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Principal Research Analyst Jobs (NOW HIRING)

Principal Research Scientist

Seattle, WA · On-site

$108.85 - $133.04/hr

About this OpportunityReporting to Professor, the Research Scientist Principal is responsible for ... analyses, and interpretation) and producing presentations and peer-review publications. This ...

About this Opportunity Reporting to Professor, the Research Scientist Principal is responsible for ... analyses, and interpretation) and producing presentations and peer-review publications. This ...

Legal Research Analyst Employment Type: Full-Time, Part-Time, Temporary and Permanent JOB SUMMARY ... PRINCIPAL DUTIES AND RESPONSIBILITIES • Delivers timely, high quality legal and business research ...

... principal investment firm. We are a unique company in that we have advised the buyer on every one ... Additionally, Research Analysts will eventually be expected to train/manage interns and other ...

... principal investment firm. We are a unique company in that we have advised the buyer on every one ... Additionally, Research Analysts will eventually be expected to train/manage interns and other ...

PRINCIPAL ACCOUNTABILITIES: * This role identifies, tracks, segments, and analyzes donor records ... The Prospect Research Analyst must keep current on research and fundraising trends through regular ...

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Principal Research Analyst information

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$38.5K

$74K

$99.5K

How much do principal research analyst jobs pay per year?

As of Aug 9, 2026, the average yearly pay for principal research analyst in the United States is $73,965.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,000.00 and $98,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a principal research analyst, and why are they important?

To thrive as a Principal Research Analyst, you need advanced analytical abilities, deep expertise in your subject area, and typically a graduate degree in a relevant field such as economics, business, or data science. Proficiency in data analysis software (such as SPSS, SAS, or R), quantitative and qualitative research methodologies, and experience with visualization tools are commonly required. Strong communication, critical thinking, and leadership skills help you present findings clearly and guide research teams effectively. These abilities ensure high-quality, actionable insights that drive strategic decision-making for organizations.

What is the difference between Principal Research Analyst vs Senior Research Analyst?

AspectPrincipal Research AnalystSenior Research Analyst
Required CredentialsBachelor's or Master's degree in relevant field; often requires experience in research methodsBachelor's or Master's degree; significant research experience preferred
Work EnvironmentLead research projects, analyze data, develop strategies, often in corporate or consulting settingsConduct research, analyze data, support project teams in various industries
Employer & Industry UsageUsed in corporate, consulting, and government sectors for senior research rolesCommon in market research, healthcare, finance, and academic sectors

The Principal Research Analyst typically holds a higher level of responsibility, leading research initiatives and making strategic decisions. The Senior Research Analyst supports these efforts with detailed analysis and data collection. Both roles require strong analytical skills and relevant education, but the Principal role involves more leadership and strategic planning.

How does a principal research analyst typically collaborate with cross-functional teams within an organization?

Principal Research Analysts frequently work with cross-functional teams, such as product development, marketing, and executive leadership, to provide data-driven insights that inform strategic decisions. They often lead meetings to present findings, translate complex research into actionable recommendations, and ensure alignment between research outcomes and business objectives. Collaboration may involve managing junior analysts, coordinating with external partners, and facilitating workshops to integrate research insights into broader organizational initiatives. This collaborative environment fosters a dynamic workflow and offers opportunities to influence high-level decisions.

What is a principal research analyst?

Principal Research Analysts are senior professionals who lead and oversee research projects within organizations, often in fields like business, technology, healthcare, or government. They are responsible for designing research methodologies, analyzing complex data, and providing strategic insights to inform decision-making. Their role also involves mentoring junior analysts, presenting findings to stakeholders, and ensuring research quality and integrity. Principal Research Analysts typically have advanced degrees and significant experience in their area of expertise.
More about Principal Research Analyst jobs
What job categories do people searching Principal Research Analyst jobs look for? The top searched job categories for Principal Research Analyst jobs are:
Infographic showing various Principal Research Analyst job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 11% Part Time, and 2% Contract. Highlights an 87% Physical, 3% Hybrid, and 10% Remote job distribution, with an average salary of $73,965 per year, or $35.6 per hour.

Analytical Development Principal Research Associate

Vrtx

Boston, MA • On-site

$100K - $128K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 13 days ago


Job description

Job Description

Job Title: Analytical Development Principal Research Associate

Job Location: 316-318 Northern Ave, Boston, 02210

Openings: 1

Job Type: Full Time

Duties:

  • Design, develop, execute and analyze characterization and release assays for identity, purity, strength and potency of cell- based products. Multiple analytical platforms will be employed including RT-qPCR, SDS-PAGE, ELISA, Western blots, Flow cytometry, Flow-cam, ddPCR, Alphalisa and cell- based functional/ potency assays.
  • Execute test methods in support of pluripotent stem cell Process Development activities.
  • Troubleshoot, optimize, and trend assay performance.
  • Report on project progress, write analytical development protocols and reports, provide recommendations to management.
  • Identify, qualify, and manage analytical reagents as per regulatory standards.
  • Establish assay design criteria using Design of Experiments (DOE) and other contemporary development tools.
  • Perform statistical analysis to establish specificity, sensitivity, linear range, precision, and accuracy of test methods.
  • Establish reference standard materials as required to support assay validation.
  • Transfer assays to QC and provide SME support for assay qualification, author transfer/qualification protocols and reports.
  • Maintain excellent written documentation (e.g. lab notebook and test forms).

Requirements:

  • Employer will accept a Master's degree in Biochemistry, Cell & Molecular Biology, Pharmacology and Toxicology or a related field and 2 years of experience in the job offered or in a Analytical Development Principal Research Associate-related occupation.
  • Alternatively, employer will accept a Bachelor's degree Biochemistry, Cell & Molecular Biology, Pharmacology and Toxicology or a related field and 6 years of experience in the job offered or in a Analytical Development Principal Research Associate-related occupation.
  • Position requires demonstrable experience in the following:
  • Developing analytical methods in compliance with ICH guidelines. Assisting with the following assay platforms: RT-qPCR, ELISA, Western blots, Flow cytometry or cell- based functional/ potency assays. Assisting with the culture of multiple mammalian cell types and combination drug product (Cells + device) Using literature to design proof of concept studies. Writing technical documents including development reports, qualification protocols and qualification reports.

Rate of Pay: $100,755.00 to $128,500.00 per year

CONTACT: Send Resume to futuretalent@vrtx.com. Reference 12140.579. EOE.

Pay Range:

$0 - $0

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com