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Protocol Development Jobs in New York (NOW HIRING)

Aurevia PM

Be Seen First

Medical Director Physician for Telehealth HRT and Weight Loss clinic

New York, NY · Remote

$3.0K - $5.0K/mo

Expertise in clinical protocol development * Demonstrated leadership abilities Pay: Starting rate of $3000-$5000 monthly depending on qualifications with possibility to increase with further growth ...

Staffingine LLC

Sr. Principal Statistics

Paramus, NJ · On-site

The Senior Manager in Statistics responsible for perform statistical activities in clinical trials from protocol development to final study report and statistical activities in drug in-licensing ...

Pathos

Director, Clinical Science

New York, NY · On-site

$200K - $240K/yr

You own protocol development, data review, clinical document authorship, and site-level scientific support from study startup through closeout. You will work closely with Clinical Operations ...

Hired by Matrix

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C&Q Engineer

Raritan, NJ · On-site

$70/hr

Role will focus on protocol development, field execution, data collection and reporting * Documentation Preparation: * * Develop CQV documentation in KNEAT: * URS, SIA, DQ * FAT/SAT protocols

RWJBarnabas Health

Clinical Supervisor RN

Somerville, NJ · On-site

$83K - $117K/yr

While managing staff coordination, competency training, and clinical protocol development, this role maintains a primary focus on strengthening team performance and patient care. Qualifications:

RWJBarnabas Health

Clinical Supervisor RN

Somerville, NJ · On-site

$83K - $117K/yr

While managing staff coordination, competency training, and clinical protocol development, this role maintains a primary focus on strengthening team performance and patient care. Qualifications:

RWJBarnabas Health

Clinical Supervisor RN

Somerville, NJ · On-site

$83K - $117K/yr

While managing staff coordination, competency training, and clinical protocol development, this role maintains a primary focus on strengthening team performance and patient care. Qualifications:

NYULMC

Senior Research Coordinator

New York, NY · On-site

Oversees the financial and protocol development for the assigned studies. Assists with managing the recruitment process (develops advertising strategy, contacts media outlets and negotiate rates and ...

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All JobsProtocol Development JobsProtocol Development Jobs in New York

Protocol Development information

See New York salary details

$31.7K

$58.4K

$88.6K

How much do protocol development jobs pay per year?

As of Jun 27, 2026, the average yearly pay for protocol development in New York is $58,441.00, according to ZipRecruiter salary data. Most workers in this role earn between $46,500.00 and $65,600.00 per year, depending on experience, location, and employer.

What is the difference between Protocol Development vs Clinical Research Associate?

AspectProtocol DevelopmentClinical Research Associate
Primary RoleDesigns and develops clinical trial protocolsMonitors clinical trials to ensure compliance and data integrity
Required SkillsKnowledge of clinical trial design, regulatory guidelines, and writing skillsMonitoring skills, regulatory knowledge, and communication skills
Work EnvironmentTypically in planning, development, and regulatory teamsOn-site or remote monitoring at clinical trial sites
CertificationsOften requires knowledge of GCP, regulatory affairsGCP certification often preferred

While Protocol Development focuses on creating and designing clinical trial protocols, Clinical Research Associates are responsible for monitoring and ensuring trial compliance at sites. Both roles are essential in clinical research but differ in their core responsibilities and work environments.

What does protocol mean?

In protocol development, a protocol is a detailed set of procedures and guidelines that define how data is collected, transmitted, and managed in a research or clinical setting. It ensures consistency, safety, and compliance across studies or projects, often requiring careful documentation and review by regulatory bodies.

What is a protocol in healthcare?

In healthcare, a protocol is a detailed plan or set of guidelines that healthcare professionals follow to ensure consistent and effective patient care. Protocols are used to standardize procedures, improve safety, and guide clinical decision-making, often based on evidence-based practices and requiring regular review and updates.

What are the 4 types of protocols?

In protocol development, the four main types are communication protocols, which define data exchange rules; security protocols, ensuring data protection; operational protocols, outlining procedures and workflows; and compliance protocols, ensuring adherence to regulations. Developing these protocols requires understanding of technical standards, industry requirements, and often involves collaboration with stakeholders.

What are the key skills and qualifications needed to thrive in Protocol Development, and why are they important?

