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Organoids Postdoc Jobs in Tennessee (NOW HIRING)

Organoids Postdoc information

What is an organoids postdoc?

Organoids Postdocs are scientists who have completed their doctoral studies and are engaged in postdoctoral research focused on organoid technology. Organoids are 3D, miniaturized, and simplified versions of organs grown in vitro from stem cells, used to model organ development, physiology, and disease. These postdocs typically work in academic or industry labs, contributing to advancements in disease modeling, drug discovery, and regenerative medicine. Their work combines cell biology, tissue engineering, and molecular techniques to develop and analyze organoid systems.

What are the key skills and qualifications needed to thrive as an organoids postdoc?

To thrive as an Organoids Postdoc, you need a PhD in a relevant field (such as biology or biomedical sciences), along with expertise in stem cell biology, tissue culture, and molecular biology techniques. Experience with advanced imaging systems, organoid culture platforms, and possibly single-cell sequencing technologies is highly valuable. Strong problem-solving skills, scientific curiosity, and effective collaboration are crucial soft skills for driving innovative research and working within interdisciplinary teams. These qualifications and skills enable high-quality, reproducible research and contribute to advances in organoid-based disease modeling and drug discovery.

What are some common challenges faced by organoids postdocs when establishing new organoid models in the lab?

Organoids Postdocs often encounter challenges such as optimizing protocols for specific tissue types, ensuring reproducibility across experiments, and managing contamination risks. Establishing new organoid models requires careful selection of cell sources, fine-tuning of culture conditions, and troubleshooting issues like poor growth or differentiation. Collaborating with other team members, such as bioinformaticians and imaging specialists, is essential for validating models and interpreting complex data. Patience and adaptability are key, as developing robust organoid systems can take significant time and iterative adjustments.

What job categories do people searching Organoids Postdoc jobs in Tennessee look for?

The top searched job categories for Organoids Postdoc jobs in Tennessee are:

Postdoctoral Research Associate - Developmental Neurobiology

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Re-posted yesterday


St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

43rd of 1,061 rated hospitals


Job description

A postdoctoral position is available in the laboratory of Dr. Young-Goo Han in the Department of Developmental Neurobiology/Neurobiology and Brain Tumor Program at St. Jude Children's Research Hospital. The Han laboratory studies the biology of primary cilia and how cilia-dependent signaling regulates cell behavior in normal development and disease, with particular emphasis on brain development, brain tumors, neurodevelopmental disorders, and neurodegenerative diseases.
The Han laboratory has made important contributions to understanding the roles of primary cilia and Hedgehog signaling in neural stem cell formation, cerebellar development, medulloblastoma, neocortical growth and folding, and cilia-dependent regulation of translation and the cell cycle. Applicants who are interested in fundamental mechanisms by which primary cilia or mitochondria control cellular homeostasis and signaling are encouraged to apply.
We use a broad range of approaches, including human pluripotent stem cells, brain organoids, genome editing, high-resolution imaging, single-cell sequencing, spatial transcriptomics, epigenomics, and proteomics, as well as a unique mouse model in which neural progenitors acquire key features of human neural progenitors, driving expansion and folding of the normally small, smooth mouse cortex.
Research areas may include:
  • Primary cilia and compartmentalized signaling
  • Cell and molecular mechanisms of cilia function
  • Mitochondrial homeostasis
  • Brain development and neural progenitor biology
  • Brain tumor biology
  • Neurodevelopmental and neurodegenerative disorders

QualificationsApplicants should have a Ph.D., M.D., or equivalent degree and a strong background in cell biology, molecular biology, developmental biology, neuroscience, cancer biology, neurodegeneration, or a related field. Experience in one or more of the following areas is desirable: primary cilia biology, mitochondrial homeostasis, mouse genetics, imaging, biochemistry, genomics, stem/progenitor cell biology, or disease models. Highly motivated candidates with strong communication skills and a record of scientific productivity are encouraged to apply.
EnvironmentSt. Jude provides an outstanding and highly collaborative research environment with exceptional core facilities and strong support for postdoctoral training and career development. The Han laboratory offers opportunities to pursue mechanistic and conceptually innovative projects at the interface of cell biology, development, and disease.
To applyPlease send:
a cover letter describing research interests and career goals, a curriculum vitae, and contact information for three references
to:
Young-Goo Han, Ph.D.St. Jude Children's Research Hospitalyoung-goo.han@stjude.org
St. Jude is an Equal Opportunity Employer
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