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Python Developer Remote Jobs in San Diego, CA (NOW HIRING)

DivIHN

Sr SW Test Development Engineer - Remote

San Diego, CA · On-site +1

$117K - $152K/yr

San Diego, CA (Remote) Ocasional office visits required only for hardware pickup and meetings in ... Candidates with Python and strong OOP programming experience can also be considered if they are ...

Icwgroup

DevSecOps Engineer II

San Diego, CA · On-site +1

CERTIFICATES, LICENSES, REGISTRATIONS Linux, AWS Cloud Practitioner, AWS DevOps Engineer Associate ... Solid experience with automation tools (Ansible, Puppet, Chef, Python, Powershell). Experience with ...

DataAnnotation

Programmer - AI Trainer

Carlsbad, CA · On-site +1

$50 - $100/hr

Contribute to developing cutting-edge AI systems, while enjoying the flexibility of remote work and ... other engineers -- who are driving real-world impact in AI development. Our platform offers an ...

New

TEAM

Full Stack Developer

San Diego, CA · On-site +1

Job type: Full Time / Hybrid (2 days remote, 3 days in office) Location: 3131 Camino del Rio N, Ste ... Python, and Azure Cloud Services. * Design and implement database queries in MS SQL, Cosmos DB, and ...

Singular Genomics

Software Engineer

San Diego, CA · On-site +1

If remote, travel to the headquarters in San Diego, CA will be required at least quarterly ... Solid Python skills; comfortable working in a large, production codebase with real operational ...

Singular Genomics

Software Engineer

San Diego, CA · On-site +1

If remote, travel to the headquarters in San Diego, CA will be required at least quarterly ... Solid Python skills; comfortable working in a large, production codebase with real operational ...

Dexcom, Inc.

Staff Software Developer

San Diego, CA · On-site +1

You design, develop, and maintain robust, scalable software applications using Python or JavaScript ... Remote Workplace: * Your location will be a home office; you are not required to live within ...

Hired Recruiters

Senior Software Engineer

San Diego, CA · Remote

$130K - $171K/yr

Location: 100% US/Canada remote * In Office Locations: San Francisco, San Diego, Toronto * ~60 ... Node, Python, React, MongoDB, AWS * Visa Support Unknown About the Role * Contribute to the ...

Posted today

VUPICO

Software Engineer

San Diego, CA · On-site +1

$138K - $178K/yr

... such as Java, Python, and C++, to develop software products that meet our clients' needs ... remote work options. Salary: $138,000-$178,000 per year Join Our Team: If you are a talented and ...

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Python Developer Remote information

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How much do python developer remote jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for python developer remote in San Diego, CA is $62.24, according to ZipRecruiter salary data. Most workers in this role earn between $51.30 and $70.67 per hour, depending on experience, location, and employer.

What is a remote Python developer?

Remote Python developer positions design, code, and troubleshoot software and applications using the Python programming language. Instead of working in the office, remote Python developers work from home or another location outside of the office with internet connectivity. Remote Python developers often work on server-side projects related to databases, web servers, and big data manipulation. Your responsibilities include coding specific software functions, testing the format, and debugging issues. Depending on the project, you may start from scratch and build a brand new application, add features to the company's current software, or streamline existing code within the applications used throughout the company. Remote Python developers may work on the staff of an organization or be independent contractors with many different clients.

What does a remote Python developer do?

A remote Python developer designs, builds, and maintains software applications using the Python programming language, working from a location outside of a traditional office environment. Their responsibilities often include writing clean and efficient code, debugging and troubleshooting issues, collaborating with team members through online tools, and integrating third-party services or APIs. Remote Python developers may work on web applications, data analysis, automation scripts, or back-end systems, depending on the employer's needs. They must also manage their time effectively and communicate clearly to succeed in a distributed team setting.

What are some common challenges faced by remote Python developers, and how can they be addressed?

Remote Python Developers often face challenges related to communication, collaboration, and staying aligned with team goals due to physical distance. To address these issues, it's important to establish clear communication channels, actively participate in daily stand-ups or sync meetings, and utilize project management tools. Regular code reviews and pair programming sessions can also help maintain code quality and foster teamwork. Additionally, setting up a dedicated and distraction-free workspace at home can significantly boost productivity.

