Preclinical Biologist Jobs (NOW HIRING)

Job Title: Biologist

Location: Cambridge, MA

We are seeking an accomplished and highly motivated scientific leader in oncology and immuno‑oncology drug discovery to join our research organization. The successful candidate will have a strong background in cancer biology, target discovery and validation, and translational biomarker strategies, with demonstrated experience advancing innovative therapeutic concepts toward preclinical development.

This role combines strategic project leadership with hands‑on laboratory work. The position offers the opportunity to shape early discovery programs and collaborate extensively with internal and external partners.

Join the engine of Sanofi’s mission, where deep immunoscience meets bold, AI‑powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

We’re an R&D‑driven, AI‑powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

• Lead and drive oncology and immuno‑oncology discovery programs, from target identification through preclinical proof‑of‑concept.
• Contribute deep expertise in cancer biology, tumor immunology, and translational science, informing target selection, indication strategy, and experimental design.
• Support the discovery and preclinical development of innovative cancer therapeutics using diverse modalities, including small‑molecule inhibitors, targeted degraders, and biologics.
• Provide scientific leadership while remaining capable of hands‑on laboratory work, as needed, to directly support project teams.
• Manage and coordinate external collaborations with CROs, academic groups, and industry partners, ensuring scientific rigor, alignment with project goals, and timely delivery.

• PhD (or equivalent) in cancer biology, immunology, molecular biology, or a related life sciences discipline.
• Postdoctoral and industry experience in cancer biology and/or immuno‑oncology research.
• Strong track record in target identification and validation, mechanism‑of‑action studies, and biomarker discovery.
• Demonstrated experience supporting preclinical development of oncology therapeutics.
• Highly familiar with multiple therapeutic modalities, including small molecules, degraders (e.g., PROTACs), and biologics.
• Proven ability to lead scientific projects while contributing experimentally when required.
• Experience managing external research collaborations with CROs and academic or industry partners.
• Excellent scientific communication skills.
• Experience working with large scale data mining, or target discovery and translation to patient.

• Prior experience advancing programs from target‑ID to development candidate.
• Publications and/or patents in oncology or immuno‑oncology research.
• Experience working in a matrixed, cross‑functional pharmaceutical research environment.

• Bring the miracles of science to life alongside a supportive, future‑focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high‑quality healthcare, prevention and wellness programs and at least 14 weeks’ gender‑neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real‑world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting‑edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affiliation employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affiliation employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

US and Puerto Rico Residents Only

North America Applicants Only

Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com !

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The salary range for this position is:

$148,500.00 - $214,500.00

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK .