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Per Diem Infusion Rn Jobs in Columbia, SC (NOW HIRING)

Infusion Nurse RN

Sumter, SC · On-site

$40 - $70/hr

Registered Nurse (RN) - Infusion Nurse NurseCore is currently hiring Registered Nurses (RN) with Infusion experience for our Specialty Staffing division . NurseCore has a national footprint in Home ...

Registered Nurse (RN) - Infusion Nurse NurseCore is currently hiring Registered Nurses (RN) with Infusion experience for our Specialty Staffing division . NurseCore has a national footprint in Home ...

Infusion Nurse RN

Sumter, SC · On-site

$40 - $70/hr

Registered Nurse (RN) - Infusion Nurse NurseCore is currently hiring Registered Nurses (RN) with Infusion experience for our Specialty Staffing division . NurseCore has a national footprint in Home ...

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Per Diem Infusion Rn information

See Columbia, SC salary details

$10

$42

$76

How much do per diem infusion rn jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for per diem infusion rn in Columbia, SC is $42.52, according to ZipRecruiter salary data. Most workers in this role earn between $33.56 and $46.49 per hour, depending on experience, location, and employer.

What is a Per Diem Infusion RN?

A Per Diem Infusion RN is a registered nurse who specializes in administering intravenous (IV) therapies and medications, such as antibiotics, chemotherapy, or hydration fluids, on an as-needed, flexible, or part-time basis. 'Per diem' means 'per day,' indicating that these nurses do not have a set full-time schedule and may fill in shifts based on facility needs. They often work in hospitals, outpatient clinics, or patients’ homes, providing expert infusion care while enjoying flexible work arrangements. This role requires strong IV skills, attention to detail, and the ability to work independently.

What are the key skills and qualifications needed to thrive as a Per Diem Infusion RN?

To thrive as a Per Diem Infusion RN, you need a current RN license, strong IV insertion and infusion therapy skills, and experience with patient assessment in various clinical settings. Familiarity with infusion pumps, electronic health records (EHRs), and up-to-date certification in Basic Life Support (BLS) or Advanced Cardiovascular Life Support (ACLS) is typically required. Exceptional communication, adaptability, and the ability to work independently are vital soft skills for success in this flexible role. These skills and qualifications ensure safe, efficient care delivery and allow you to respond effectively to the diverse needs of patients across different assignments.

What are some common challenges faced by Per Diem Infusion RNs, and how can they be managed?

Per Diem Infusion RNs often encounter challenges such as quickly adapting to different clinical settings, managing varying patient loads, and staying updated on each facility's protocols. Flexibility and strong communication skills are key to overcoming these hurdles. Building a habit of thorough documentation and asking clarifying questions during each assignment can help ensure continuity of care and compliance. Networking with regular staff and maintaining up-to-date certifications also contribute to a smoother experience in this dynamic role.

What is the difference between Per Diem Infusion Rn vs Per Diem IV Therapy Nurse?

AspectPer Diem Infusion RnPer Diem IV Therapy Nurse
CertificationsRN license, infusion certificationRN license, infusion certification
Work EnvironmentHospitals, clinics, home careHospitals, clinics, home care
Job FocusAdministering various infusions, patient monitoringPrimarily IV therapy, infusion administration

Both roles require RN licensure and infusion certifications, working in similar healthcare settings. The main difference is that Per Diem Infusion Rns may handle a broader range of infusions beyond IV therapy, while Per Diem IV Therapy Nurses focus specifically on IV treatments. Both roles offer flexible, per diem schedules in healthcare environments.

What cities near Columbia, SC are hiring for Per Diem Infusion Rn jobs?

Cities near Columbia, SC with the most Per Diem Infusion Rn job openings:

Infographic showing various Per Diem Infusion Rn job openings in Columbia, SC as of August 2026, with employment types broken down into 3% As Needed, 58% Full Time, 16% Part Time, and 23% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $88,449 per year, or $42.5 per hour.

