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Protein Engineering Jobs in Baltimore, MD (NOW HIRING)

Postdoctoral Fellowship

Baltimore, MD · On-site

$48K - $66K/yr

Description The Lin Lab in the Institute of NanoBiotechnology & Materials Science and Engineering ... Especially, the openings here are about the development of in-cellulo protein assemblies that can ...

For more than two decades, our expert scientists, engineers and business innovators have provided ... Protein Crystallography is advantageous. * Education and/or experience in sales is required.

For more than two decades, our expert scientists, engineers and business innovators have provided ... Protein Crystallography is advantageous. * Education and/or experience in sales is required.

Protein Engineering information

See Baltimore, MD salary details

$32.3K

$62.6K

$94.9K

How much do protein engineering jobs pay per year?

As of Aug 12, 2026, the average yearly pay for protein engineering in Baltimore, MD is $62,576.00, according to ZipRecruiter salary data. Most workers in this role earn between $46,700.00 and $71,500.00 per year, depending on experience, location, and employer.

What is protein engineering?

A Protein Engineering job involves designing, modifying, and optimizing proteins for specific applications in medicine, biotechnology, and industry. Scientists in this field use computational modeling, directed evolution, and genetic engineering to enhance protein functions. Roles may include developing enzymes for drug production, improving therapeutic proteins, or creating biomaterials. This work often requires expertise in molecular biology, biochemistry, and structural biology.

What are the key skills and qualifications needed to thrive in protein engineering, and why are they important?

To thrive in Protein Engineering, you need a solid background in biochemistry, molecular biology, and genetic engineering, typically supported by a relevant advanced degree. Experience with laboratory techniques such as PCR, site-directed mutagenesis, protein expression/purification, and analytical tools like mass spectrometry or chromatography is essential. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help you stand out in this role. These competencies are crucial for designing novel proteins, collaborating in multidisciplinary teams, and ensuring successful project outcomes in biotech or pharmaceutical environments.

What are the typical daily responsibilities of someone working in protein engineering?

A typical day in Protein Engineering involves designing and conducting experiments to modify protein sequences, expressing and purifying proteins, and analyzing their structure or function using techniques like chromatography and spectroscopy. You will often document your results, troubleshoot unexpected findings, and present data to colleagues or project teams. Collaboration with scientists in molecular biology, bioinformatics, and structural biology is common to ensure robust experimental design and data interpretation. The role may also include literature reviews to stay updated with the latest research and participating in team meetings to plan next steps or project timelines.

How much do protein engineers make?

Protein engineers typically earn a median salary ranging from $70,000 to $120,000 annually, depending on experience, education, and location. Advanced skills in molecular biology, bioinformatics, and laboratory techniques can lead to higher compensation, especially in biotech or pharmaceutical industries.

What do protein engineers do?

Protein engineers design and modify proteins to improve their functions or create new ones, often using techniques like directed evolution and computational modeling. They work in research labs, utilizing tools such as gene editing and structural analysis to develop applications in medicine, agriculture, and industry.
What are the most commonly searched types of Protein Engineering jobs in Baltimore, MD? The most popular types of Protein Engineering jobs in Baltimore, MD are:
What cities near Baltimore, MD are hiring for Protein Engineering jobs? Cities near Baltimore, MD with the most Protein Engineering job openings:
Infographic showing various Protein Engineering job openings in Baltimore, MD as of August 2026, with employment types broken down into 90% Full Time, 5% Part Time, 4% Contract, and 1% Nights. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $62,576 per year, or $30.1 per hour.

