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Protein Enzyme Scientist Jobs (NOW HIRING)

Medra

Research Associate - Protein

San Francisco, CA · On-site

Scientific AI that can analyze results, reason about next steps, and close the loop autonomously ... Experience with cell‑free protein expression or specialized enzyme workflows * Comfort working ...

Medra

Research Associate - Protein

San Francisco, CA · On-site

Scientific AI that can analyze results, reason about next steps, and close the loop autonomously ... Experience with cell-free protein expression or specialized enzyme workflows * Comfort working with ...

Edison Scientific, Inc.

$300/wk

About us Edison Scientific builds and deploys AI scientist agents to accelerate science and the ... Track record in protein optimization campaigns spanning antibody engineering, enzyme engineering ...

Cascade Bio

Process Development Scientist

Denver, CO · On-site

$110K - $150K/yr

Process Development Scientist Location: Denver, CO (on-site) Type: Full-time Cascade Biocatalysts ... Interface with protein engineering efforts, translating process bottlenecks into enzyme engineering ...

Cascade Bio

Process Development Scientist

Denver, CO

$110K - $150K/yr

Process Development Scientist Location: Denver, CO (on-site) Type: Full-time Cascade Biocatalysts ... Interface with protein engineering efforts, translating process bottlenecks into enzyme engineering ...

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Protein Enzyme Scientist information

What does a protein enzyme scientist do?

A Protein Enzyme Scientist studies the structure, function, and engineering of enzymes, which are proteins that catalyze biochemical reactions. They design and conduct experiments to analyze how enzymes work, improve their efficiency, and develop new enzyme-based applications for industries such as pharmaceuticals, biotechnology, and agriculture. Their work often involves using advanced laboratory techniques and collaborating with other scientists to solve complex biological problems.

What are the key skills and qualifications needed to thrive as a protein enzyme scientist?

To thrive as a Protein Enzyme Scientist, you need a solid background in biochemistry, molecular biology, and enzymology, typically supported by a PhD or master's degree in a related field. Experience with techniques such as protein purification, enzyme kinetics, mass spectrometry, and specialized software for structural analysis is often required. Strong analytical thinking, attention to detail, and effective collaboration skills help you excel in research and multidisciplinary team environments. These capabilities are essential for designing experiments, interpreting complex data, and advancing enzyme research for scientific or industrial applications.

What are some common challenges faced by protein enzyme scientists when scaling up enzyme production from the lab to industrial levels?

Protein Enzyme Scientists often encounter challenges such as maintaining enzyme stability and activity during large-scale production, optimizing expression systems, and ensuring consistent purity across batches. Scaling up can introduce variables like changes in temperature, pH, and mixing that may affect yield and performance. Collaboration with process engineers and quality control teams is crucial to troubleshoot issues and develop robust protocols for reliable industrial-scale enzyme manufacturing.

What is the difference between Protein Enzyme Scientist vs Biochemist?

AspectProtein Enzyme ScientistBiochemist
Required CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fields; Ph.D. often preferredBachelor's or Master's in Biochemistry, Chemistry, or related fields; Ph.D. common for research roles
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsAcademic labs, research institutions, industry settings
Employer & Industry UsagePharmaceutical, biotech, research organizations focusing on enzyme functionsUniversities, research institutes, industry roles in biological sciences

The main difference is that a Protein Enzyme Scientist specializes specifically in enzyme functions and applications, often focusing on enzyme design and activity, while a Biochemist has a broader scope in studying chemical processes in living organisms. Both roles require similar educational backgrounds and work environments, but their focus areas and job responsibilities differ based on specialization.

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Infographic showing various Protein Enzyme Scientist job openings in the United States as of September 2026, with employment types broken down into 4% Internship, 2% As Needed, 87% Full Time, 4% Part Time, and 3% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution.

Postdoctoral Researcher - Enzyme engineering for cell-free systems

Golden, CO • On-site

National Renewable Energy Laboratory
Scientific Research and Development Services • 1 - 5K employees
Learn more about National Renewable Energy Laboratoryexternal

$76K - $126K/yr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 24 days ago

Job description

Job Title

Postdoctoral Researcher – Enzyme Engineering for Cell‑Free Systems

Location

Golden, Colorado

Position Type

Postdoc (Fixed Term), 40 hours per week

Overview

RRES Center at NLR focuses on biological, chemical, and catalytic research in polymer design, upcycling, separations, synthetic biology, bioconversion, analytical sciences, computational modeling, and lignocellulosic chemistry. The successful candidate will work on the DOE‑funded project Integrating cell‑free systems and genome engineering to accelerate biosystems design for carbon‑negative biomanufacturing, developing optimized cell‑free systems for converting C1 substrates to sustainable biofuels and bioproducts.

Responsibilities
  • Identify, express, purify, and assay enzymes from full metabolic pathways.
  • Develop high‑throughput enzymatic assays to validate pathways.
  • Collaborate with data scientists to design efficient cell‑free production pathways.
  • Perform directed evolution, structure‑guided protein engineering, and machine‑learning‑guided protein engineering to improve enzyme and pathway function.
  • Conduct laboratory experiments safely and independently, with minimal supervision.
  • Plan and execute research in collaboration with multidisciplinary teams.
  • Communicate scientific results effectively in written and oral formats.
  • Author peer‑reviewed publications.
  • Work effectively in a large, multidisciplinary, multi‑institutional team of engineers and scientists.
Basic Qualifications
  • Recent PhD graduate within the last three years.
  • Experience with cloning, expression, and purification of proteins.
  • Experience with automation of biochemical assays.
  • Demonstrated experience in enzyme and/or protein engineering.
  • Ability to take initiative to set direction and goals for assigned tasks.
  • Strong troubleshooting and problem‑solving skills.
  • Strong record of quality peer‑reviewed publications.
  • Excellent safety record.
  • Ability to follow complex standard operating procedures with attention to detail.
Preferred Qualifications
  • Analytical chemistry experience with HPLC, GC‑FID, GC‑MS, and/or LC‑MS.
Annual Salary Range

$76,600 – $126,400

Benefits Summary
  • Medical, dental, and vision insurance.
  • Short‑term disability insurance.
  • Pension benefits.
  • 403(b) employee savings plan with employer match.
  • Life and accidental death and dismemberment insurance.
  • Personal time off and sick leave; paid holidays.
  • Possible performance‑, merit‑, and achievement‑based awards.
  • Possible relocation expense reimbursement.
Equal Opportunity Employer

All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity, genetic information, marital status, domestic partner status, military or veteran status, national origin, ancestry, race, religion, creed, sex, pregnancy, childbirth, breastfeeding, sexual orientation, or any other status protected by federal, state, or local law.

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