Home Infusion RN - Independent Contractor (Columbia, SC)

AmeriPharma

Columbia, SC

$60 - $70/hr

Contractor

Posted 4 days ago


Job description

About AmeriPharma

AmeriPharma is a rapidly growing healthcare company where you will have the opportunity to contribute to our joint success on a daily basis. We value new ideas, creativity, and productivity. We like people who are passionate about their roles and people who like to grow and change as the company evolves.


Job Summary

AmeriPharma is seeking a dedicated Registered Nurse (RN) with expertise in home infusion therapy to join our team. This role combines infusion therapy and patient education, providing both in-home care and valuable support to patients undergoing treatments such as TPN, IVIG, and IV biologics.

The RN will be responsible for providing telephone and in-person advice and education to patients. This role requires offering interventions, counseling, and support services that require significant nursing knowledge, judgment, and skills in psychological, biological, physical, and social sciences. Under the supervision of the Director of Nursing, the RN will make decisions based on their education, nursing experience, and clinical guidelines, ensuring optimal compliance and persistence in home infusion programs.


Schedule Details

  • Per Diem, Flexible Hours
  • Independent Contractor


Duties and Responsibilities

  • Conduct in-home infusion therapy visits with patients according to the plan of care.
  • Prepare clinical/nursing notes and document patient interventions in both clinical and non-clinical records consistently.
  • Act as a clinical resource, working collaboratively with other pharmacy departments.
  • Maintain knowledge of drug side effects and interactions.
  • Offer telephone and in-person patient education on therapy protocols, drug side effects, and home infusion procedures.
  • Ensure patients understand their therapy plans, medications, and the importance of adherence.
  • During initial and ongoing consultations, serve as a patient liaison between the patient, their family, and the pharmacy to ensure a seamless therapy process.
  • Perform comprehensive, initial, and periodic head-to-toe assessments for patients and initiate preventative and rehabilitative care.
  • Use health assessment data, and input from the agency team, the physician, the patient, and the family to determine patient needs.
  • Manage patient and family expectations regarding services, outcomes, and discharge goals.
  • Establish primary and secondary diagnoses based on patient assessment and home health care focus.
  • Develop care plans with skilled interventions, medical supplies, and necessary services to meet goals.
  • Regularly evaluate patient progress, in collaboration with team members, and revise care plans as needed.
  • Perform other duties as assigned.


Qualifications

  • Graduate of an accredited nursing school with a current RN state license.
  • 2+ years of experience in home infusion and infusion centers.
  • 2+ Experience with IV Immunoglobulins and IV Biologics. CRNI certification(Certified Registered Nurse Infusion) is preferred.
  • Experience with peripheral IV starts, infusion therapy, and phlebotomy for both adult and pediatric patients is preferred
  • Effective interpersonal, time management, and organizational skills.
  • Strong written and verbal communication skills.
  • Organizational ability to maintain consistently accurate records.
  • Ability to direct information to the appropriate healthcare provider.
  • Proficient in computer skills, including word processing, and efficient use of the internet and email.
  • Current CPR and BLS (Red Cross and AHA) certification, valid driver's license, reliable transportation, and automobile insurance.


AmeriPharma's Mission Statement

Our goal is to achieve superior clinical and economic outcomes while maintaining the utmost compassion and care for our patients. It is our joint and individual responsibility daily to demonstrate to outpatients, prescribers, colleagues, and others that We Care!


Physical Requirements

The physical requirements for this role includes constant active work that primarily involves sitting/standing. May frequently move about inside and outside the work area (patient's home) to access medical equipment. Must be physically able to operate a computer and other office productivity machinery (i.e., a laptop, phone, etc.). Must be able to constantly communicate with patients and team including via telephone and texting. Must be able to lift up to 20 pounds at times. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.


EEO Statement

The above statements are intended to describe the work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, duties and skills required. The duties and responsibilities of this position are subject to change and other duties may be assigned or removed at any time. AmeriPharma values diversity in its workforce and is proud to be an AAP/EEO employer. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, age, protected veteran status, or on the basis of disability or any other legally protected class.