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Prompt Engineer Jobs in Natick, MA (NOW HIRING)

Prompt Engineering * AI Output Evaluation * Technical Documentation * Technical & Professional Writing * Content Review & Editing * Data Annotation * Fact Checking * Independent Research * Business ...

Design, develop, and deploy enterprise AI solutions from concept through production, leveraging large language models (LLMs), AI agents, prompt engineering, and Retrieval-Augmented Generation (RAG)

Prompt Engineering * AI Output Evaluation * Technical Documentation * Technical & Professional Writing * Content Review & Editing * Data Annotation * Fact Checking * Independent Research * Business ...

Prompt Engineering * AI Output Evaluation * Technical Documentation * Technical & Professional Writing * Content Review & Editing * Data Annotation * Fact Checking * Independent Research * Business ...

Expertise in prompt engineering, retrieval pipelines, and modular AI system design. * Strong background in engineering data workflows, including structured and unstructured data integration.

Senior Software Engineer

Boston, MA · On-site

$133K - $175K/yr

... prompt engineering, agentic loop design, and retrieval-augmented generation (RAG). • Experience driving coordinated action between cross-functional teams (product, research, stakeholders) working ...

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Word Expert - Remote

Boston, MA · Remote

$30 - $50/hr

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Excel Expert - Remote

Boston, MA · Remote

$30 - $50/hr

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Excel Expert - Remote

Boston, MA · Remote

$30 - $50/hr

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Use prompt engineering and AI tools to test and improve model performance. * Collaborate with project teams and maintain high-quality documentation. Required Qualifications * 3+ years of professional ...

New

Showing results 41-60

Prompt Engineer information

See Natick, MA salary details

$10

$48

$90

How much do prompt engineer jobs pay per hour?

As of Aug 23, 2026, the average hourly pay for prompt engineer in Natick, MA is $48.61, according to ZipRecruiter salary data. Most workers in this role earn between $36.97 and $62.79 per hour, depending on experience, location, and employer.

What is a prompt engineer?

A Prompt Engineer is a professional who designs, refines, and optimizes prompts to improve interactions with AI models, such as ChatGPT. Their role involves understanding model behavior, crafting precise queries, and experimenting with phrasing to achieve desired outputs. They may work in AI research, software development, or content generation to maximize AI efficiency. Strong skills in language, logic, and sometimes coding are essential for success in this role.

What does a prompt engineer do?

A typical day for a Prompt Engineer involves designing, testing, and refining prompts to enhance the performance of AI language models, often collaborating closely with data scientists, software engineers, and product managers. You might analyze the results of model outputs, integrate user or stakeholder feedback, and iterate on prompt strategies to solve diverse business challenges. Your role will usually include documentation, troubleshooting, and keeping up with the latest advances in AI technologies. Expect a mix of independent work and regular team meetings in a dynamic, fast-evolving environment focused on innovation and improvement.

What skills and qualifications are needed to be a prompt engineer?

To thrive as a Prompt Engineer, you need a strong grasp of natural language processing (NLP), machine learning concepts, and experience crafting effective prompts for large language models, usually supported by a technical degree or relevant experience. Familiarity with tools such as OpenAI's API, Hugging Face, or other AI platforms, as well as knowledge of programming languages like Python, is highly valuable. Creative thinking, analytical problem-solving, and cross-functional communication skills help differentiate top candidates in this field. These abilities are crucial for optimizing AI outcomes and ensuring collaboration with both technical and non-technical teams.

Are prompt engineers still in demand?

Prompt engineers are currently in demand as organizations seek professionals skilled in designing effective prompts for AI language models. The role often requires knowledge of natural language processing, machine learning, and familiarity with AI tools like GPT. Demand is expected to grow as AI integration expands across industries.

How much do prompt engineers make?

Prompt engineers typically earn between $80,000 and $150,000 annually, depending on experience, location, and industry. Senior roles or those with specialized skills in AI and machine learning can command higher salaries, especially in tech hubs or companies investing heavily in AI development.

What exactly is prompt engineer work?

A prompt engineer designs and optimizes prompts used to interact with AI language models, ensuring accurate and relevant responses. This role involves understanding AI behavior, crafting clear instructions, and often requires knowledge of machine learning, programming, or data analysis.

What are popular job titles related to Prompt Engineer jobs in Natick, MA?

For Prompt Engineer jobs in Natick, MA, the most frequently searched job titles are:

What job categories do people searching Prompt Engineer jobs in Natick, MA look for?

