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Python Ai Developer Jobs in Cambridge, MA (NOW HIRING)

RxSense

Principal Software Engineer, AI-Native

Boston, MA · On-site

$210K - $275K/yr

NET, Python, and the occasional TypeScript front end), and you will lead development of our AI ... Our engineers build with modern agentic tooling standardized on Anthropic's Claude, so you will ...

StradIT

Python Developer

Boston, MA · On-site

$54.50 - $75.25/hr

o Design, develop, test, and maintain scalable Python applications and services. o Build and ... AI/ML initiatives by developing data processing components and integrating machine learning ...

YO AI Labs

GIS/Geospatial Expert

Boston, MA · Remote

$80 - $100/hr

Experience evaluating AI-generated code or multi-step agent workflows rather than using AI agents solely for conversational assistance. * Strong Python programming experience and familiarity with ...

YO AI Labs

GIS/Geospatial Expert

Boston, MA · Remote

$80 - $100/hr

Experience evaluating AI-generated code or multi-step agent workflows rather than using AI agents solely for conversational assistance. * Strong Python programming experience and familiarity with ...

hOS

Python Developer

Boston, MA · On-site

$54.50 - $75.25/hr

The company is operating in stealth-mode developing scalable technologies and AI-driven products ... years of Python experience, 5+ years of software engineering experience * Proficiency in unit ...

Varsity Tutors

Python Tutor

Lynn, MA · Remote

$40/hr

Our AI-powered Tutor Copilot enhances your sessions with real-time instructional support, lesson ... Ability to explain Pythonic programming conventions, decorators, and generators while preparing ...

Varsity Tutors

Python Tutor

Newton, MA · Remote

$40/hr

Our AI-powered Tutor Copilot enhances your sessions with real-time instructional support, lesson ... Ability to explain Pythonic programming conventions, decorators, and generators while preparing ...

Varsity Tutors

Python Tutor

Quincy, MA · Remote

$40/hr

Our AI-powered Tutor Copilot enhances your sessions with real-time instructional support, lesson ... Ability to explain Pythonic programming conventions, decorators, and generators while preparing ...

Varsity Tutors

Python Tutor

Lowell, MA · Remote

$40/hr

Our AI-powered Tutor Copilot enhances your sessions with real-time instructional support, lesson ... Ability to explain Pythonic programming conventions, decorators, and generators while preparing ...

Varsity Tutors

Python Tutor

Cambridge, MA · Remote

$40/hr

Our AI-powered Tutor Copilot enhances your sessions with real-time instructional support, lesson ... Ability to explain Pythonic programming conventions, decorators, and generators while preparing ...

Varsity Tutors

Python Tutor

Waltham, MA · Remote

$40/hr

Our AI-powered Tutor Copilot enhances your sessions with real-time instructional support, lesson ... Ability to explain Pythonic programming conventions, decorators, and generators while preparing ...

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Python Ai Developer information

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How much do python ai developer jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for python ai developer in Cambridge, MA is $64.07, according to ZipRecruiter salary data. Most workers in this role earn between $52.79 and $72.79 per hour, depending on experience, location, and employer.

What does a Python AI Developer do?

A Python AI Developer designs, builds, and implements artificial intelligence applications using the Python programming language. Their work often involves developing machine learning models, processing large datasets, and integrating AI solutions into software products. They collaborate with data scientists, engineers, and stakeholders to solve complex problems and optimize AI algorithms for real-world use. Python AI Developers stay updated on the latest AI techniques and ensure their solutions are efficient, scalable, and maintainable.

What are the key skills and qualifications needed to thrive as a Python AI Developer?

To thrive as a Python AI Developer, you need strong programming skills in Python, a solid understanding of machine learning concepts, and a background in mathematics or computer science. Familiarity with frameworks and libraries such as TensorFlow, PyTorch, scikit-learn, and experience with data processing tools are typically required. Analytical thinking, problem-solving abilities, and effective collaboration are crucial soft skills for this role. These competencies enable developers to design, implement, and optimize AI solutions that address complex real-world challenges efficiently.

How does a Python AI Developer typically collaborate with data scientists and other team members during an AI project?

Python AI Developers often work closely with data scientists, machine learning engineers, and product managers throughout the lifecycle of an AI project. They are responsible for implementing algorithms and models designed by data scientists, optimizing code for efficiency, and integrating AI solutions into production environments. Regular communication and code reviews ensure alignment on objectives and technical standards, while agile practices like daily stand-ups facilitate cross-functional collaboration. Being open to feedback and adaptable to changing project requirements is key to success in this role.

How to become a Python AI developer?

To become a Python AI developer, you should gain proficiency in Python programming, understand machine learning and deep learning concepts, and work with frameworks like TensorFlow or PyTorch. Building a strong foundation in mathematics, such as linear algebra and statistics, and gaining experience through projects or certifications can enhance your skills. Familiarity with data handling, algorithms, and software development practices is also essential.

What is the salary of a Python AI developer?

