Remote Bioinformatics Machine Learning Jobs in Philadelphia, PA

For over 50 years, LexisNexis Reed Technology has partnered with the U.S. Patent and Trademark Office (USPTO) to deliver secure, scalable, and high-quality patent data processing solutions. Our work transforms complex, unstructured patent submissions into standardized, searchable outputs that power examiner workflows and public dissemination.

We operate in a highly regulated environment with strict security requirements, large-scale data volumes, and complex business rules. Our focus is on modernizing legacy workflows through automation, AI, and platform transformation to improve efficiency, accuracy, and cost effectiveness.

About the Role

We are seeking a hands-on Principal AI Engineer who can design and build production-grade AI solutions while growing into a broader AI Architect role. This position is ideal for an experienced AI developer or technical lead who has strong engineering depth, understands modern AI architecture, and is ready to expand their influence across platforms, products, and delivery teams.

The Principal AI Engineer will work closely with product managers, architects, data scientists, software engineers, security teams, and government stakeholders to translate mission and business needs into secure, scalable, and reusable AI capabilities. The role will initially focus on solution design and hands-on implementation, with increasing responsibility for architecture standards, technical strategy, governance, and cross-team alignment.

• You must be a U.S. citizen to apply for this position.

• You must successfully pass a background investigation and achieve Public Trust security clearance.

• Must be located near the Horsham, PA location for a hybrid onsite schedule.

• Design, prototype, and implement AI-powered applications, services, agents, and workflows.
• Translate business, user, and government mission requirements into practical technical solutions.
• Develop solutions using large language models, retrieval-augmented generation, machine learning, natural language processing, computer vision, or other relevant AI technologies.
• Build reusable AI components, services, APIs, evaluation frameworks, and reference implementations.
• Integrate AI capabilities with enterprise platforms, data sources, workflows, and existing applications.
• Balance rapid experimentation with the engineering discipline required for secure, reliable production systems.
• Evaluate models, platforms, frameworks, and vendors based on performance, cost, security, scalability, and mission fit.

• Contribute to solution architectures covering applications, models, data, integrations, infrastructure, security, and operational monitoring.
• Partner with senior architects to establish AI architecture patterns, guardrails, standards, and reference architectures.
• Help teams make informed decisions regarding commercial, open-source, and internally developed AI capabilities.
• Identify opportunities to create shared AI services and reusable capabilities across products, contracts, and government agencies.
• Participate in architecture reviews and clearly document technical decisions, tradeoffs, assumptions, and risks.
• Provide technical guidance, code reviews, mentoring, and hands-on support to engineering and data science teams.
• Grow into ownership of end-to-end AI solution architecture and broader technical strategy.

• Support technical discovery sessions, demonstrations, proofs of concept, proposals, RFIs, and RFP responses.
• Communicate complex AI concepts, limitations, risks, and tradeoffs clearly to both technical and non-technical audiences.
• Help move successful prototypes into secure, supportable, and scalable production capabilities.
• Stay informed about evolving government AI policies, standards, acquisition practices, and responsible-AI expectations.

• Bachelor's degree in computer science, engineering, data science, information systems, or a related field, or equivalent practical experience.
• Significant professional software engineering experience, including experience delivering production applications or platforms.
• Hands-on experience developing AI, machine-learning, or data-intensive solutions.
• Proficiency in Python and experience with APIs, cloud services, data pipelines, software development practices, and source control.
• Experience with modern generative-AI patterns, such as large language models, retrieval-augmented generation, embeddings, vector search, tool use, structured outputs, or AI agents.
• Understanding of cloud-native architecture, system integration, identity and access management, observability, and secure development practices.
• Ability to evaluate technical alternatives and explain architecture decisions and tradeoffs.
• Experience working across product, engineering, data, security, and business teams.
• Strong written and verbal communication skills.
• Ability to satisfy applicable government background, suitability, or contractual requirements.
• Incorporate security, privacy, accessibility, explainability, auditability, and human oversight into solution designs.
• Establish appropriate evaluation methods for accuracy, relevance, groundedness, bias, safety, and reliability.
• Design controls for model and prompt versioning, data lineage, access management, logging, monitoring, and traceability.
• Partner with cybersecurity, legal, privacy, compliance, and governance teams throughout the solution lifecycle.
• Ensure solutions align with applicable organizational policies, contractual obligations, and government requirements.
• Design human-in-the-loop controls based on the risk and impact of the decisions supported or performed by AI.

• Experience delivering technology solutions for U.S. federal, state, or local government customers.
• Experience working in government contracting, regulated environments, or programs involving sensitive data.
• Familiarity with government security and compliance frameworks, such as NIST, FedRAMP, FISMA, or agency-specific controls.
• Experience with one or more major cloud platforms, particularly AWS, Microsoft Azure, or Google Cloud.
• Experience with AI orchestration frameworks, model gateways, vector databases, evaluation platforms, MLOps, or LLMOps.
• Understanding of model evaluation, prompt engineering, fine-tuning, data governance, and responsible-AI practices.
• Experience moving AI proofs of concept into production.
• Experience supporting technical proposals, RFIs, RFPs, solution demonstrations, or customer workshops.
• Prior technical leadership, mentoring, or architecture-review experience.
• Relevant cloud, architecture, security, data, or AI certifications.

We promote a healthy work/life balance across the organisation. We offer an appealing working prospect for our people. With numerous wellbeing initiatives, shared parental leave, study assistance and sabbaticals, we will help you meet your immediate responsibilities and your long-term goals.

• Working flexible hours to help you fit everything in and work when you are the most productive

We know that your wellbeing and happiness are key to a long and successful career. These are some of the benefits we are delighted to offer:

• Health Benefits: Comprehensive, multi-carrier program for medical, dental and vision benefits

• Retirement Benefits: 401(k) with match and an Employee Share Purchase Plan

• Wellbeing: Wellness platform with incentives, Headspace app subscription, Employee Assistance and Time-off Programs

• Short-and-Long Term Disability, Life and Accidental Death Insurance, Critical Illness, and Hospital Indemnity

• Family Benefits, including bonding and family care leaves, adoption and surrogacy benefits

• Health Savings, Health Care, Dependent Care and Commuter Spending Accounts

• Up to two days of paid leave each to participate in Employee Resource Groups and to volunteer with your charity of choice

About the Business

LexisNexis Legal & Professional provides legal, regulatory, and business information and analytics that help customers increase their productivity, improve decision-making, achieve better outcomes, and advance the rule of law around the world. As a digital pioneer, the company was the first to bring legal and business information online with its Lexis and Nexis services.

We know your well-being and happiness are key to a long and successful career. We are delighted to offer country specific benefits. Click here to access benefits specific to your location.

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We are an equal opportunity employer: qualified applicants are considered for and treated during employment without regard to race, color, creed, religion, sex, national origin, citizenship status, disability status, protected veteran status, age, marital status, sexual orientation, gender identity, genetic information, or any other characteristic protected by law.

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