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Protein Engineering Jobs in Chicago, IL (NOW HIRING)

EVOZYNE INC

Applied AI Research Fellow

Chicago, IL · On-site

We are transforming how the industry approaches protein engineering. Our platform, EvoGen, is both generative and predictive. Rather than focusing on structure alone, we build models that learn how ...

Home Chef

Engineering Project Manager

Chicago, IL · On-site

Our Tempo menu includes options that are protein-packed, fiber-rich, calorie and carb conscious ... The Engineering Project Manager is an organized, detail-oriented self-starter who leads cross ...

Home Chef

Engineering Project Manager

Chicago, IL · On-site

Our Tempo menu includes options that are protein-packed, fiber-rich, calorie and carb conscious ... The Engineering Project Manager is an organized, detail-oriented self-starter who leads cross ...

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All JobsProtein Engineering JobsProtein Engineering Jobs in Chicago, IL

Protein Engineering information

See Chicago, IL salary details

$33.5K

$64.9K

$98.4K

How much do protein engineering jobs pay per year?

As of Aug 6, 2026, the average yearly pay for protein engineering in Chicago, IL is $64,876.00, according to ZipRecruiter salary data. Most workers in this role earn between $48,400.00 and $74,200.00 per year, depending on experience, location, and employer.

What is protein engineering?

A Protein Engineering job involves designing, modifying, and optimizing proteins for specific applications in medicine, biotechnology, and industry. Scientists in this field use computational modeling, directed evolution, and genetic engineering to enhance protein functions. Roles may include developing enzymes for drug production, improving therapeutic proteins, or creating biomaterials. This work often requires expertise in molecular biology, biochemistry, and structural biology.

What are the key skills and qualifications needed to thrive in protein engineering, and why are they important?

To thrive in Protein Engineering, you need a solid background in biochemistry, molecular biology, and genetic engineering, typically supported by a relevant advanced degree. Experience with laboratory techniques such as PCR, site-directed mutagenesis, protein expression/purification, and analytical tools like mass spectrometry or chromatography is essential. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help you stand out in this role. These competencies are crucial for designing novel proteins, collaborating in multidisciplinary teams, and ensuring successful project outcomes in biotech or pharmaceutical environments.

What are the typical daily responsibilities of someone working in protein engineering?

A typical day in Protein Engineering involves designing and conducting experiments to modify protein sequences, expressing and purifying proteins, and analyzing their structure or function using techniques like chromatography and spectroscopy. You will often document your results, troubleshoot unexpected findings, and present data to colleagues or project teams. Collaboration with scientists in molecular biology, bioinformatics, and structural biology is common to ensure robust experimental design and data interpretation. The role may also include literature reviews to stay updated with the latest research and participating in team meetings to plan next steps or project timelines.

How much do protein engineers make?

Protein engineers typically earn a median salary ranging from $70,000 to $120,000 annually, depending on experience, education, and location. Advanced skills in molecular biology, bioinformatics, and laboratory techniques can lead to higher compensation, especially in biotech or pharmaceutical industries.

What do protein engineers do?

Protein engineers design and modify proteins to improve their functions or create new ones, often using techniques like directed evolution and computational modeling. They work in research labs, utilizing tools such as gene editing and structural analysis to develop applications in medicine, agriculture, and industry.
What are the most commonly searched types of Protein Engineering jobs in Chicago, IL? The most popular types of Protein Engineering jobs in Chicago, IL are:
What are popular job titles related to Protein Engineering jobs in Chicago, IL? For Protein Engineering jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Protein Engineering jobs in Chicago, IL look for? The top searched job categories for Protein Engineering jobs in Chicago, IL are:
Protein Engineering jobs near you
Infographic showing various Protein Engineering job openings in Chicago, IL as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $64,876 per year, or $31.2 per hour.

Talent Community | Research Scientist

EVOZYNE INC

Chicago, IL • On-site

Full-time

Re-posted 23 days ago

Job description

Evozyne designs and builds engineered protein therapeutics using our AI-native platform, transforming what’s possible in immune-mediated disease treatment. Our scientists work at the intersection of biology, protein engineering, and AI to turn bold ideas into therapies that can meaningfully improve patients’ lives. This posting helps us connect with candidates for future opportunities. While this listing is not tied to a current opening, we encourage you to join our talent community so we can connect with you when new roles emerge!

Key Responsibilities

  • Design and execute experiments to discover and characterize protein-based therapeutic candidates for immunological targets

  • Develop, optimize, and interpret in vitro and cell-based assays to evaluate activity, mechanism, and selectivity

  • Collaborate cross-functionally with data science and computational teams to advance programs toward key milestones

  • Analyze complex datasets and translate findings into clear recommendations for next steps

  • Contribute to experimental strategy, study design, and troubleshooting to accelerate discovery timelines

  • Communicate results effectively in team meetings and written reports, supporting decision-making across projects

  • Stay current with emerging scientific literature and apply new approaches to strengthen our discovery platform

Who You Are

You thrive in an early-stage start-up environment and are motivated by the opportunity to build new medicines that can transform patients’ lives. You combine agility with scientific rigor to deliver high-quality results, and you bring natural curiosity and a collaborative mindset to solving complex challenges.

Background + Experience

  • Undergraduate and/or graduate level education focused on (molecular or cell) biology, protein sciences, immunology, biophysics, biochemistry, or a similar field.
  • Hands-on experience executing bench research in a scientific lab
  • Ability to analyze, interpret, and communicate experimental data


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