Postdoctoral Position in Jeffrey J. Gray's Computational Protein Structure and Design Lab

Johns Hopkins University

Baltimore, MD • On-site

$80K/yr

Full-time

Medical, Dental

Re-posted 21 days ago


Johns Hopkins University rating

8.0

Company rating: 8.0 out of 10

Based on 71 frontline employees who took The Breakroom Quiz

187th of 618 rated colleges and universities


Job description

Description
Are you excited to explore a yet-to-be-solved problem at the heart of AI-based protein engineering? Join Jeffrey Gray's research lab to develop and mature some of the most in-demand research skills in academia and industry today.
New approaches in deep neural networks are revolutionizing the study of protein structure, but so far these advances have not solved the critical issues to be able to design new therapeutic antibodies from scratch. The Gray lab is a leader in the study of protein-protein interactions and computational modeling of antibodies, including emerging deep learning approaches. This position will allow you to learn the emerging deep learning approaches to proteins and antibodies and craft new machine learning approaches for antibody engineering, protein-protein docking, and carbohydrate modeling. We create new methods and collaborate with academics and industry to apply these methods to important biological problems and to therapeutics. You will be a part of a dynamic, collaborative, and inclusive research group.
  • Highly competitive salary (up to $80,000 stipend) goes far in affordable Baltimore.
  • Full benefits including health insurance (coverage for eye and dental insurance).
  • The Gray laboratory is part of the Rosetta Commons (Prof. Gray serves as Director), and so you will be able to participate in Rosetta Conferences, workshops, and outreach.
  • Johns Hopkins offers an unmatched environment for life sciences research, with a dynamic community in biomolecular engineering, biophysics, biochemistry, and medicine.
  • Lab alumni have advanced to positions in industry giants (Genentech, Merck, Pfizer, GSK), and successful recent startups (Generate Bio, Outpace Bio).
  • Initial appointment period of one year, with expectation of 2-4 years total.
  • State-of-the-art computing infrastructure (NVIDIA H100 and A100 GPUs and CPUs for seamless computing).
  • Supportive mentoring environment, with regular 1:1 meetings and Individual Development Plans every 6 months.

More information about the Gray lab at http://graylab.jhu.edu
Key responsibilities could include, but are not limited to, assisting in the following:
  • Review literature on biomolecular structure and design technologies and deep learning approaches.
  • Assess gaps in current tools.
  • Assess of emerging deep learning methods for application in biomolecular engineering.
  • Create of novel deep learning tools for biomolecular engineering, including assembling novel data sets, building new architectures, training and assessing models.
  • Critically assess of biomolecular designs using multiple deep learning tools, physics-based models, and structural analysis.
  • Plan collaboration with experimentalists, to best assess competing design strategies.
  • Write journal articles and presentations for sharing the outcomes.

Qualifications
  • PhD in Engineering, biophysics, computational biology, or related field
  • Experience with scientific algorithm development, protein biophysics or engineering, protein structure prediction and design.
  • Experience in solving complex scientific or engineering problems
  • Excellent writing and communication skills
  • Ability to work in teams and contribute to a supportive and collaborative work culture

Application Instructions
In Interfolio, applicants should upload a CV, a brief statement of purpose, a code sample, and 2-3 representative publications (preprints acceptable). The statement should state why the Gray lab is a good fit for your career trajectory. The code sample can be a file or a few files or a link (e.g. a Github repository) that demonstrates your coding level.
Applications will be considered until the positions are filled.

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About Johns Hopkins University

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Gilman believed that teaching and research go hand in hand—that success in one depends on success in the other—and that a modern university must do both well. He also believed that sharing our knowledge and discoveries would help make the world a better place. In 145 years, we haven’t strayed from that vision. This is still a destination for excellent, ambitious scholars and a world leader in teaching and research. Distinguished professors mentor students in the arts and music, humanities, social and natural sciences, engineering, international studies, education, business, and the health professions. Those same faculty members, along with their colleagues at the university’s Applied Physics Laboratory, have made us the nation’s leader in federal research and development funding every year since 1979. That’s a fitting distinction for America’s first research university, a place that has revolutionized higher education in the U.S. and continues to bring knowledge and discoveries to the world.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Baltimore, MD, US

Year founded

1876