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Overview

The Director, Medical Publications - TTR Franchise will lead the strategic development and execution of the global medical publication plan for Alnylam's transthyretin amyloidosis (TTR) franchise. As a key member of the Medical Affairs organization, this individual will play a central role in driving the timely, accurate, and compliant dissemination of clinical and scientific data through peer-reviewed publications and presentations at global congresses. The Director will partner closely with cross-functional colleagues, including Medical Directors, Clinical Development, Biostatistics, Scientific Communications, Legal, and Commercial teams, to ensure publication activities are aligned with the broader medical and corporate strategy.

This role will also lead publication governance, collaborate with key opinion leaders (KOLs) and external authors, and contribute to Alnylam's scientific leadership in cardiology. The position requires a high level of scientific expertise, strategic acumen, and operational excellence.

Key Responsibilities

• Lead the development, execution, governance, and continuous optimization of the global publication strategy and plan for the TTR Franchise, ensuring alignment with overarching medical, evidence generation, and corporate objectives.
• Serve as the publication lead for the TTR Franchise and the primary strategic partner to Medical Directors, Clinical Development, Biostatistics, Scientific Communications, Legal, Regulatory, and Commercial stakeholders.
• Chair the cross-functional TTR Publication Working Group and oversee publication governance processes, ensuring high-quality, compliant, and strategically aligned publication planning and execution.
• Lead the full lifecycle of scientific dissemination activities, including abstracts, posters, oral presentations, manuscripts, plain language summaries, encore presentations, and other publication deliverables.
• Lead and continuously enhance publication operations, including management of publication processes, timelines, agency partners, vendors, publication systems, cross-functional collaboration, and performance metrics to ensure efficient and compliant execution.
• Collaborate with external experts, authors, publication steering committee members, and medical writing partners to ensure timely, accurate, and GPP-compliant delivery of scientific communications.
• Lead continuous improvement and innovation initiatives across publication planning and execution, including evaluation and implementation of emerging technologies, artificial intelligence (AI), automation tools, and new ways of working to enhance efficiency, quality, compliance, and scientific impact.
• Monitor external trends and evolving best practices in scientific publishing, publication planning, and AI-enabled content development, translating insights into actionable improvements for the franchise.
• Stay informed of current ATTR amyloidosis literature and provide strategic insights regarding the scientific landscape to inform publication planning and evidence dissemination priorities.
• Represent Alnylam at scientific congresses, publication steering committees, advisory boards, outreach meetings, and interactions with key external experts and thought leaders. Some travel to U.S. and international congresses or for publications activities required.
• Lead and mentor publication team members, fostering a culture of scientific excellence, operational rigor, collaboration, and integrity.
• Demonstrate clear alignment with Alnylam core values in all internal and external interactions.

Qualifications

• PhD preferred; PharmD or MD considered, with 7+ years of relevant pharmaceutical, biotech, medical communications, or medical education experience.
  • CMPP certification preferred.
• Experience in medical affairs, scientific communications, and publications required.
• Experience interacting with scientific experts, external authors, and senior stakeholders required.
• Demonstrated people leadership experience, including direct management and/or matrix leadership required.
• Experience leading publication strategy, planning, governance, and execution for complex global programs required.
• Strong knowledge of GPP, ICMJE authorship criteria, and publication best practices required.
• Experience managing publication vendors, agencies, and external authors required.
• Strong organizational, project management, and operational leadership skills required.
• Demonstrated ability to influence and collaborate effectively in a matrixed environment required.
• Excellent written and verbal communication skills required.
• Experience leading publication working groups and publication steering committees preferred.
• Experience in rare disease, cardiology, or RNA-based therapeutics preferred.
• Experience evaluating or implementing AI-enabled tools, automation solutions, or innovative publication workflows preferred.

#LI-JB1 #LI-Hybrid

U.S. Pay Range

$202,000.00 - $273,400.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.