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Research Associate Downstream Process Development Jobs in Texas

... downstream molecular, imaging and functional analyses, organize and summarize research data ... Submitting a cover letter,CV/Resumetoassistus with the review process. You may upload these ...

... downstream molecular, imaging and functional analyses, organize and summarize research data ... Submitting a cover letter, CV/Resume to assist us with the review process. You may upload these ...

... downstream molecular, imaging and functional analyses, organize and summarize research data ... Submitting a cover letter,CV/Resumetoassistus with the review process. You may upload these ...

Senior BioProcess Engineer

Austin, TX · On-site

$150 - $200/hr

... research team for the process development of unique/diverse microorganisms producing novel products for new applications. * Lead troubleshooting and root cause analysis of upstream and downstream ...

Senior BioProcess Engineer

Austin, TX · On-site

$103K - $142K/yr

... research team for the process development of unique/diverse microorganisms producing novel products for new applications. * Lead troubleshooting and root cause analysis of upstream and downstream ...

Senior BioProcess Engineer

Austin, TX · On-site

$103K - $142K/yr

... research team for the process development of unique/diverse microorganisms producing novel products for new applications. * Lead troubleshooting and root cause analysis of upstream and downstream ...

The Research Associate will contribute to ongoing projects, conduct fermentation experiments as ... Support fermentation process development and optimization * Evaluate media composition and feeding ...

The Research Associate will contribute to ongoing projects, conduct fermentation experiments as ... Support fermentation process development and optimization * Evaluate media composition and feeding ...

Partner with Research, Engineering, Quality, and Operations to advance development and ... Deep expertise in microbial fermentation and downstream process development, including scale-up ...

Partner with Research, Engineering, Quality, and Operations to advance development and ... Deep expertise in microbial fermentation and downstream process development, including scale-up ...

Director

Austin, TX · On-site

$250/hr

Partner with Research, Engineering, Quality, and Operations to advance development and ... Deep expertise in microbial fermentation and downstream process development, including scale-up ...

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Research Associate Downstream Process Development information

What is a research associate downstream process development?

A Research Associate in Downstream Process Development works within biotechnology or pharmaceutical companies to optimize and scale up the purification and recovery of biological products, such as proteins or antibodies, after initial production. They focus on processes like filtration, chromatography, and centrifugation to ensure product quality and yield. These professionals design experiments, analyze data, and support the transfer of processes from laboratory scale to manufacturing. Their work is crucial for developing efficient, reproducible, and regulatory-compliant methods for producing biopharmaceuticals.

What are the key skills and qualifications needed to thrive as a research associate in downstream process development?

To thrive as a Research Associate in Downstream Process Development, you need a solid background in biochemistry, molecular biology, or chemical engineering, often demonstrated by a bachelor's or master's degree in a related field. Familiarity with chromatography systems (such as AKTA), filtration technologies, and Good Manufacturing Practice (GMP) standards, along with data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective teamwork and communication abilities help individuals excel in this role. These competencies are crucial for ensuring efficient, scalable purification processes and maintaining product quality in biopharmaceutical development.

What are the typical challenges faced by a research associate in downstream process development, and how can they be addressed?

A Research Associate in Downstream Process Development often encounters challenges such as optimizing purification processes for new biologics, troubleshooting equipment issues, and ensuring scalability from laboratory to production scale. Effective communication with cross-functional teams, such as upstream scientists and analytical specialists, is essential to resolve issues quickly. Staying current with new purification technologies and maintaining meticulous documentation can also help address these challenges and support successful process development.

What is the difference between Research Associate Downstream Process Development vs Research Associate Upstream Process Development?

AspectResearch Associate Downstream Process DevelopmentResearch Associate Upstream Process Development
Primary FocusPurification, filtration, chromatography of bioproductsCell culture, media optimization, bioreactor operation
Skills & CertificationsProtein purification, chromatography techniques, GMP complianceCell culture, aseptic techniques, bioreactor handling
Work EnvironmentLaboratory, manufacturing, quality controlLaboratory, bioprocessing facilities
Industry UsageBiopharmaceutical manufacturing, biotech researchBiopharmaceutical development, biotech research

While both roles support bioprocess development, Research Associate Downstream Process Development focuses on purification and filtration of bioproducts, whereas Research Associate Upstream Process Development emphasizes cell culture and bioreactor processes. Understanding these differences helps candidates align their skills with the appropriate role in biopharmaceutical production.

What cities in Texas are hiring for Research Associate Downstream Process Development jobs?

