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Python Software Engineer Jobs in Indianapolis, IN

Software Engineer III (AI/ML) Location: Remote - EST preferred Duration: Contract - 12 months Pay ... Proficiency with Python for ML workflows and data processing, including PyTorch or similar ...

The Software Engineer will work together with Software Team Lead to coordinate and oversee design and development of future engineered products (new versions of Exacta, various automation and device ...

The Software Engineer will work together with Software Team Lead to coordinate and oversee design and development of future engineered products (new versions of Exacta, various automation and device ...

Software Engineer Reports To: Lead Software Engineer Department: Product & Engineering FLSA: Exempt About us: 120Water is a mission-driven SaaS company helping government agencies and utilities ...

As a Software Engineer at Liberty Mutual, you'll apply your talents in an agile environment that combines the creative energy of a start-up with the stability and benefits of a Fortune 100 company.

SEP has openings for experienced lead software engineers. We've been helping companies build great ... Professional experience with mainstream development technologies (JavaScript, .NET, Python, iOS ...

SEP has openings for experienced lead software engineers. We've been helping companies build great ... Professional experience with mainstream development technologies (JavaScript, .NET, Python, iOS ...

SEP has openings for experienced lead software engineers. We've been helping companies build great ... Professional experience with mainstream development technologies (JavaScript, .NET, Python, iOS ...

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Python Software Engineer information

See Indianapolis, IN salary details

$20.2K

$122.7K

$177.6K

How much do python software engineer jobs pay per year?

As of Jul 8, 2026, the average yearly pay for python software engineer in Indianapolis, IN is $122,749.00, according to ZipRecruiter salary data. Most workers in this role earn between $96,900.00 and $144,300.00 per year, depending on experience, location, and employer.

Will AI replace Python coders?

Python software engineers develop and maintain code, and while AI tools can automate some coding tasks, they are unlikely to fully replace human programmers soon. AI can assist with code generation and debugging, but complex problem-solving, design, and understanding user needs remain human skills. Continuous learning and adapting to new tools are important for Python developers to stay relevant.

Are Python engineers in demand?

Python engineers are in high demand across various industries such as technology, finance, and data science due to Python's versatility and widespread use in web development, automation, and machine learning. Employers seek professionals with strong programming skills, experience with frameworks like Django or Flask, and knowledge of data analysis tools, making Python engineering a strong career choice with good job prospects.

Is Python a high paying skill?

Python software engineers are generally among the higher-paid programming professionals due to the language's widespread use in data science, web development, and automation. Salaries vary based on experience, location, and industry, but Python skills are considered valuable and can lead to high-paying roles. Mastery of related tools like frameworks and libraries can further increase earning potential.

Can I be a software engineer with Python?

Yes, Python is a popular programming language for software engineers, especially in fields like web development, data analysis, and automation. Proficiency in Python, along with knowledge of related tools and frameworks, is often required for software engineering roles that involve scripting, backend development, or data processing.

What is a Python Software Engineer job?

A Python Software Engineer is a developer who designs, develops, and maintains software applications using the Python programming language. They work on a variety of tasks, including writing clean and efficient code, debugging, optimizing performance, and integrating third-party services or APIs. Python engineers often collaborate with teams to build web applications, data pipelines, machine learning models, or automation scripts, depending on the industry. Their role requires strong problem-solving skills and familiarity with software development best practices.

What does a typical workday look like for a Python Software Engineer?

A typical workday for a Python Software Engineer involves writing and testing code, participating in team meetings to plan and review tasks, and collaborating with colleagues such as front-end developers, quality assurance engineers, and project managers. You may spend time troubleshooting bugs, reviewing pull requests, and improving existing software modules. Many teams use Agile or Scrum methodologies, so your day may include short stand-up meetings and iterative development cycles. Depending on the company, you might also have opportunities to contribute to design discussions or mentor junior developers.

What are the key skills and qualifications needed to thrive in the Python Software Engineer position, and why are they important?

To thrive as a Python Software Engineer, you need strong programming skills in Python, a solid understanding of algorithms and data structures, and a relevant degree in computer science or related fields. Experience with frameworks like Django or Flask, familiarity with version control systems such as Git, and optional certifications like PCEP or PCAP can be valuable assets. Problem-solving skills, teamwork, and effective communication help you navigate complex projects and collaborate efficiently. Mastering both technical and soft skills is crucial for building reliable software solutions and succeeding in dynamic development teams.

What are the most commonly searched types of Python Software Engineer jobs in Indianapolis, IN? The most popular types of Python Software Engineer jobs in Indianapolis, IN are:
What are popular job titles related to Python Software Engineer jobs in Indianapolis, IN? For Python Software Engineer jobs in Indianapolis, IN, the most frequently searched job titles are:
What job categories do people searching Python Software Engineer jobs in Indianapolis, IN look for? The top searched job categories for Python Software Engineer jobs in Indianapolis, IN are:
What cities near Indianapolis, IN are hiring for Python Software Engineer jobs? Cities near Indianapolis, IN with the most Python Software Engineer job openings:
Infographic showing various Python Software Engineer job openings in Indianapolis, IN as of July 2026, with employment types broken down into 82% Full Time, and 18% Contract. Highlights an 78% In-person, 16% Hybrid, and 6% Remote job distribution, with an average salary of $122,749 per year, or $59 per hour.
Senior Software Engineer for Medical Device Startup

