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Python Jobs in San Mateo, CA (NOW HIRING)

ClinDCast LLC

Python Backend Engineer

Sunnyvale, CA · On-site

$60 - $65/hr

We are seeking an experienced Python Backend Engineer to design, develop, and maintain scalable backend systems and APIs. The ideal candidate will have strong expertise in Python, modern backend ...

Floodwave

Python/ Django + SQL Engineer

San Francisco, CA · On-site

$59.25 - $81.50/hr

Python/ Django + SQL Engineer We are looking for top-notch Python/ Django frontend developers with strong skills in HTML(5), CSS and JS. You will work with a team to build an analytics and metrics ...

Programmers.io

Python + ML

Sunnyvale, CA · On-site

$59 - $81.25/hr

Excellent expertise in Object oriented programming Python and API's. * Excellent expertise in AI/ML Technologies * Excellent expertise in Numpy, Pandas, SciPy * Excellent expertise in Tensor Flow ...

Sonsoft Inc

Python Programmer

Redwood City, CA · On-site

Fluent in one programming languages - Python. Experience with JavaScript - Angular, Bootstrap or other frameworks is desired Experience working with distributed systems Team-oriented, with strong ...

Echo IT Solutions

Python AI

Santa Clara, CA · On-site

$164K - $201K/yr

... across Python and .NET platforms. • Review and approve architecture designs, code, and technical documentation. • Identify and drive systemic technical improvements, including reuse ...

Collabera

Python Developer

San Jose, CA

$59 - $81.25/hr

Python Developer with django Qualifications Additional Information To know more on this position, please contact: Renu Dewangan 973-854-9106

Pddn

Python SRE

Redwood City, CA · On-site

$61.50 - $84.75/hr

Python SRE Redwood City, CA Contract Responsibilities: * 3+ years of experience designing, building and implementing server software * Strong coding ability in an object-oriented language (Python ...

Eateam

Sr. Python Developer

Palo Alto, CA

$143K - $192K/yr

Title: Sr. Python Developer Location: Palo Alto CA Duration: Long Term Contract Required Skills :- Python ,Restful API, Django or flask The Skills required to be successful: Experience developing web ...

Jobsbridge

Python Software Developer

San Jose, CA · On-site

$59 - $81.25/hr

Self-directed work style with minimum supervision More than 8 years of experience developing/testing/deploying secure production quality software products Expert level programming (Python, Java) and ...

Jobsbridge

Python Software Developer

San Jose, CA

$59 - $81.25/hr

Self-directed work style with minimum supervision More than 8 years of experience developing/testing/deploying secure production quality software products Expert level programming (Python, Java) and ...

Career Movement

Python Engineer

San Francisco, CA · On-site

Strong coding fundamentals in at least one modern language such as Python, Go, or Rust * Solid understanding of data structures, algorithms, and distributed systems * Familiarity with REST APIs, SQL ...

Career Movement

Python Engineer

San Francisco, CA

Strong coding fundamentals in at least one modern language such as Python, Go, or Rust * Solid understanding of data structures, algorithms, and distributed systems * Familiarity with REST APIs, SQL ...

Jobsbridge

Python Software Developer

San Jose, CA

$59 - $81.25/hr

Self-directed work style with minimum supervision More than 8 years of experience developing/testing/deploying secure production quality software products Expert level programming (Python, Java) and ...

Eateam

Sr. Python Developer

Palo Alto, CA · On-site

$143K - $192K/yr

Company Description Title: Sr. Python Developer Location: Palo Alto CA Duration: Long Term Contract Required Skills :- Python ,Restful API, Django or flask The Skills required to be successful: • ...

1 point system

Python QA Engineer

Fremont, CA · On-site

Onsite round involves whiteboard Python coding Key Responsibilities * Design & execute manual + automated test cases across UI, API, backend * Build & maintain scalable automation frameworks ...

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How much do python jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for python in San Mateo, CA is $66.77, according to ZipRecruiter salary data. Most workers in this role earn between $55.05 and $75.87 per hour, depending on experience, location, and employer.

What are some common challenges Python developers face when working on large-scale projects?

Python developers often encounter challenges such as managing dependencies, ensuring code scalability, and maintaining performance on large-scale projects. Collaboration with cross-functional teams can add complexity, especially when integrating with systems written in other languages. Adopting best practices like modular code structure, thorough documentation, and automated testing can help mitigate these challenges and streamline teamwork.

What is the difference between Python developer vs Java developer?

AspectPython DeveloperJava Developer
Required CredentialsBachelor's in CS or related field, Python certifications (optional)Bachelor's in CS or related field, Java certifications (optional)
Work EnvironmentWeb development, data science, automationEnterprise applications, Android development, backend systems
Industry UsageTech startups, data analysis firms, automation companiesFinancial services, large enterprise software, mobile app companies

Python developers focus on scripting, data analysis, and web development, often working in startups or data-driven fields. Java developers typically work on large-scale enterprise applications and Android apps. While both roles require programming skills and similar educational backgrounds, their industry applications and project types differ significantly.