What is the difference between Python Developer Remote vs Data Analyst Remote?

AspectPython Developer RemoteData Analyst Remote
Required SkillsPython, programming, software developmentData analysis, SQL, Excel, visualization
Work EnvironmentRemote, tech companies, software firmsRemote, finance, marketing, consulting
Common CertificationsPython certifications, coding bootcampsData analysis certifications, Excel, SQL

Python Developer Remote and Data Analyst Remote roles often share a remote work environment and require technical skills. However, Python Developers focus on coding and software development, while Data Analysts specialize in analyzing data and generating insights. Both roles are in high demand across various industries and often require similar certifications, making them popular choices for remote tech careers.

More about Python Developer Remote jobs

What are the most commonly searched types of Python Developer jobs in San Diego, CA?

The most popular types of Python Developer jobs in San Diego, CA are:

What are popular job titles related to Python Developer Remote jobs in San Diego, CA?

For Python Developer Remote jobs in San Diego, CA, the most frequently searched job titles are:

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The top searched job categories for Python Developer Remote jobs in San Diego, CA are:

What cities near San Diego, CA are hiring for Python Developer Remote jobs?

Cities near San Diego, CA with the most Python Developer Remote job openings:

Python Developer Remote jobs near you
Infographic showing various Python Developer Remote job openings in San Diego, CA as of August 2026, with employment types broken down into 95% Full Time, and 5% Contract. Highlights an 100% Remote job distribution, with an average salary of $129,457 per year, or $62.2 per hour.

Senior Generative AI Engineer (Google Gemini & Vertex AI) - Remote

DivIHN

San Diego, CA • On-site, Remote

$110K - $152K/yr

Contractor

Posted 15 days ago

Job description

For further inquiries about this opportunity, please contact one of our Talent Specialists, Justeen at (224)-394-4903
Title: Senior Generative AI Engineer (Google Gemini & Vertex AI) - Remote
Duration: 6 Months with possible for extension
Location: Remote
Candidates must be available to work West Coast (PST) hours.
Only W2 candidates are eligible for this position. Third-party or C2C candidates will not be considered.
Day to Day Responsibilities
  • RAG & Prompt Engineering: Craft and refine effective prompts for RAG, grounding, and context tuning to achieve optimal AI performance in product development.
  • High-Performance API Engineering: Develop asynchronous microservices (FastAPI) using Server-Sent Events (SSE) or WebSockets to stream real-time LLM responses to front-end UIs without backend timeouts.
  • Vector Database Infrastructure: Design, develop, and implement robust Vector Databases using LLMs and modern retrieval technologies to capture information from diverse engineering sources (PDFs, design docs, regulatory guidelines).
  • Data Extraction & Structuring Pipelines: Build and optimize pipelines to extract and structure multi-modal data (tables, text, images) from unstructured documents for LLM training, grounding, and runtime query execution.
  • LLM Fine-Tuning & Training: Fine-tune and train generative AI models using client's engineering data and domain knowledge to create high-accuracy, domain-specific models.
  • GenAI Application & Tool Development: Design and implement scalable backend APIs (FastAPI/REST) and UI integration interfaces so internal engineers can query knowledge bases and analyze data.
  • Automated Requirements Generation: Develop backend functionalities to automatically generate technical requirements from design documents, user stories, and system specification files.
  • Documentation & Knowledge Transfer: Thoroughly document architecture, code, REST endpoints, and model training procedures to enable seamless knowledge transfer to client's internal teams.
  • Cross-Functional Collaboration: Partner closely with Subject Matter Experts (SMEs), System Engineers, and V&V Test teams to optimize AI-powered workflows.
  • AI Guardrails, MLOps & Cost Governance: Implement hallucination checks, PII masking, and guardrails (e.g., NeMo Guardrails) for medical device context. Track token usage, latency, and costs using LangSmith or Vertex AI monitoring.
  • Collaborate closely with engineers and cross-functional teams to design and develop AI solutions.
  • Develop and integrate Generative AI applications and APIs.
  • Work with large datasets, document processing, and data pipelines.
  • Participate in problem-solving, solution design, and technical discussions.
  • Communicate effectively with team members and stakeholders.

