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Research Associate Downstream Process Development Jobs in Frederick, MD

System One

Research Associate

Rockville, MD · On-site

$28 - $43/hr

... the R&D of cancer treatment therapies! Responsibilities * Assay and Data Management: Perform ... Prepare and process samples for cytometric analysis. * Dosing Formulations and Reporting: Prepare ...

System One

Research Associate

Rockville, MD · On-site

$28 - $43/hr

... the R&D of cancer treatment therapies! Responsibilities * Assay and Data Management: Perform ... Prepare and process samples for cytometric analysis. * Dosing Formulations and Reporting: Prepare ...

GAP Solutions, Inc

Biologist (50849)

Gaithersburg, MD · On-site

$92K - $102K/yr

Develop downstream (purification) processes, under the supervision of a project lead scientist, for ... process development of clinical trial vaccine candidates and mAb products. * Purify research-phase ...

GAP SOLUTIONS INC

Biologist (50849)

Gaithersburg, MD · On-site

Develop downstream (purification) processes, under the supervision of a project lead scientist, for ... process development of clinical trial vaccine candidates and mAb products. * Purify research-phase ...

MSD

Research Associate

Gaithersburg, MD · On-site

$59K - $87K/yr

This is a laboratory-based position responsible for advancing research and/or development ... processing/aliquotting/vialing/labeling materials, and preparing and maintaining reagent ...

MSD

Research Associate

Gaithersburg, MD · On-site

$59K - $87K/yr

This is a laboratory-based position responsible for advancing research and/or development ... processing/aliquotting/vialing/labeling materials, and preparing and maintaining reagent ...

MSD

Research Associate

Gaithersburg, MD · On-site

$59K - $87K/yr

This is a laboratory-based position responsible for advancing research and/or development ... processing/aliquotting/vialing/labeling materials, and preparing and maintaining reagent ...

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All JobsResearch Associate Downstream Process Development JobsResearch Associate Downstream Process Development Jobs in Frederick, MD

Research Associate Downstream Process Development information

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$33

$49

How much do research associate downstream process development jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for research associate downstream process development in Frederick, MD is $33.49, according to ZipRecruiter salary data. Most workers in this role earn between $27.50 and $41.11 per hour, depending on experience, location, and employer.

What is a research associate downstream process development?

A Research Associate in Downstream Process Development works within biotechnology or pharmaceutical companies to optimize and scale up the purification and recovery of biological products, such as proteins or antibodies, after initial production. They focus on processes like filtration, chromatography, and centrifugation to ensure product quality and yield. These professionals design experiments, analyze data, and support the transfer of processes from laboratory scale to manufacturing. Their work is crucial for developing efficient, reproducible, and regulatory-compliant methods for producing biopharmaceuticals.

What are the key skills and qualifications needed to thrive as a research associate in downstream process development?

To thrive as a Research Associate in Downstream Process Development, you need a solid background in biochemistry, molecular biology, or chemical engineering, often demonstrated by a bachelor's or master's degree in a related field. Familiarity with chromatography systems (such as AKTA), filtration technologies, and Good Manufacturing Practice (GMP) standards, along with data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective teamwork and communication abilities help individuals excel in this role. These competencies are crucial for ensuring efficient, scalable purification processes and maintaining product quality in biopharmaceutical development.

What are the typical challenges faced by a research associate in downstream process development, and how can they be addressed?

A Research Associate in Downstream Process Development often encounters challenges such as optimizing purification processes for new biologics, troubleshooting equipment issues, and ensuring scalability from laboratory to production scale. Effective communication with cross-functional teams, such as upstream scientists and analytical specialists, is essential to resolve issues quickly. Staying current with new purification technologies and maintaining meticulous documentation can also help address these challenges and support successful process development.

What is the difference between Research Associate Downstream Process Development vs Research Associate Upstream Process Development?

AspectResearch Associate Downstream Process DevelopmentResearch Associate Upstream Process Development
Primary FocusPurification, filtration, chromatography of bioproductsCell culture, media optimization, bioreactor operation
Skills & CertificationsProtein purification, chromatography techniques, GMP complianceCell culture, aseptic techniques, bioreactor handling
Work EnvironmentLaboratory, manufacturing, quality controlLaboratory, bioprocessing facilities
Industry UsageBiopharmaceutical manufacturing, biotech researchBiopharmaceutical development, biotech research

While both roles support bioprocess development, Research Associate Downstream Process Development focuses on purification and filtration of bioproducts, whereas Research Associate Upstream Process Development emphasizes cell culture and bioreactor processes. Understanding these differences helps candidates align their skills with the appropriate role in biopharmaceutical production.

What cities near Frederick, MD are hiring for Research Associate Downstream Process Development jobs?

Cities near Frederick, MD with the most Research Associate Downstream Process Development job openings:

Research Associate Downstream Process Development jobs near you
Infographic showing various Research Associate Downstream Process Development job openings in Frederick, MD as of September 2026, with employment types broken down into 62% Full Time, and 38% Part Time. Highlights an 100% In-person job distribution, with an average salary of $69,659 per year, or $33.5 per hour.

Research Associate

Rockville, MD • On-site

System One
Business Consulting Services • 5 - 10K employees
Learn more about System Oneexternal

$28 - $43/hr

Contractor

Medical, Dental, Vision, Life, Retirement

Re-posted 24 days ago

Job description

Job Title: Research Associate Location: Rockville, MD Type: 6+ month Contract Pay Range: $28.00 - $43.00/hr Hours: Monday-Friday 9AM-5PM

Overview Biopharmaceutical Company is seeking a Research Associate, working with animal modeling to support the R&D of cancer treatment therapies! Responsibilities

  • Assay and Data Management: Perform various assays, tests, and studies related to animal modeling. Calculate and analyze raw data to complete research test results. Collate data, perform statistical analyses using software tools such as Microsoft Office, GraphPad Prism, and R Studio. Maintain detailed notes and log data in computer databases and laboratory notebooks.
  • Mammalian Cell Culture: Oversee all aspects of mammalian cell culture, including media and buffer preparation, culture initiation, propagation, and cryopreservation. Handle primary human cells from commercial and patient sources. Ensure that all cell culture procedures are conducted according to standard operating procedures.
  • Flow Cytometry: Assess target antigen expression using traditional and spectral flow cytometry techniques on various in-vitro and ex-vivo samples. Prepare and process samples for cytometric analysis.
  • Dosing Formulations and Reporting: Prepare dosing formulations for in-vivo studies. Report experimental results to the supervisor and collaborate with investigators. Ensure timely and accurate documentation of experimental protocols and data.
  • Record Keeping and Compliance: Maintain detailed and accurate records of experimental data and procedures in laboratory notebooks. Adhere to standard operating procedures and ensure compliance with all regulatory requirements.

Requirements

  • Bachelor's Degree in Animal Science, Biology, or related science field
  • 2+ years of tissue culture, traditional and spectral flow cytometry, animal handling experience (for imaging) and IVIS imaging
  • Strong computer skills, including proficiency with basic data analysis programs (Microsoft Office, GraphPad Prism, Pristima, etc.) and programming and data analysis (R Studio, Linux, etc.)

System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

#M-3 #LI-GS1 Ref: #558-Scientific

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About System One

Sourced by ZipRecruiter

System One helps employers get work done more efficiently and economically without compromising quality. Over our 35+ year history, we've helped connect thousands of talented people with innovative companies. The excitement of a perfect fit motivates us every single day.

Industry

Business consulting services and recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Pittsburgh, PA, US

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