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Principal Process Safety Engineer Jobs in Indiana

Covestro

Process Engineer

Frankfort, IN · On-site

The Process Engineer provides technical support to unit operations, contributing to efforts that ... Provides technical and process safety input to MOC committee. Delivers operator training for ...

Covestro AG

Process Engineer

Frankfort, IN · On-site

The Process Engineer provides technical support to unit operations, contributing to efforts that ... Provides technical and process safety input to MOC committee. Delivers operator training for ...

Evonik

Process Controls Engineer

Lafayette, IN · On-site

Design, implement, and maintain control system safety requirements based on process safety ... Chemical or Electrical Engineering preferred * 3+ years of process controls and plant experience ...

Evonik

Senior Automation Engineer - SIS

Lafayette, IN

$100K - $131K/yr

The Senior Automation Engineer - SIS provides support to Tippecanoe production and support areas ... Design, implement and maintain control systems safety requirements as indicated through process ...

MonoSol

Process Scale up Engineer

La Porte, IN · On-site

The Process Scale Up Engineer is a hands on technical role responsible for the successful scale up ... Support site Safety Programs through participation in audits, investigations, Gemba walks, and ...

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Showing results 41-60

All JobsPrincipal Process Safety Engineer JobsPrincipal Process Safety Engineer Jobs in Indiana

Principal Process Safety Engineer information

See Indiana salary details

$82.8K

$142.8K

$173.7K

How much do principal process safety engineer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for principal process safety engineer in Indiana is $142,813.00, according to ZipRecruiter salary data. Most workers in this role earn between $123,700.00 and $161,300.00 per year, depending on experience, location, and employer.

What is the difference between Principal Process Safety Engineer vs Process Safety Engineer?

AspectPrincipal Process Safety EngineerProcess Safety Engineer
CredentialsTypically requires advanced certifications like API, NEBOSH, or equivalent, along with extensive industry experienceRequires relevant engineering degree and safety certifications, often less extensive experience needed
Work EnvironmentLeads safety programs, reviews safety protocols, and mentors teams in industrial settingsSupports safety assessments, implements safety procedures, and assists in risk analysis
Employer & Industry UsageUsed in large oil & gas, chemical, and petrochemical companies for senior safety rolesCommon in similar industries for safety support roles at various levels

The main difference is that the Principal Process Safety Engineer holds a senior leadership role with strategic responsibilities, while the Process Safety Engineer focuses on implementing safety measures and supporting safety protocols. Both roles require relevant certifications and industry experience, but the principal position involves more oversight and mentorship.

Principal Process Safety Engineer jobs near you
Infographic showing various Principal Process Safety Engineer job openings in Indiana as of August 2026, with employment types broken down into 95% Full Time, and 5% Nights. Highlights an 100% In-person job distribution, with an average salary of $142,813 per year, or $68.7 per hour.

Principal Technical Operations Engineer (Radiopharmaceuticals)

Cardinal Health, Inc.

Indianapolis, IN • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 10 hours ago