Must-Have Qualifications :
  • Relevant Experience & STEM Foundation: 4+ years of professional software/ML engineering experience, with a dedicated AI/ML focus in the last 1-2 years.
  • Google Gemini / Vertex AI (Non-negotiable): Hands-on experience with the Gemini model family and Vertex AI, including deployment, grounding, and integration into production AI services. Hands-on experience with containerization (Docker) and deploying services via Cloud Run or GKE (Kubernetes).
  • Languages & AI Libraries: Proficiency in Python and modern ML/AI frameworks (PyTorch, LangChain, LangSmith) for building autonomous LLM agents, tools, and RAG pipelines.
  • Agent Building & Tool Calling: Proven experience building AI/LLM agents and tool-calling systems in Python against unstructured, multi-source data.
  • Context Engineering & RAG: Expertise in RAG pipelines, prompt engineering, context tuning, grounding, and Vector Databases (e.g., Milvus, Postgres/Pgvector). Clear understanding of advanced RAG architecture including Hybrid Search (Vector + Keyword), Re-ranking models, and semantic caching.
  • Unstructured Data Handling (Non-negotiable): Demonstrated ability to ingest, clean, extract, and structure text, tables, and images from unstructured documents (PDFs, design docs, regulatory files) for LLM training and usage.

Role Information
  • Generative AI Engineer role.
  • Experience in API development.
  • Hands-on experience with Google Gemini and Vertex AI.
  • Knowledge of Agentic AI frameworks and architectures.
  • Strong Python development skills, including experience with LangChain and related AI frameworks.
  • Open to candidates from any industry domain.

Required Skills :
  1. Full Stack Engineering - Building applications for AI-powered services (Backend APIs + Front-End Integration).
  2. Generative AI & LLM Platforms - 2+ years building RAG pipelines & LLM apps using Python, LangChain, and LangSmith.
  3. Agent Building & Unstructured Data - Building AI agents/tool-calling systems in Python and handling unstructured, multi-source data extraction (PDFs, docs).
  4. Strong hands-on experience in Artificial Intelligence and Generative AI
  5. Python programming expertise.
  6. Experience with LangChain and Agentic AI frameworks.
  7. Understanding data handling to pull data from PDFs, design docs, regulatory files

Preferred Skills :
  1. Direct experience architecting and serving custom REST APIs.
  2. Experience in regulated / compliance-sensitive domains (e.g., healthcare / medical device guidelines like FDA, ISO 13485).
  3. Experience integrating multiple LLM APIs beyond a single provider (OpenAI, Bedrock, Claude, or similar).

Additional Preferred Skills
  • Direct experience designing and deploying high-throughput REST APIs (e.g., FastAPI/Flask).
  • Familiarity with medical device development regulations and compliance (e.g., FDA guidelines, ISO 13485).
  • Experience integrating multiple LLM APIs beyond a single vendor (e.g., OpenAI, AWS Bedrock, Anthropic Claude).
  • Front-end development/integration experience for UI design (e.g., Streamlit, Gradio, React/Next.js integration).

Education Requirements:
  • Minimum Bachelors in Software/Computer/IT/Systems/Biomedical Engineering + 3 years

Required Testing:
  • Technical evaluation of Python proficiency, RAG architecture concepts, and API/Agent design.

Software Skills Required:
  • Languages: Python (AsyncIO, OOP), SQL.
  • AI & Agent Frameworks: PyTorch, LangChain, LangSmith, Vertex AI SDK.
  • API & Web Frameworks: FastAPI, Flask, REST APIs, Server-Sent Events (SSE).
  • Databases & Search: Milvus, Pgvector, Qdrant, Redis (caching).
  • Front-End Integration: Streamlit, Gradio, basic React/Next.js.
  • Testing & Guardrails: pytest, JUnit, LangSmith evaluation, NeMo Guardrails.
  • DevOps & Cloud: Docker, GCP (Vertex AI, Cloud Run, GKE), Git.

Required Certifications:
  • Professional certifications specific to AI/ML (e.g., Certified AI Professional / CAIP, Google Cloud ML Engineer) considered a plus.

Interview
  • Number of Interviews: 1,
  • Web Conference (Zoom/ TEAMs)
  • Live problem-solving and technical exercise during the interview.

Apply