To thrive in Protocol Development, you need a solid background in clinical research, regulatory requirements, and scientific writing, often supported by a degree in life sciences or a related field. Familiarity with tools such as clinical trial management systems (CTMS), electronic data capture (EDC), and knowledge of ICH-GCP guidelines is typically required. Strong attention to detail, project management, and effective communication skills help professionals excel in this role. These competencies ensure the creation of clear, compliant, and scientifically sound protocols that are essential for successful clinical trials.

What is protocol and example?

In protocol development, a protocol is a detailed set of procedures and standards that guide how data is collected, processed, and communicated in research or clinical trials. An example is the Clinical Data Management Protocol, which outlines data collection methods, quality checks, and compliance requirements to ensure consistency and accuracy. Developing protocols requires attention to detail, regulatory knowledge, and collaboration with stakeholders.

What is protocol development?

Protocol development refers to the process of designing and creating detailed plans, often called protocols, which outline the methodology and procedures for conducting research or clinical trials. This includes specifying objectives, study design, data collection methods, and regulatory requirements to ensure the study is scientifically valid and ethically sound. Protocol developers work closely with researchers, regulatory bodies, and stakeholders to ensure all aspects of the protocol meet industry standards and compliance guidelines.

What are the main challenges someone might face when starting in a Protocol Development role?

One of the main challenges in Protocol Development is quickly understanding complex technical standards and aligning them with organizational goals. New team members often need to collaborate closely with cross-functional teams, such as engineering, legal, and product management, to ensure protocols are both technically sound and compliant with industry regulations. Adapting to rapidly evolving technologies and maintaining clear documentation can also be demanding, but strong communication and a willingness to learn can help overcome these hurdles.
What are popular job titles related to Protocol Development jobs in New York? For Protocol Development jobs in New York, the most frequently searched job titles are:
What job categories do people searching Protocol Development jobs in New York look for? The top searched job categories for Protocol Development jobs in New York are:
Protocol Development jobs near you

Protocol Engineer

PulseRise Technologies

New York, NY

Full-time

Posted 21 days ago

Job description

Dear applicants, please keep in mind that applications without provided salary expectations and active LN profile will not be considered. Hope for your understanding.

ONSITE ROLE IN NY 

We are looking for a senior-level Protocol Engineer to join a core blockchain team building next-generation Web3 payments infrastructure. This role is focused on designing and implementing secure, efficient smart contracts and protocol-level components that power cross-chain value transfer at scale. You will operate at the intersection of smart contract development, DeFi mechanics, and blockchain architecture, contributing directly to systems that enable millions of onchain transactions. The position requires a strong crypto-native mindset, deep Solidity expertise, and the ability to reason about protocol design, security, and cross-chain interactions. You will collaborate closely with backend engineers and product teams to architect payment and settlement infrastructure. This is a high-impact opportunity within a growing blockchain team shaping core Web3 primitives.

Details
Location: Midtown NYC; visa sponsorship available
Work Model: Onsite (NYC)
Employment Type: Full-time
Seniority Level: Senior (L1-L4)
Industry: Blockchain / Web3 Payments
Start Date: ASAP

Key Responsibilities
Design, develop, and deploy production-grade smart contracts across major blockchain platforms
Architect secure protocol components for onchain payments and settlement systems
Write highly efficient, well-tested Solidity code
Collaborate with backend and product teams on cross-chain payment flows
Research and evaluate new blockchain networks and interoperability approaches
Contribute to cross-chain communication and bridging strategies
Perform security reviews and proactively mitigate smart contract vulnerabilities
Support incident response and debugging of onchain issues

Requirements
Proven experience building and deploying production smart contracts (Ethereum / L2s)
Strong expertise in Solidity (required)
Deep understanding of DeFi protocols, token standards, and onchain mechanics
Solid knowledge of cross-chain communication patterns
Strong security mindset and awareness of common smart contract vulnerabilities
Ability to reason about protocol architecture and distributed system design
Strong written and verbal communication skills

Nice to Have
Experience with Rust or Move
Production experience across multiple blockchain ecosystems
Familiarity with cross-chain bridges
Experience with formal verification or advanced security tooling
Deep understanding of blockchain architecture and consensus models

Interview Process
Recruiter screening (technical depth, location, compensation alignment)
Technical deep dive with protocol lead / Solidity engineer
Smart contract design and security assessment (live and/or take-home)
Onsite in NYC including technical and cultural interviews
Employment Type: FULL_TIME

Apply