Job Summary:
Moffitt Cancer Center is a National Cancer Institute-designated Comprehensive Cancer Center based in Florida, dedicated to the prevention and cure of cancer. They are seeking a Postdoctoral Fellow in Bioinformatics to participate in research projects leveraging chemoproteomics and cancer genomics data to advance cancer biology and therapeutic discovery.
Responsibilities:
• Analyze and integrate high-dimensional chemoproteomics datasets with multi-omotic data (e.g., genomics, transcriptomics, proteomics) from public repositories such as DepMap and TCGA
• Develop, implement, and maintain robust computational pipelines in R and other programming languages (e.g., Python) for data processing, statistical analysis, and visualization
• Mine and interpret large-scale CRISPR screening datasets to identify novel cancer dependencies and therapeutic targets, utilizing resources such as DepMap and published CRISPR screens
• Collaborate with interdisciplinary teams of biologists, chemists, and clinicians to design and execute integrative studies, and contribute to the functional validation of computational predictions
• Present research findings at internal meetings and national/international conferences; publish results in high-impact journals
• Mentor junior researchers and contribute to grant writing and manuscript preparation
Qualifications:
Required:
• PhD in Bioinformatics, Computational Biology, Cancer Biology, Genomics, or a related field is required
• Demonstrated expertise in R and proficiency in other programming languages (e.g., Python)
• Experience working with and mining large public cancer genomics databases, such as DepMap and TCGA
• Proven track record in analyzing and integrating chemoproteomics and/or functional genomics datasets, especially CRISPR screening data
• Strong understanding of statistics and machine learning concepts as applied to biological data
• Excellent written and verbal communication skills, with a history of publishing in peer-reviewed journals
• Ability to work independently and collaboratively in a multidisciplinary research environment
Preferred:
• Experience with drug development and/or chemistry
• Familiarity with AI/ML approaches for biological data analysis
• Prior experience in cancer research or translational bioinformatics
Company:
Moffitt Cancer Center are contribute to the prevention and cure of cancer. Founded in 1984, the company is headquartered in Tampa, USA, with a team of 10001+ employees. The company is currently Late Stage.