Senior Software Engineer for Medical Device Startup

Levisonics Inc

Fishers, IN โ€ข On-site

$115K - $152K/yr

Full-time

Medical, Dental, Vision, PTO

Posted 29 days ago


Job description

About Us:ย 
We are a dynamic and innovative medical device startup developing a point-of-care portable blood coagulation testing device. Our full-time team currently comprises a CEO/Biomedical Engineer, and an Electrical Engineer.ย 

Job Summary:ย 
We are seeking a talented and experienced Senior Software Engineer to join our team and lead the development and optimization of software workflows for our innovative acoustic tweezing technology-based medical devices. The ideal candidate will have a Master's degree in Computer Science, Software Engineering, or a related field, with a minimum of 5 years of experience. This role requires strong coding skills in Python and C/C++, proficiency in developing intuitive and visually engaging graphical user interfaces, and expertise in SQL for effective data management and database design. Experience with version control systems, particularly Git, is essential, along with the ability to understand and generate code from workflow diagrams. As the first and only software engineer on the team, you will play a pivotal role in shaping the software development efforts for our groundbreaking technology. This role is critical to the success of our product and involves working on multiple federal grants and projects.ย 

Startup Environment:ย 
We operate in a fast-paced startup environment where innovation, adaptability, and a proactive mindset are key to success. We are looking for individuals who are passionate about working in a startup setting and thrive in dynamic and challenging situations. We value individuals who are not just seeking a job but are driven by a genuine passion for creating impactful solutions and driving change in the medical device industry. Our team members are expected to work well under pressure, juggle multiple projects, and be flexible in their roles as the needs of the company evolve. If you are excited about the opportunity to make a meaningful impact and are ready to roll up your sleeves and tackle challenges head-on, we encourage you to apply.ย 

Key Responsibilities:ย 

  1. Optimize and Enhance Existing Software:ย 

  • Improve the efficiency of our existing software written in Python.ย 

  • Increase processing speed for short-term operation on laptops.ย 

  • Convert and optimize the software for embedded computing devices inside the medical device long-term.ย 

  1. Software Packaging and Security:ย 

  • Secure the code to prevent reverse engineering.ย 

  • Package the software into executable files for easy installation and deployment.ย 

  1. Connectivity and Data Management:ย 

  • Ensure the software can connect to the internet.ย 

  • Implement connectivity to an online database for long-term data management.ย 

  • Incorporate Data Science, Machine Learning, and AI for handling large amounts of health data.ย 

  1. Health Data Security:ย 

  • Ensure the highest level of security for software and health data management.ย 

  1. New Technique Development:ย 

  • Convert and develop existing crude MATLAB codes and technology algorithms into efficient software for commercial use.ย 

  • Create executable files with efficient large data handling capabilities.ย 

  • Develop complex data processing software and manage large data analysis.ย 

  • Develop a user-friendly interface for healthcare professionals.ย 

  • Implement a remote kill switch for the software.ย 

  • Apply all relevant requirements from existing software.ย 

  1. Parallel Processing and Language Conversion:ย 

  • Implement efficient parallel processing techniques.ย 

  • Convert existing Python code to C/C++ or another suitable low-level efficient language to run software optimally on embedded hardware.ย 

  1. Other Responsibilities:ย 

  • Develop high-quality, efficient, and maintainable code.ย 

  • Design intuitive and visually engaging user interfaces.ย 

  • Proactively take on new responsibilities and suggest innovative ideas for product and company growth.ย 

  • Participate in grant writing and fundraising activities.ย 

  • Engage in FDA-related activities and adhere to quality protocols.ย 

  • Perform other relevant software-related tasks as needed for the company.ย 

Minimum Qualifications:ย 

  • Masterโ€™s degree in Computer Science, Software Engineering, or a related field.ย 

  • Minimum of 5 years of experience in software development.ย 

  • Strong coding skills in Python, C, and C++ (JavaScript is a plus).ย 

  • Proficiency in developing intuitive and visually engaging graphical user interfaces.ย 

  • Proficiency in SQL for effective data management and database design.ย 

  • Experience with version control systems, particularly Git.ย 

  • Ability to understand and generate code from workflow diagrams.ย 

  • Knowledge of integrating multiple devices and establishing centralized control.ย 

  • Familiarity with IDEs, preferably PyCharm.ย 

  • Excellent problem-solving skills and ability to work independently.ย 

  • Strong written and verbal communication skills.ย 

Preferred Qualifications:ย 

  • Experience working in the medical device industry.ย 

  • Familiarity with Agile development methodologies.ย 

  • Knowledge of machine learning techniques and algorithms.ย 

  • Experience with Docker and containerization technologies.ย 

  • Familiarity with cloud platforms such as AWS or Azure.ย 

  • Prior experience working in startups.ย 

  • Experience with embedded systems and medical device software development.ย 

  • Strong knowledge of data security, especially related to health data.ย 

  • Knowledge of parallel processing and algorithm optimization.ย 

  • Innovative mindset with a track record of proactive contributions.ย 

  • Experience in grant writing and regulatory compliance (FDA).ย 

What We Offer:ย 

  • Competitive salaryย 

  • Health, dental, and vision insurance coverageย 

  • Generous paid time offย 

  • Professional development opportunitiesย 

  • Potential to receive stock optionsย 

  • Opportunities for growth within the companyย 

  • Flexible work arrangements, including remote work optionsย 

  • Dynamic and innovative startup environmentย 

  • Opportunity to make a meaningful impact in the medical device industryย 

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