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Phd Cryo Electron Microscopy Jobs in Bothell, WA

FHLB Des Moines

Research Scientist/Engr 4

Seattle, WA · On-site

$99.44 - $122.12/hr

Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics.**Purpose of the Research Project(s):**The goal of ...

New

Uw

Research Scientist/Engr 4

Seattle, WA · On-site

$122K/yr

Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics. Purpose of the Research Project(s): The goal of our ...

Uw

Research Scientist/Engineer 3

Seattle, WA

At least 4 years of hands-on experience in cryo-electron microscopy, including sample preparation, data collection, image processing, and structure building. Experience with cryoEM structure ...

All JobsPhd Cryo Electron Microscopy JobsPhd Cryo Electron Microscopy Jobs in Bothell, WA

Phd Cryo Electron Microscopy information

What is a PhD in cryo electron microscopy?

A PhD in Cryo-Electron Microscopy (Cryo-EM) is a doctoral program focused on using advanced electron microscopy techniques to study the structures of biological molecules at near-atomic resolution. Students in this field develop expertise in sample preparation, imaging, and data analysis to better understand the form and function of proteins, viruses, and other complex biomolecules. Graduates often contribute to scientific research in fields such as structural biology, biochemistry, and drug discovery.

What are the key skills and qualifications needed to thrive as a PhD cryo electron microscopy specialist?

To thrive as a PhD Cryo Electron Microscopy (Cryo-EM) specialist, you need a strong background in structural biology, biochemistry, and physics, typically supported by a doctoral degree in a related field. Expertise in operating advanced cryo-EM instruments, image processing software (such as RELION or CryoSPARC), and familiarity with data analysis pipelines is essential. Attention to detail, problem-solving ability, and effective collaboration skills help you excel when troubleshooting experiments and working within multidisciplinary teams. These competencies are crucial for generating high-quality structural data and advancing scientific discoveries in molecular biology.

What are some common challenges faced by PhD researchers specializing in cryo electron microscopy, and how can they be addressed?

PhD researchers in Cryo Electron Microscopy (Cryo-EM) often encounter challenges such as sample preparation issues, data collection bottlenecks, and interpreting complex datasets. Achieving optimal sample vitrification and minimizing beam-induced motion are technical hurdles that require patience and meticulous technique. Collaborating closely with experienced microscopists, leveraging advanced image processing software, and participating in specialized training workshops can greatly assist in overcoming these obstacles. Additionally, working in multidisciplinary teams fosters knowledge sharing and accelerates problem-solving, making it easier to advance high-impact structural biology projects.

What is the difference between Phd Cryo Electron Microscopy vs Phd Structural Biology?

AspectPhd Cryo Electron MicroscopyPhd Structural Biology
Required CredentialsPhD in relevant field, microscopy expertisePhD in biology, biochemistry, or related field
Work EnvironmentLaboratories with advanced microscopy equipmentResearch labs, academic institutions, biotech companies
Industry UsageUsed for high-resolution imaging of biomoleculesUsed for understanding biological structures and functions
Common Search/ComparisonOften compared for research focus and techniquesBroader biological context

While both roles require advanced degrees and involve biological research, Phd Cryo Electron Microscopy specializes in imaging techniques to visualize biomolecules at near-atomic resolution. Phd Structural Biology encompasses a broader understanding of biological structures, often integrating various methods including cryo-EM. The choice depends on whether the focus is on imaging technology or biological function analysis.

What job categories do people searching Phd Cryo Electron Microscopy jobs in Bothell, WA look for?

The top searched job categories for Phd Cryo Electron Microscopy jobs in Bothell, WA are:

Phd Cryo Electron Microscopy jobs near you
Infographic showing various Phd Cryo Electron Microscopy job openings in Bothell, WA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Research Scientist/Engr 4

FHLB Des Moines

Seattle, WA • On-site

$99.44 - $122.12/hr

Other

Posted yesterday

New

Job description

## Research Scientist/Engr 4Applylocations: Seattle, WAtime type: Full timeposted on: Posted 13 Days Agojob requisition id: REQ-0000129345**Job Description****Field of research:**Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics.**Purpose of the Research Project(s):**The goal of our research is to develop vaccines and therapeutics targeting human pathogens.**Duties and Responsibilities:**20% Structure-based and machine-learning immunogen design for protein subunit and mRNA vaccines based on viral surface glycoproteins (construct design, recombinant expression in mammalian cells, purification, and stability assays),20% Characterize protein antigenicity (binding assays using ELISAs, SPR and biolayer interferometry to evaluate binding kinetics and affinity of antibodies or designed proteins),15% Perform structural studies (high-throughput cryo-electron microscopy of subunit vaccines as well as of complexes between viral glycoproteins and monoclonal and polyclonal antibodies as well as X-ray crystallography), 10% Design and execution of virology assays,10% Analysis of the data to help determining the research strategy,10% Lead projects and/or major project tasks,10% Interactions with collaborators within our network and writing of manuscripts for publication5% Provide guidance and direction to project staff, students and postdocs**Requirements:**Master's Degree in Biochemistry or related field and four years 4 years of experience in related field like: Cryo-electron microscopy, virology assays (pseudotyped virus generation, cellular entry and neutralization assays), protein expression in mammalian cells and purificationEquivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.**Desire:**Expertise in protein and vaccine design, experience in high throughput automation using Beckman Biomek.**Compensation, Benefits and Position Details****Pay Range Minimum:**$99,444.00 annual**Pay Range Maximum:**$122,124.00 annual**Other Compensation:**-**Benefits:**For information about benefits for this position, visit https://www.washington.edu/jobs/benefits-for-uw-staff/**Shift:**First Shift (United States of America)**Temporary or Regular?**This is a regular position**FTE (Full-Time Equivalent):**100.00% #J-18808-Ljbffr

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