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Research Associate Downstream Process Development Jobs in Missouri

ICON

Senior Clinical Research Associate

Kansas City, MO · On-site +1

$110K - $138K/yr

Learning and development opportunities through structured training and career pathways Benefits may ... If you require reasonable accommodations during the recruitment process, please let us know or ...

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Senior Clinical Research Associate

Kansas City, MO · On-site

$110K - $138K/yr

Learning and development opportunities through structured training and career pathways Benefits may ... If you require reasonable accommodations during the recruitment process, please let us know or ...

Jobtailor

Equity Research Associate

California, MO · On-site

Research and analyze companies and related industries * Build financial models and draft reports ... Contribute to the investment process * Work on projects of growing complexity with direction and ...

New

Washington University of St. Louis

... drug development, and advance personalized medicine. The successful candidate will develop ... processing), and the highly collaborative atmosphere at WashU. The candidate is expected to lead ...

Washington University of St. Louis

Design and execute independent research projects focused on antibody engineering, ADC development ... process, please refer to our External Applicant FAQ. Accommodation If you are unable to use our ...

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Research Associate Downstream Process Development information

What is a research associate downstream process development?

A Research Associate in Downstream Process Development works within biotechnology or pharmaceutical companies to optimize and scale up the purification and recovery of biological products, such as proteins or antibodies, after initial production. They focus on processes like filtration, chromatography, and centrifugation to ensure product quality and yield. These professionals design experiments, analyze data, and support the transfer of processes from laboratory scale to manufacturing. Their work is crucial for developing efficient, reproducible, and regulatory-compliant methods for producing biopharmaceuticals.

What are the key skills and qualifications needed to thrive as a research associate in downstream process development?

To thrive as a Research Associate in Downstream Process Development, you need a solid background in biochemistry, molecular biology, or chemical engineering, often demonstrated by a bachelor's or master's degree in a related field. Familiarity with chromatography systems (such as AKTA), filtration technologies, and Good Manufacturing Practice (GMP) standards, along with data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective teamwork and communication abilities help individuals excel in this role. These competencies are crucial for ensuring efficient, scalable purification processes and maintaining product quality in biopharmaceutical development.

What are the typical challenges faced by a research associate in downstream process development, and how can they be addressed?

A Research Associate in Downstream Process Development often encounters challenges such as optimizing purification processes for new biologics, troubleshooting equipment issues, and ensuring scalability from laboratory to production scale. Effective communication with cross-functional teams, such as upstream scientists and analytical specialists, is essential to resolve issues quickly. Staying current with new purification technologies and maintaining meticulous documentation can also help address these challenges and support successful process development.

What is the difference between Research Associate Downstream Process Development vs Research Associate Upstream Process Development?

AspectResearch Associate Downstream Process DevelopmentResearch Associate Upstream Process Development
Primary FocusPurification, filtration, chromatography of bioproductsCell culture, media optimization, bioreactor operation
Skills & CertificationsProtein purification, chromatography techniques, GMP complianceCell culture, aseptic techniques, bioreactor handling
Work EnvironmentLaboratory, manufacturing, quality controlLaboratory, bioprocessing facilities
Industry UsageBiopharmaceutical manufacturing, biotech researchBiopharmaceutical development, biotech research

While both roles support bioprocess development, Research Associate Downstream Process Development focuses on purification and filtration of bioproducts, whereas Research Associate Upstream Process Development emphasizes cell culture and bioreactor processes. Understanding these differences helps candidates align their skills with the appropriate role in biopharmaceutical production.

What cities in Missouri are hiring for Research Associate Downstream Process Development jobs?

Cities in Missouri with the most Research Associate Downstream Process Development job openings:

Research Associate Downstream Process Development jobs near you
Infographic showing various Research Associate Downstream Process Development job openings in Missouri as of August 2026, with employment types broken down into 90% Full Time, and 10% Contract. Highlights an 97% In-person, and 3% Remote job distribution.

Research Associate, Scientific Services

Columbia, MO • On-site

Altasciences
Scientific Research and Development Services • 1 - 5K employees
Learn more about Altasciencesexternal

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 17 days ago

Altasciences rating

7.6

Company rating: 7.6 out of 10

Based on 17 frontline employees who took The Breakroom Quiz

61st of 121 rated laboratories

Job description

About The Role
As a Research Associate (RA), you'll perform technical procedures, restrain animals, operate laboratory equipment, collect specimens, and collects data on laboratory animals (canines, mice, rabbits, rats, non-human primates, swine, etc.) as specified in Protocols and Standard Operating Procedures (SOPs) in compliance with GLP standards. Support Study Supervisor(s) and Study Director(s) by performing and assisting with sample and data collection on research studies.
What You'll Do Here
  • Follow SOPs and Protocols to perform procedures on study and stock animals, including, but not limited to: clinical observations, food consumptions, body weights, urine collection, administering injectable anesthesia, mating procedures, restraint, enrichment, and feeding and food removal.
  • Assist with blood draws, catheter placement, dose administration, and euthanasia.
  • Follow written and verbal instruction: Standard Operating Procedures (SOP), Protocols, Daily Schedules.
  • Record, enters and reviews raw data, study and facility.
  • Sets up for procedures and maintains ancillaries on study animals.
  • Operate selected laboratory equipment (i.e., glucometer, digital thermometer).
  • Monitor and report changes in animal behavior or health, and problems with animal rooms (e.g., caging, lights, and temperature) to all appropriate personnel.
  • Maintain general cleanliness and organization of work areas.
  • Monitor and report study changes to Study Director and all appropriate personnel.
  • Obtain animal information (tattoo, sex, ear tag, ear notch, etc), recognizes animal behavior health status, and reports to appropriate personnel.

What You'll Need to Succeed
  • High School Diploma and/or GED required; BS/BA in a scientific discipline preferred.
  • Minimum of 0-1 of related experience.
  • Knowledge of MS Office suite and the ability to adapt easily to new software programs.
  • Ability to work cross functionally on process improvements.
  • Demonstrated attention to detail and the ability to multi-task and maintain organization in a fast paced, changing environment.
  • Ability to manage change and can readily adapt to new projects.
  • Positive attitude toward work and co-workers.
  • Being comfortable communicating with all levels of management and employees.
  • Able to identify and resolve problems as they are encountered.
  • ALAT certification preferred.

Work Authorization & Sponsorship:
Applicants must be legally authorized to work in the United States. Altasciences is unable to provide sponsorship, sponsorship transfers, or visa maintenance for this position. All applicants must possess valid work authorization that does not require employer sponsorship now or in the future.
What We Offer
Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.
Altasciences' Benefits Package Includes:
  • Health/Dental/Vision Insurance Plans
  • 401(k)/RRSP with Employer Match
  • Paid Vacation and Holidays
  • Paid Sick and Bereavement Leave
  • Employee Assistance & Telehealth Programs
  • Telework when applicable.

Altasciences' Incentive Programs Include:
  • Training & Development Programs
  • Employee Referral Bonus Program

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