What is a Python developer?

A Python developer is a software programmer who specializes in writing, testing, and maintaining code using the Python programming language. They can work on a variety of projects, including web development, data analysis, machine learning, automation, and scripting. Python developers often collaborate with other team members to design solutions and ensure the functionality and performance of applications. Their responsibilities may also include debugging programs, integrating third-party services, and writing documentation.

What are the key skills and qualifications needed to thrive as a Python developer?

To thrive as a Python Developer, you need strong programming skills in Python, knowledge of software development principles, and typically a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and experience with databases are highly valued, along with certifications like PCEP or PCAP. Effective problem-solving, communication, and teamwork are essential soft skills to excel in collaborative and dynamic environments. These skills collectively ensure the delivery of robust, maintainable code and efficient project outcomes in technology-driven organizations.

What is Python?

Python is a programming language used to write or develop a variety of programs and applications. The software developer community uses Python for programming because it is a simple language that is easy to test and debug. Large internet companies such as Facebook, Google, Reddit, and Amazon use Python, and so do government agencies such as NASA. Programmer professionals have used Python to help build popular software such as Autodesk Maya and other visual design applications. Financial professionals and stock traders use Python when scripting algorithms for economic predictions or computerized trading.

More about Python jobs

What are the most commonly searched types of Python jobs in San Mateo, CA?

The most popular types of Python jobs in San Mateo, CA are:

What are popular job titles related to Python jobs in San Mateo, CA?

For Python jobs in San Mateo, CA, the most frequently searched job titles are:

What job categories do people searching Python jobs in San Mateo, CA look for?

The top searched job categories for Python jobs in San Mateo, CA are:

What cities near San Mateo, CA are hiring for Python jobs?

Cities near San Mateo, CA with the most Python job openings:

Python jobs near you
Infographic showing various Python job openings in San Mateo, CA as of August 2026, with employment types broken down into 2% Internship, 81% Full Time, 10% Part Time, and 7% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $138,881 per year, or $66.8 per hour.

Python Backend Engineer

ClinDCast LLC

Sunnyvale, CA • On-site

$60 - $65/hr

Full-time

Re-posted 23 days ago

Job description

Job Summary:
We are seeking an experienced Python Backend Engineer to design, develop, and maintain scalable backend systems and APIs. The ideal candidate will have strong expertise in Python, modern backend frameworks, cloud infrastructure, databases, and AI-powered application development. This role offers the opportunity to work on cutting-edge solutions involving AI agents, large language models (LLMs), and high-performance distributed systems.
Key Responsibilities:
Design, develop, and maintain scalable backend applications and APIs using Python.
Build and optimize RESTful APIs using FastAPI, Django, or similar frameworks.
Develop and integrate AI-driven workflows using tools such as LangChain, LlamaIndex, or related frameworks.
Manage database design, performance tuning, and data integrations across SQL and NoSQL environments.
Implement secure authentication and authorization mechanisms, including OAuth2, JWT, and OpenID Connect.
Build and maintain cloud-native applications on AWS or GCP.
Develop asynchronous processing solutions and task orchestration workflows.
Collaborate with cross-functional teams to deliver scalable, reliable, and secure software solutions.
Monitor application performance and ensure system reliability and scalability.
Required Qualifications:
Strong experience in Python development (Python 3.10+ preferred).
Hands-on experience with FastAPI, Django, or similar backend frameworks.
Experience building and consuming REST APIs and microservices.
Knowledge of AI/LLM integration frameworks such as LangChain or LlamaIndex.
Strong experience with PostgreSQL and NoSQL databases such as MongoDB and Redis.
Experience with Vector Databases such as Pinecone, Weaviate, or similar technologies.
Proficiency with Docker and cloud platforms (AWS or GCP).
Experience with asynchronous programming and task queues.
Understanding of software architecture, scalability, security, and performance optimization.
Preferred Qualifications:
Experience building AI-powered or agent-based applications.
Familiarity with API Gateways, service meshes, and distributed systems.
Experience working in cloud-native and containerized environments.
Strong problem-solving and communication skills.
ClinDCast logo

About ClinDCast

Sourced by ZipRecruiter

ClinDCast is at the forefront of shaping the future of healthcare by partnering with globally recognized healthcare organizations and offering them innovative solutions and expert guidance. Our suite of services is designed to cater to a broad range of needs of healthcare organizations, including healthcare IT innovation, electronic health record (EHR) implementation & optimizations, data conversion, regulatory and quality reporting, enterprise data analytics, FHIR interoperability strategy, payer-to-payer data exchange, and application programming interface (API) strategy. With 15+ Years Of Healthcare IT Industry Experience, ClinDCast Is A Trusted Partner For Payers, Providers, And Lifesciences Organizations, Enabling Them To Deliver Exceptional Product And Solutions For Their Customers.

Industry

Health care and social assistance

Company size

11 - 50 Employees

Headquarters location

Wesley Chapel, FL, US

Social media

Twitter

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