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Protein Expression Jobs in Washington (NOW HIRING)

Axle

Scientist

Rockville, MD

Perform protein assays by Western Blotting to detect protein expression and protein associations in T cells from mice -- 1 * Perform transfection experiments with plasmids and retroviruses into cell ...

New

Axle

Scientist

Rockville, MD · On-site

Perform protein assays by Western Blotting to detect protein expression and protein associations in T cells from mice - 1 * Perform transfection experiments with plasmids and retroviruses into cell ...

New

Axle

Scientist

Rockville, MD · On-site

Perform protein assays by Western Blotting to detect protein expression and protein associations in T cells from mice - 1 * Perform transfection experiments with plasmids and retroviruses into cell ...

New

Guidehouse

Molecular Biologist

Bethesda, MD · On-site

$74K - $124K/yr

Design and optimize recombinant protein expression systems for multiple host platforms. * Perform protein purification and characterization using biochemical and biophysical assays. * Conduct protein ...

Bestzyme

Sr./ Sales Manager, Sweet Protein

Washington, DC · Remote

$100K - $130K/yr

Sales Manager (Sweet Protein) Location: United States - Remote The estimated salary range is $100 ... or expression, age, disability, national origin, marital or domestic/civil partnership status ...

Varsity Tutors

AP Biology Tutor

Rockville, MD · Remote

$18 - $40/hr

Ability to explain natural selection mechanisms, gene expression regulation, cellular respiration ... Skilled at breaking down complex biological processes including DNA replication, protein synthesis ...

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Protein Expression information

What is protein expression?

Protein expression refers to the process by which proteins are synthesized, modified, and regulated in living organisms. In biotechnology and research, protein expression often means the artificial production of specific proteins in host cells, such as bacteria, yeast, or mammalian cells, using recombinant DNA technology. This process is crucial for studying protein function, developing pharmaceuticals, and producing enzymes or other protein-based products. The choice of expression system depends on factors like the protein's complexity and the need for post-translational modifications.

What are the key skills and qualifications needed to thrive as a protein expression scientist, and why are they important?

To thrive as a Protein Expression Scientist, you need a strong background in molecular biology, biochemistry, and cell culture, often supported by a relevant degree (such as in biology, biochemistry, or biotechnology). Familiarity with expression systems (E. coli, yeast, insect, or mammalian cells), chromatography, and analytical tools like SDS-PAGE and Western blot is essential, and experience with laboratory information management systems (LIMS) or certifications in laboratory safety can be advantageous. Strong problem-solving abilities, attention to detail, and effective communication skills are valuable soft skills in this field. These competencies ensure accurate protein production, efficient troubleshooting, and clear collaboration, which are crucial for successful research and development in biotechnology and pharmaceutical settings.

What are some common challenges faced in a protein expression role, and how can they be addressed?

Professionals in Protein Expression often encounter challenges such as optimizing expression levels, ensuring protein solubility, and maintaining protein functionality. Troubleshooting requires a strong understanding of expression systems (bacterial, yeast, insect, or mammalian), vector design, and purification methods. Collaboration with molecular biologists and biochemists is essential to troubleshoot issues and adapt protocols, while ongoing learning about new expression technologies can help address complex problems and enhance productivity.

What is the difference between Protein Expression vs Protein Purification?

AspectProtein ExpressionProtein Purification
Primary FocusProducing proteins within cells or systemsIsolating and cleaning proteins from mixtures
Work EnvironmentLaboratories involving genetic engineering and cell cultureLaboratories focused on protein isolation and analysis
Required SkillsMolecular biology, cloning, cell cultureChromatography, protein analysis, assay techniques
Industry UsageBiotech, pharmaceuticals, researchBiotech, pharmaceuticals, research

Protein Expression involves creating proteins within cells using genetic techniques, while Protein Purification focuses on isolating and refining those proteins for study or application. Both roles are essential in biotech and research settings, often overlapping but distinct in their primary objectives.

What are popular job titles related to Protein Expression jobs in Washington?

For Protein Expression jobs in Washington, the most frequently searched job titles are:

What job categories do people searching Protein Expression jobs in Washington look for?

The top searched job categories for Protein Expression jobs in Washington are:

What cities in Washington are hiring for Protein Expression jobs?

Cities in Washington with the most Protein Expression job openings:

Protein Expression jobs near you
Infographic showing various Protein Expression job openings in Washington as of August 2026, with employment types broken down into 1% As Needed, 70% Full Time, 22% Part Time, 2% Temporary, and 5% Contract. Highlights an 89% Physical, 2% Hybrid, and 9% Remote job distribution.

Senior Scientist, Bioproduction and Bioprocessing

Join Our Team

Rockville, MD • On-site

$93K - $127K/yr

Full-time

Medical, Dental, Vision, Life

Posted 21 days ago

Job description

Description:

The Senior Scientist, Bioproduction & Bioprocessing is responsible for leading the development, optimization, and execution of mammalian cell-based protein production workflows to support organizational research, development, and manufacturing needs. This role provides subject-matter expertise in cell line development, transient expression, and upstream bioprocessing, and ensures high-quality delivery of materials through collaboration with cross-functional teams. The Senior Scientist contributes to scientific innovation, process improvement, and customer support activities.

  • Lead and execute workflows for stable pool and stable cell line generation, including transfection, clone screening, productivity assessment, and documentation.
  • Perform stable pool and transient experiments using CHOZN, CHOK1-sv, CHOK, HEK293, and other protein production-relevant cell lines.
  • Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins.
  • Conduct upstream protein expression studies, including small-scale evaluations and preparation for scale-up.
  • Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations.
  • Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders.
  • Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials.
  • Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists.
  • Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement.
  • Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability.
  • Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows.
  • Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion.
  • Provide technical insight to support long-term bioproduction strategy and organizational growth.
  • Maintain accurate, complete, and compliant laboratory records.
  • Ensure adherence to organizational, regulatory, and safety standards.
Requirements:
  • PhD in biological sciences or related field with 10+ years of relevant industry experience (or Master’s degree with 13+ years of experience) in bioproduction, bioprocessing, or cell line development
  • Demonstrated expertise in stable cell line development and clone selection.
  • Extensive hands-on experience with transient expression of antibodies or recombinant proteins.
  • Strong foundation in mammalian cell culture and upstream protein expression.
  • Experience with high-throughput screening, automation, or advanced analytical tools.
  • Background in cell engineering, vector design, media/feed optimization, or bioprocess development.
  • Prior experience in structured, milestone-driven industry or core laboratory environments.
  • Good communication skills and ability to work collaboratively with internal team members and customers
  • Ability to travel up to 20%


MaxCyte offers a base salary, annual bonus, and equity. MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off.


MaxCyte is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status

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