Cities in Texas with the most Research Associate Downstream Process Development job openings:

Research Associate

Houston, TX • On-site

The Texas A&M University System
Colleges, Universities, and Professional Schools • 201 - 500 employees

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 11 days ago


Job description

Job Title
Research Associate
Agency
Texas A&M University Health Science Center
Department
IBT - CGPM - Ramos
Proposed Minimum Salary
Commensurate
Job Location
Houston, Texas
Job Type
Staff
Job Description
Our Commitment
Texas A&M University is committed to enriching the learning and working environment by promoting a culture that respects all perspectives, talents & lived experiences. Embracing varying opinions and perspectives strengthens our core values which are: Respect, Excellence, Leadership, Loyalty, Integrity, and Selfless Service.
Who we are
As one of the fastest-growing academic health centers in the nation, Texas A&M Health encompasses five colleges and numerous centers and institutes working together to improve health through transformative education, innovative research and team-based health care delivery.
What we want
The Research Associate supports projects focused on human pluripotent stem cell (hPSC)-derived airway and lung epithelial models, including region-specific airway basal stem cell and alveolar differentiation, airway and alveolar epithelial maturation, and disease modeling. The Research Associate will conduct cell culture and differentiation experiments, perform downstream molecular, imaging and functional analyses, organize and summarize research data, maintain detailed experimental records, and assist with training students and other laboratory personnel in research techniques and laboratory procedures.
What you need to know
Salary: Will be commensurate based on the selected hire's education and experience.
Location/Schedule: Houston, TX/Full-Time
Apply! Submitting a cover letter, CV/Resume to assist us with the review process. You may upload these documents on the application under CV/Resume.
Responsibilities
Research and Experimental Work
Conduct and coordinate experiments related to human pluripotent stem cell-derived airway and alveolar epithelial differentiation and lung disease modeling. Maintain hPSC and differentiated lung epithelial cultures, perform airway basal cell ALI differentiation and maintenance, flow cytometry, immunostaining, microscopy, qPCR, and other molecular and cellular assays. Assist with animal xenograft model experiments in accordance with approved protocols. Maintain detailed experimental records, organize data, evaluate results, troubleshoot protocols, and assist with laboratory equipment operation and maintenance.
Documentation and Data Analysis
Analyze, interpret, and summarize experimental results from in vitro differentiation experiments and in vivo xenograft studies. Prepare data summaries, figures, and written materials for laboratory meetings and progress reports. Assist with sample tracking, reagent inventory, protocol documentation, data management, and coordination of sequencing, histology, imaging, or core facility submissions. Support documentation for biosafety, stem cell, and animal research protocols as needed.
Training and Laboratory Coordination
Train and assist students and other laboratory personnel in cell culture, differentiation protocols, laboratory techniques, animal study-related sample processing, data organization, safety procedures, and routine laboratory operations. Help establish and maintain standard operating procedures and quality control practices to support reproducible experiments.
Required Education and Experience
  • Bachelor's degree in biology, biomedical sciences, molecular biology, cell biology, or a related field, or an equivalent combination of education and experience.
  • Two years of related research experience in a biomedical research laboratory.

Preferred Qualifications
  • Experience with airway or lung epithelial biology, ALI culture, immunofluorescence staining, microscopy, qPCR, single-cell sequencing sample preparation, and/or animal model support.
  • Prior experience in a stem cell and developmental biology, epithelial biology, or lung disease research laboratory is preferred.

Knowledge, Skills, and Abilities
  • Experience with human pluripotent stem cell maintenance and directed differentiation, flow cytometry, and standard molecular or cell biology techniques
  • Knowledge of mammalian cell culture and molecular/cellular biology techniques.
  • Strong organizational skills and attention to detail.
  • Ability to follow established protocols and troubleshoot experiments.
  • Ability to work independently and collaboratively in a research team.
  • Ability to maintain accurate and timely laboratory records.
  • Ability to analyze, summarize, and communicate research results.
  • Ability to train and support students and other laboratory personnel.
  • Familiarity with biosafety practices, sterile technique, data organization, laboratory inventory management, and animal research compliance requirements.
  • Ability to assist with animal model-related experimental preparation, monitoring, tissue/sample collection, and downstream analysis under approved protocols.

Why Texas A&M University?
We are a prestigious university with strong traditions, Core Values, and a community of caring and collaboration.
  • Medical, prescription drug, dental, vision, life and AD&D, flexible spending accounts, and long-term disability insurance with Texas A&M contributing to employee health and basic life premiums
  • 12-15 days of annual paid holidays
  • Up to eight hours of paid sick leave and at least eight hours of paid vacation each month
  • Automatic enrollment in the Teacher Retirement System of Texas
  • Health and Wellness: Free exercise programs and release time
  • Professional Development: All employees have access to free LinkedIn Learning training, webinars, and limited financial support to attend conferences, workshops, and more
  • Educational release time and tuition assistance for completing a degree while a Texas A&M employee
  • Living Well, a program at Texas A&M that has been built by employees, for employees

Instructions to Applicants: Applications received by Texas A&M University must either have all job application data entered, or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to prepopulate the online application.
All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution's verification of credentials and/or other information required by the institution's procedures, including the completion of the criminal history check.
Equal Opportunity/Veterans/Disability Employer.