The top searched job categories for Prompt Engineer jobs in Natick, MA are:

What cities near Natick, MA are hiring for Prompt Engineer jobs?

Cities near Natick, MA with the most Prompt Engineer job openings:

Infographic showing various Prompt Engineer job openings in Natick, MA as of August 2026, with employment types broken down into 87% Full Time, 9% Part Time, and 4% Contract. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution, with an average salary of $101,111 per year, or $48.6 per hour.

Principal Engineer, AI Authoring

Vertex Pharmaceuticals

Boston, MA • On-site

$166.64 - $250/hr

Other

Medical, Dental, Vision, Retirement, PTO

Re-posted 14 days ago


Vertex Pharmaceuticals rating

6.5

Company rating: 6.5 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

78th of 86 rated pharmaceutical


Job description

## Principal Engineer, AI AuthoringApplylocations: Boston, MAtime type: Full timeposted on: Posted Todayjob requisition id: REQ-28761**Job Description****Position Summary**:We are seeking a highly skilled and visionary Principal Engineer, AI Authoring to join our AI Authoring Platform team. Reporting to the Director of AI Authoring Platform, you will lead the design, development, and optimization of Vertex’s AI-driven content generation engine. This role is pivotal in shaping the technical architecture of our platform, ensuring the performance, accuracy, and scalability of our LLM-powered authoring tools. You will tackle complex engineering challenges, including automated document workflows and Retrieval-Augmented Generation (RAG)-based architectures, to support the creation of high-quality, compliant, and efficient regulatory documents.**Key Duties and Responsibilities*** Design and maintain the end-to-end technical architecture for AI-assisted document generation, focusing on modular LLM integration, prompt engineering, and retrieval pipelines, while partnering closely with the AI Architect to ensure alignment with enterprise standards and scalability.* Build and optimize sophisticated Retrieval-Augmented Generation (RAG) systems that accurately pull from vast clinical and regulatory data sources to assist in document creation.* Engineer the data connectors and transformations required to feed structured and unstructured data into AI models for automated document population.* Develop and implement automated testing and validation frameworks to ensure AI-authored outputs meet the strict safety and compliance standards of the Life Sciences industry.* Rapidly prototype new AI authoring features, such as automated summarization or cross-document consistency checks, to determine technical viability before full-scale development.* Serve as the final escalation point for complex technical blockers, from debugging model hallucinations to optimizing cloud infrastructure for high-compute AI workloads.**Knowledge and Skills*** Proven experience in designing and implementing AI-driven platforms, particularly those leveraging LLMs and RAG architectures.* Expertise in prompt engineering, retrieval pipelines, and modular AI system design.* Strong background in engineering data workflows, including structured and unstructured data integration.* Experience with automated testing and validation frameworks, particularly in regulated industries.* Proficiency in cloud infrastructure optimization for AI workloads.* Exceptional problem-solving skills, with the ability to address complex technical challenges.* Strong collaboration and communication skills to work effectively with cross-functional teams* Familiarity with the Life Sciences industry and its compliance requirements (preferred).* Experience with automated document workflows and AI-based content generation (preferred).**Education and Experience*** 8+ years of experience in software engineering, with a focus on AI, machine learning, or technical platform development.* Proven track record of leading the design and implementation of AI-driven systems, including LLM-based platforms and RAG architectures.* Bachelor’s or Master’s degree in Computer Science, Artificial Intelligence, Data Science, or a related technical field.* Hands-on experience with cloud platforms (e.g., AWS, Azure, or GCP) and distributed computing systems.* Demonstrated expertise in building and deploying production-grade AI/ML systems in complex, data-intensive environments.* Experience working in regulated industries, such as Life Sciences, is a strong plus.**Why Join Us?**At Vertex, you will have the opportunity to work on cutting-edge technologies that make a real difference in people’s lives. We offer a collaborative and innovative work environment, competitive compensation, and opportunities for professional growth.If you are passionate about leveraging AI to revolutionize content generation and thrive in solving complex engineering challenges, we encourage you to apply and join our mission to transform lives through innovation.#LI-HYBRID**Pay Range:**$166,640 - $250,000**Disclosure Statement:**The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Flex Designation:**Hybrid-Eligible Or On-Site Eligible**Flex Eligibility Status:**In this Hybrid-Eligible role, you can choose to be designated as: 1. **Hybrid**: work remotely up to two days per week; **or select** 2. **On-Site**: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #J-18808-Ljbffr

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