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Roles & Responsibilities:
Postdoctoral Fellowship in Exposomics, Environmental Epidemiology, Environmental Medicine, Public Health, Biostatistics, Pediatrics and Medicine
A fully-funded PostDoc position is available with Dr. Alison Lee at the Icahn School of Medicine at Mount Sinai in NYC. Funding is guaranteed for 2 years with potential for further support. Dr. Lee's research leverages two NIH-funded ongoing pregnancy cohort studies investigating the impact of perinatal exposures (both chemical and non-chemical) on lung development and the programming of future respiratory disease in children, with a specific focus on epigenetic mechanisms including DNA methylation, non-coding microRNAs and long noncoding RNAs, and extracellular vesicle communications. Metabolomics and microbiome are also of interest. Further, these studies are part of the national ECHO (Environmental Influences on Children's Health Outcomes) Initiative and consider a range of additional outcomes, including growth and obesity, perinatal outcomes and neuropsychological development, allowing extension of epigenetic work to these outcomes. The successful postdoc will lead epidemiology and computational investigations of how these molecular mechanisms mediate the effects of high-resolution environmental exposures on human health.
Examples of active projects include:
1. Maternal trauma, circulating microRNA in extracellular vesicles, and programming of childhood respiratory outcomes
2. Prenatal PM2.5 and programming of respiratory outcomes: Placental biomarkers and effect modification by stress
3. ECHO consortium on perinatal programming of neurodevelopment
Team: The fellow will work closely with Dr. Lee and will be part of an interdisciplinary team of environmental epidemiologists, epigeneticists, and computational biologists dedicated to environmental health investigations.
Requirements:
Qualifications: Applicants should possess a Ph.D. in Environmental and/or Molecular Epidemiology, or alternatively, in other relevant disciplines, such as Statistics/Biostatistics, Computational Biology, Machine Learning, or Bioinformatics, with relevant previous work and interest in environmental health. Strong quantitative skills, practical experience working with complex epidemiology data, familiarity with the R statistical software packages and excellent oral communication and scientific writing are also necessary. Experience with high dimensional molecular data such as Illumina BeadChip methylation (450K, 850K or EPIC) and RNA-seq data is strongly preferred.
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About the Mount Sinai Health System:
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
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