The salary of a Python AI developer typically ranges from $80,000 to $150,000 annually, depending on experience, location, and industry. Skilled developers with expertise in machine learning frameworks and data analysis tools tend to earn higher salaries.

What job categories do people searching Python Ai Developer jobs in Cambridge, MA look for?

The top searched job categories for Python Ai Developer jobs in Cambridge, MA are:

What cities near Cambridge, MA are hiring for Python Ai Developer jobs?

Cities near Cambridge, MA with the most Python Ai Developer job openings:

Python Ai Developer jobs near you
Infographic showing various Python Ai Developer job openings in Cambridge, MA as of August 2026, with employment types broken down into 71% Full Time, 17% Part Time, and 12% Contract. Highlights an 63% Physical, 4% Hybrid, and 33% Remote job distribution, with an average salary of $133,269 per year, or $64.1 per hour.

Principal Software Engineer, AI-Native

Boston, MA • On-site

RxSense
Health Care and Social Assistance • 51 - 200 employees
Learn more about RxSenseexternal

$210K - $275K/yr

Full-time

Re-posted 4 days ago

Job description

We are a healthcare technology company that provides platforms and solutions to improve the management and access of cost-effective pharmacy benefits. Our technology helps enterprise and partnership clients simplify their businesses and helps consumers save on prescriptions.

As a leader in SaaS technology for healthcare, we offer innovative solutions with integrated intelligence on a single enterprise platform that connects the pharmacy ecosystem.  With our expertise and modern, modular platform, our partners use real-time data to transform their business performance and optimize their innovative models in the marketplace.

Position summary

RxSense is becoming an AI native company, and AI is the primary lever behind our next phase of growth.

This is a deeply technical, architect level role. You will sit on the AI Engineering team and set the technical standard the broader engineering organization looks to, leading through example and craft rather than mandate. You will architect and build systems across our stack (C#/.NET, Python, and the occasional TypeScript front end), and you will lead development of our AI evaluation infrastructure, both offline (test suites, golden datasets, and regression harnesses wired into CI/CD) and online (continuous monitoring of live model and system behavior).

Working in this domain is compelling because two things must hold true at once. Our systems need to be correct, since we operate in a regulated, high stakes domain where evaluation and trustworthy behavior matter as much as the features themselves. Our systems also need to be fast, since they run at high volume and low latency, where performance compounds at scale. Much of this role is about helping projects move quickly while staying confident in the products we ship.

You will do this work in an AI forward environment. Our engineers build with modern agentic tooling standardized on Anthropic's Claude, so you will have first class tools for the work ahead.

Responsibilities

  • Architect and build production systems across a multi language stack: C#/.NET services, Python AI and data pipelines, and occasional TypeScript
  • Set the example for an AI forward, high technical standard across the broader engineering organization, leading through craft rather than organization wide authority
  • Design and drive adoption of offline evaluation frameworks (test suites, golden datasets, regression harnesses wired into CI/CD) for LLM based and other non deterministic components
  • Build online evaluation and monitoring that continuously assesses live model and system behavior in production, including drift and regression detection
  • Partner with engineering leadership to surface systemic risks in AI features, such as reliability, correctness, and drift, and drive the fixes
  • Lead architecture reviews for major initiatives and mentor senior and staff engineers on system design, evaluation methodology, and AI forward practices
  • Prototype and ship new AI capabilities

What success looks like

Day to day, you move between writing production code, shaping architecture across teams, and building the evaluation tooling that gives RxSense confidence in its AI systems before and after they ship. 

Qualifications

  • 8+ years of professional software engineering experience, with demonstrated Staff, Principal, or Architect-level scope — e.g., owning system architecture end-to-end, driving technical strategy across multiple teams, or being accountable for critical production systems. We evaluate candidates on the scope and impact of their work rather than years of experience alone; strong candidates with less tenure but clear evidence of this level of ownership are encouraged to apply. 
  • Depth across backend and AI/ML systems, working in some combination of C#/.NET, Python, and TypeScript.
  • Experience with LLM observability, prompt and response evaluation, or agentic system testing
  • A track record of setting technical standards that other engineers and teams adopt.
  • Strong communication skills, with the ability to align engineers and leadership around a shared technical direction.
  • Comfort working in an AI forward engineering environment, for example with agentic coding tools such as Claude Code.
  • Bachelor's degree in Computer Science, Engineering, or a related field preferred. Equivalent practical experience will be considered in lieu of a formal degree. 

Preferred

  • Experience in pharmacy benefits, healthcare, fintech, or another regulated, high stakes domain.
  • Familiarity with distributed systems tooling such as Kafka, gRPC, Grafana, and Dragonfly / Redis.
  • A good eye for clean, usable interfaces for the occasional front end work.

Salary Range- $210,000- $275,000

RxSense believes that a diverse workforce is a more talented and productive workforce. As such, we are an Equal Opportunity and Affirmative Action employer. Our recruitment process is free from discriminatory hiring practices and all qualified applicants are considered for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin.  Neither will qualified applicants be discriminated against on the basis of disability or protected veteran status.  We believe in the strength of the collaboration, creativity and sense of community a diverse workforce brings.