Cardinal Health rating

7.8

Company rating: 7.8 out of 10

Based on 337 frontline employees who took The Breakroom Quiz

131st of 887 rated healthcare providers

Job description

Job Summary
The Principal Technical Operations Engineer (Radiopharmaceuticals) is responsible for leading and managing the development, implementation, and continuous improvement of processes within radiopharmaceutical operations. This role is critical for ensuring product quality, regulatory compliance, and operational efficiency. The Principal Technical Operations Engineer will serve as a Subject Matter Expert (SME) for all process-related questions, actively manage Non-Conformance Reports (NCRs), Corrective and Preventive Actions (CAPAs), and Change Controls, and directly assist operations to achieve excellence in radiopharmaceutical manufacturing and support. The Principle Engineer will also create new processes such as Master Batch Records for clients as they onboard to the CMC facility.
Responsibilities
  • Applies comprehensive knowledge and a thorough understanding of concepts, principles, and technical capabilities to perform varied tasks and projects related to radiopharmaceutical processes.
  • Leads the creation, optimization, and documentation of new and existing operational processes for radiopharmaceuticals, ensuring alignment with ISO 13485 and 21 CFR 820 Quality System Regulations.
  • Manages and drives the resolution of Non-Conformance Reports (NCRs) by investigating root causes, implementing corrective actions, and ensuring process adjustments prevent recurrence.
  • Initiates, investigates, and manages Corrective and Preventive Actions (CAPAs) related to process deviations, quality issues, and operational improvements, ensuring timely and effective closure.
  • Oversees and executes the Change Control process for radiopharmaceutical operations, ensuring all proposed changes to processes, equipment, or materials are properly documented, assessed, approved, and implemented in compliance with regulatory requirements.
  • Serves as the primary Subject Matter Expert (SME) for all process-related questions, providing guidance and training to operations teams and cross-functional partners.
  • Actively assists operations in troubleshooting process issues, implementing process changes, and ensuring consistent execution of established procedures.
  • Involves in continuous improvement activities, identifying opportunities for process enhancements that increase efficiency, reduce waste, and improve product quality within radiopharmaceutical operations.
  • Identifies and implements data analysis to monitor process performance, ensure finished goods meet standards and specifications, and drives necessary changes to operational processes.
  • Supports Operations, Quality Control, Quality Assurance and Program Management teams by providing process expertise and ensuring process documentation supports compliance.
  • Performs activities related to Risk Management Plan, Risk Assessments with a focus on process-related risks in radiopharmaceutical production such as Master Batch Records and Master Packaging Records.
  • May contribute to the development of policies and procedures directly impacting radiopharmaceutical operations and process control.
  • Develops innovative technical solutions to a wide range of difficult process problems encountered in radiopharmaceutical manufacturing and support. Solutions are consistent with organization objectives.
  • Completes tasks independently after receiving general guidance on new projects or operational challenges.

Qualifications
  • 4-8 years of experience, preferred
  • Bachelor's, Masters, or PhD in Engineering or Chemistry is preferred.
  • Comfortable working in a nuclear environment
  • Ability to manage up to 25 pounds

What is expected of you and others at this level
  • Applies comprehensive knowledge and a thorough understanding of concepts, principles, and technical capabilities to perform varied tasks and projects.
  • May contribute to the development of policies and procedures.
  • Works on complex projects of large scope.
  • Develops technical solutions to a wide range of difficult problems.
  • Solutions are innovative and consistent with organization objectives.
  • Completes work; independently receives general guidance on new projects.
  • Work reviewed for purpose of meeting objectives.
  • May act as a mentor to less experienced colleagues.

Anticipated salary range: $80,900.00-$115,500.00
Bonus eligible: No
Benefits: Cardinal Health offers a wide variety of benefits and programs to support health and well-being.
  • Medical, dental and vision coverage
  • Paid time off plan
  • Health savings account (HSA)
  • 401k savings plan
  • Access to wages before pay day with myFlexPay
  • Flexible spending accounts (FSAs)
  • Short- and long-term disability coverage
  • Work-Life resources
  • Paid parental leave
  • Healthy lifestyle programs

Application window anticipated to close: 09/14/2026 *if interested in opportunity, please submit application as soon as possible.
The salary range listed is an estimate. Pay at Cardinal Health is determined by multiple factors including, but not limited to, a candidate's geographical location, relevant education, experience and skills and an evaluation of internal pay equity.
Candidates who are back-to-work, people with disabilities, without a college degree, and Veterans are encouraged to apply.
Cardinal Health supports an inclusive workplace that values diversity of thought, experience and background. We celebrate the power of our differences to create better solutions for our customers by ensuring employees can be their authentic selves each day. Cardinal Health is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, ancestry, age, physical or mental disability, sex, sexual orientation, gender identity/expression, pregnancy, veteran status, marital status, creed, status with regard to public assistance, genetic status or any other status protected by federal, state or local law.
To read and review this privacy notice click here

What Cardinal Health employees say

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About Cardinal Health

Sourced by ZipRecruiter

Cardinal Health Innovative Delivery Solutions With over 45 years of experience in helping hundreds of hospital and outpatient pharmacies, we provide access to best practice strategies and tactics to control costs, improve workflow and enhance safety. Cardinal Health Innovative Delivery Solutions is one of the largest employers of acute-care pharmacist in the United States. Cardinal Health is the employer of choice for pharmacists because we offer a variety of career opportunities in pharmacy leadership, clinical specialties, remote order entry, business management, medication therapy management and more.

Industry

Medical equipment and supplies manufacturing

Company size

10,000+ Employees

Headquarters location

Dublin, OH, US

Year founded

1971

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