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Process Operators Jobs in Houston, PA (NOW HIRING)

Metals USA

Saw Operator

Ambridge, PA · On-site

$22 - $24/hr

Positions work pieces for processing, operating a single point machine to process work pieces by cutting, sawing and grinding. * Uses gauges, calipers indicators or rulers for measurement. * Programs ...

Metals USA Holdings Corp.

Saw Operator

Ambridge, PA

$22 - $24/hr

Positions work pieces for processing, operating a single point machine to process work pieces by cutting, sawing and grinding. * Uses gauges, calipers indicators or rulers for measurement. * Programs ...

Metals USA Holdings Corp.

Saw Operator

Ambridge, PA · On-site

$22 - $24/hr

Positions work pieces for processing, operating a single point machine to process work pieces by cutting, sawing and grinding. * Uses gauges, calipers indicators or rulers for measurement. * Programs ...

Xylem

Sales Process Specialist

Pittsburgh, PA · On-site +1

$65K - $85K/yr

As a leading water technology company with 23,000 employees operating in over 150 countries, Xylem ... The Sales Process Specialist is responsible for supporting and improving sales and commercial ...

Xylem

Sales Process Specialist

Pittsburgh, PA · On-site

$65K - $85K/yr

As a leading water technology company with 23,000 employees operating in over 150 countries, Xylem ... The Sales Process Specialist is responsible for supporting and improving sales and commercial ...

ATI

Process Controls and Automation Engineer

Pittsburgh, PA · On-site

$81K - $104K/yr

Apply advanced engineering principles and process control strategies to improve operating efficiency of new and existing automation systems * Partner with cross-functional teams to implement process ...

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How much do process operators jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for process operators in Houston, PA is $19.44, according to ZipRecruiter salary data. Most workers in this role earn between $16.78 and $21.20 per hour, depending on experience, location, and employer.
Process & Automation Equipment Engineer

Process & Automation Equipment Engineer

Krystal Biotech

Pittsburgh, PA • On-site

Full-time

Re-posted 4 days ago

Job description

Process & Automation Equipment Engineer
About Krystal Bio: At Krystal Biotech, we bring together the brightest and most eager minds to relentlessly pursue the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs.
Founded in 2016, Krystal is distinguished in three powerful ways: science and technology using our patented gene therapy platform, innovative manufacturing supported by our commercial scale facilities, and a unique commercialization model that focuses on the patient’s end-to-end experience.
Krystal received U.S. FDA approval for the first and only redosable gene therapy treatment, VYJUVEK®, for the treatment of Dystrophic Epidermolysis Bullosa (DEB). Krystal continues to leverage our proprietary platform to rapidly advance a robust pipeline of investigational genetic medicines in respiratory, oncology, dermatology, and ophthalmology.
Krystal is headquartered in Pittsburgh, PA, which is home to our two state-of-the-art CGMP manufacturing facilities with teams around the world and satellite offices in Switzerland, Germany, and Japan. We are a company built and run by people who care, are fearless in the face of a challenge, love the work they do, and practice the highest level of scientific integrity. As we grow, we are seeking team members that embody these values.
Job Description Summary:
Krystal Biotech is seeking a motivated and data-driven manufacturing engineer to lead troubleshooting efforts and optimization of GMP manufacturing processes.  The Engineer will integrate process engineering, automation, and data analytics, while supporting the development of data-driven monitoring and predictive maintenance programs, along with intelligent manufacturing capabilities. This role is ideal for an engineer with a passion for automation and process optimization, with interest in becoming a subject matter expert on the control systems that drive our gene therapy manufacturing platform. This role serves as a technical bridge between Manufacturing, Automation, and Facilities, ensuring seamless integration of process equipment, control systems maintenance, and facility infrastructure.
Primary Responsibilities:
  • Act as the primary interface between Manufacturing, Automation, and Facilities teams to diagnose and resolve process and equipment issues spanning control systems, utilities, and unit operations.
  • Support day-to-day upstream manufacturing operations, ensuring equipment and processes are operating within validated parameters.
  • Develop deep familiarity with control systems (PLCs, HMIs, and SCADA) associated with manufacturing processes with a long-term goal to predictive maintenance of process equipment
  • Partner with the Automation and Facilities teams to troubleshoot issues across process equipment, control systems, and supporting utilities (HVAC, gases, etc.)
  • Identify opportunities to optimize existing automation configurations, batch record workflows, and data collection tools to improve process efficiency and data integrity.
  • Assist in the authoring and review of SOPs, batch records, work orders, change controls, and deviations related to upstream process and automation activities.
  • Support equipment qualification, process validation, and technology transfer activities as they relate to upstream systems and associated control infrastructure.
  • Collaborate with Process Development and Manufacturing Sciences to ensure alignment between process design intent and real-world automation behavior.
  • Contribute to continuous improvement initiatives and help foster a culture of proactive problem-solving across CMC functions.

Minimum Qualifications & Desired Competencies:
  • Bachelor's degree in Engineering, or a relevant technical field
  • Prior experience in a regulated manufacturing or process engineering environment is preferred (biotech, pharmaceutical, or adjacent industry)
  • Exposure to industrial automation systems such as PLCs, HMIs, and/or SCADA platforms; hands-on experience is a plus
  • Familiarity with GMP principles and documentation standards
  • Background in upstream bioprocessing, cell culture, or bioreactor operations is a plus
  • Solid process engineering background in biologics / CGT GMP manufacturing
  • Hands-on experience with process equipment troubleshooting (e.g., Bioreactors/ skids/ fillers/ mixers and single-use systems)
  • Working knowledge of process controls and automation systems (hands-on experience with at least one platform preferred)
    • PLC (Allen-Bradley, Siemens) or equivalent
    • SCADA (FactoryTalk SE / Ignition / DeltaV) or equivalent
    • HMI (FactoryTalk ME / TIA Portal) or equivalent
  • Demonstrated experience with instrument or equipment control application software. SME level preferred.
  • Basic understanding of facilities/utilities systems (HVAC, cleanrooms)
  • Experience with process data and historians (e.g., OSI PI) and Familiarity with data analysis tools (e.g., Excel, Python, or similar)
  • Interest in applying data analytics for troubleshooting and process improvement
  • Exposure to predictive maintenance or anomaly detection is a plus
  • Awareness of advanced process control or model-based approaches (nice-to-have)
  • Strong troubleshooting mindset for real-time manufacturing support, Experience with root cause analysis (RCA, FMEA), Familiarity with deviation/CAPA processes in GMP environments and Ability to operate effectively at the interface of process, automation, and facilities teams
  • Strong cross-functional collaboration (MSAT, QA, Facilities, IT) and Ability to translate process issues into data-driven insights
  • Interest in supporting digital / smart manufacturing initiatives
  • Strong analytical and troubleshooting skills with a methodical, detail-oriented approach
  • Ability to work collaboratively across functions and communicate effectively with both technical and non-technical stakeholders
  • Self-starter who can manage competing priorities in a fast-paced, evolving environment
  • Excellent written and oral communication skills

Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc.  will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc. 

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