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Process Development Scientist Jobs in Massachusetts

Amgen

Process Development Senior Scientist

Cambridge, MA · On-site

$100K - $136K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Process Development Senior Scientist What you will do Let'sdo this.Let'schange the world. In this vital role you willbe responsible fordevelopment, characterization, scale-up and support of drug ...

Amgen

Process Development Principal Scientist

Cambridge, MA

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Process Development Principal Scientist What you will do Let's do this. Let's change the world. In this vital role you will joining Amgen's Attribute Sciences (AS) department within the Process ...

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$22

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$67

How much do process development scientist jobs pay per hour?

As of Aug 17, 2026, the average hourly pay for process development scientist in Massachusetts is $42.23, according to ZipRecruiter salary data. Most workers in this role earn between $30.96 and $50.38 per hour, depending on experience, location, and employer.

What is a process development scientist?

A Process Development Scientist is a professional who designs, develops, and optimizes processes for manufacturing products, typically in industries like pharmaceuticals, biotechnology, or chemicals. Their work involves scaling up laboratory procedures to full production, improving efficiency, ensuring quality, and meeting regulatory standards. They collaborate with research, engineering, and manufacturing teams to implement new processes or refine existing ones. Process Development Scientists play a critical role in bringing new products from the research phase to commercial production while maintaining safety and compliance.

What are the key skills and qualifications needed to thrive as a process development scientist?

To thrive as a Process Development Scientist, you need a background in chemistry, biochemistry, or chemical engineering, supported by at least a bachelor’s (often master’s or PhD) degree and experience in laboratory research. Familiarity with analytical instrumentation (such as HPLC, GC, and mass spectrometry), process modeling software, and relevant regulatory standards is crucial. Strong problem-solving, collaboration, and communication skills help drive innovation and coordinate with cross-functional teams. These skills ensure the efficient development and scale-up of robust, safe, and cost-effective processes in pharmaceutical, biotech, or chemical manufacturing environments.

What are some typical challenges faced by process development scientists when scaling up from lab experiments to full production?

Process Development Scientists often encounter challenges when transitioning processes from the laboratory to large-scale production. These can include maintaining product quality and consistency, optimizing yields, and ensuring that processes are cost-effective at scale. Addressing equipment differences, process variability, and regulatory compliance are also common hurdles. Collaboration with engineers, manufacturing teams, and quality assurance professionals is essential to successfully navigate these challenges and achieve scalable, robust processes.

What are popular job titles related to Process Development Scientist jobs in Massachusetts?

For Process Development Scientist jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Process Development Scientist jobs in Massachusetts look for?

The top searched job categories for Process Development Scientist jobs in Massachusetts are:

What cities in Massachusetts are hiring for Process Development Scientist jobs?

Cities in Massachusetts with the most Process Development Scientist job openings:

Process Development Scientist jobs near you
Infographic showing various Process Development Scientist job openings in Massachusetts as of July 2026, with employment types broken down into 1% As Needed, 85% Full Time, 12% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $87,828 per year, or $42.2 per hour.

DOWNSTREAM PROCESS DEVELOPMENT SCIENTIST

MyGradJob

Billerica, MA

Full-time

Re-posted 24 days ago

Job description

Company Description

MilliporeSigma is the North American life science brand of Merck KGaA, Darmstadt, Germany - a leading science and technology company. It offers a broad range of innovative products and services to biotech and pharmaceutical drug therapies businesses. Through dedicated collaboration with the scientific and engineering communities, and as one of the top three R&D investors in the life science tools industry, the brand serves as a strategic partner to customers and helps advance the promise of life science.

Job Description
  • Design fit-for-purpose purification experiments according to the stage of development
  • Ensure scientific evaluation of impact of deviations to Downstream validation studies
  • Compile and analyze experimental data to generate process knowledge and decide on next steps
  • Write development and validation reports and ensure their timely delivery
  • Prepare and present project updates to global project team and to upper management
  • Ensure a continuous improvement within Downstream process development activities
  • Represent & promote E2E and Biodevelopment activities (presentations, congresses, events)
  • Technical lead on the overall projects (supervises Downstream processes development and implementation of new methods and services)
  • Technical leader for equipment, technologies for Downstream process development
  • Responsible for activities ranging from protein purification, filtration, biochemical and biophysical characterization of proteins: -
  • Execute routine protein purification with affinity, size exclusion, ion exchange, and hydrophobic interaction chromatography using AKTA systems (Unicorn software)
  • Perform analyses including but not limited to SDS-PAGE, SE-HPLC, LAL, host cell-DNA, host cell protein, as necessary
  • To develop, validate and transfer robust analytical methods required for successful drug development and manufacturing.
  • To support follow-up and troubleshooting on analytical methods.
  • Provide expertise and insight to guide development of appropriate purification methods
  • Develop novel purification processes as well as using standard methods to purify proteins from the mg to gram scale. Processes will be multiple steps and must provide necessary clearance of viruses, endotoxin, and host cell proteins and DNA.
  • Perform, develop and optimize robust, efficient, scalable strategies for improving process performance. Activities will include small-scale studies and pilot scale purification studies.
  • Apply DOE methods to purification activities
Qualifications
  • Engineering/Master degree (PhD preferred) in biotechnology with 5+ years in the biopharmaceutical industry
  • Solid and proven theoretical basis and hands-on experience in protein purification and analytical characterization
  • Hands-on experience with purification unit operations including filtration, chromatography, TFF, UF/DF, AKTA, UNICORN and HPLC systems.
  • Strong hands-on experience in troubleshooting and routine instrument maintenance.
  • Experienced in protein purification via affinity, hydrophobic interaction (HIC), ion exchange (IEX), size exclusion (SEC) and mixed-mode chromatography
  • Knowledge and skills in biochemical characterization of proteins including analytical and biophysical
  • Proven track record in Purification Process Development is necessary with emphasis on chromatographic separations and excellent understanding of and experience with chromatographic resin screening and process optimization.  Experience with scale-up and GMP manufacturing is desirable.
  • Solid and proven working knowledge of DOE. Ability to critically analyze data using statistical tools and to compile technical reports
  • Excellent presentation and communication skills
  • Results-oriented with ability to work and deliver under pressure
  • Excellent English (written, oral) 
Additional Information

All your information will be kept confidential according to EEO guidelines.

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