpretation, reporting, decision-making

Scientific Software professionals focus on developing and utilizing specialized tools for scientific research and simulations, often working in research environments. Data Analysts interpret data to inform business decisions across various industries. While both roles require analytical skills and familiarity with data, Scientific Software roles emphasize scientific computing and programming, whereas Data Analysts focus on data interpretation and visualization.

More about Scientific Software jobs
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What states have the most Scientific Software jobs? States with the most job openings for Scientific Software jobs include:
What job categories do people searching Scientific Software jobs look for? The top searched job categories for Scientific Software jobs are:
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Scientific Software Developer II - Modeler

Scientific Software Developer II - Modeler

Cadence Design Systems Inc.

On-site, Remote

$101K - $188K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 23 days ago

Job description

At Cadence, we hire and develop leaders and innovators who want to make an impact on the world of technology.

OpenEye, Cadence Molecular Sciences- a division of Cadence Design Systems - is an industry leader in computational molecular design through rapid, robust, and scalable software, consulting services, and Orion, the only cloud-native fully integrated software-as-a-service molecular modeling platform. Combining unlimited computation and storage with powerful tools for data sharing, visualization and analysis in a customizable development platform, Orion offers unprecedented capabilities for the advancement of pharmaceuticals, biologics, agrochemicals, and flavors and fragrances.

We are looking for a Computational Chemist/Cheminformatician to join our team of experts in mathematics, computational modeling, and medicinal chemistry. This highly focused team will work together to drive forward technology which leverages OpenEye's Orion platform to better enable scientists in the pharmaceutical industry working on projects from lead development to clinical candidate selection. This role will require interactions with customers and OpenEye's scientific and technical teams.

What you'll do:

  • Extend OpenEye's programming toolkits by developing and implementing new and useful scientific and technical features to aid customers in developing bespoke solutions.
  • Explore methods for further enhancing OpenEye's virtual screening platform (including OMEGA, ROCS, FastROCS, ROCS X, OEDocking).
  • Apply chemistry/cheminformatics expertise with ML experts to build robust, scalable models to support data-driven decision making.
  • Work on retrospective and prospective projects both internally and with collaborators to validate methodologies.
  • Work with Orion project team to further optimize compound design workflows in Orion.

What you should have:

  • PhD (or equivalent experience) in computational chemistry, chemistry, cheminformatics, or related field with 0 - 3 years relevant experience
  • Knowledge of some traditional computational chemistry approaches such as docking, virtual screening, molecular modeling, etc.
  • Programming expertise, ideally in c++ and/or python preferably with experience using AI coding agents
  • Experience in or desire to learn about the pharmaceutical industry
  • Strong desire to find practical solutions to challenging problems
  • Demonstrated ability to work both as part of a team and independently

The following are a PLUS, but not required:

  • Experience with OpenEye software/toolkits
  • Experience with synthetically accessible, pharmaceutically relevant generative chemistry

The annual salary range for Massachusetts is $101,500 to $188,500. You may also be eligible to receive incentive compensation: bonus, equity, and benefits. Sales positions generally offer a competitive On Target Earnings (OTE) incentive compensation structure. Please note that the salary range is a guideline and compensation may vary based on factors such as qualifications, skill level, competencies and work location. Our benefits programs include: paid vacation and paid holidays, 401(k) plan with employer match, employee stock purchase plan, a variety of medical, dental and vision plan options, and more.

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