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Ngs Engineer Jobs (NOW HIRING)

Prime Medicine

Informatics Engineer

Cambridge, MA · On-site

Your engineering judgment about what to build and how to build it will shape how Prime Medicine ... Design and build the data platform connecting NGS instruments, laboratory informatics systems ...

Natera

Senior Lab Automation Engineer

Austin, TX · On-site

$103K - $135K/yr

Background in NGS laboratories is a plus, as is background in clinical laboratories. * Experience ... Experience in programming and operating liquid handlers. (Tecan, Hamilton, etc) * Experience ...

Prime Medicine, Inc.

Your engineering judgment about what to build and how to build it will shape how Prime Medicine ... Design and build the data platform connecting NGS instruments, laboratory informatics systems ...

F. Hoffmann-La Roche AG

$127K - $236K/yr

The Opportunity As a Principal Systems Engineer II within our System Development & Integration team ... Deep hands-on background in Next-Generation Sequencing (NGS) platforms, molecular diagnostics, and ...

Roche

Principle Systems Engineer II

Santa Clara, CA · Hybrid

$127K - $236K/yr

The Opportunity As a Principal Systems Engineer II within our System Development & Integration team ... Deep hands-on background in Next-Generation Sequencing (NGS) platforms, molecular diagnostics, and ...

Natera

Software Test Engineer

Boulder, CO · On-site

Familiarity with NGS workflows and/or clinical laboratory operations (CLIA, CAP, or equivalent ... Experience working cross-functionally with engineering, bioinformatics, and quality teams

GenomOncology

Senior Application Engineer

Cleveland, OH · On-site

As a Senior Application Engineer, you will bridge the gap between our clients and our product ... Experience with genomics or NGS testing is valuable but not required; candidates who learn quickly ...

New

SimIS Inc.

Senior Systems Engineer (S)

Dahlgren, VA · On-site

$106K - $145K/yr

Apply knowledge of simulation systems including NGS, OASIS, JSAF, and tactical training ... Eight (8) years of systems engineering experience with three (3) years in leadership roles

SimIS Inc.

Senior Systems Engineer (S)

Dahlgren, VA · On-site

$106K - $145K/yr

Apply knowledge of simulation systems including NGS, OASIS, JSAF, and tactical training ... Eight (8) years of systems engineering experience with three (3) years in leadership roles

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How much do ngs engineer jobs pay per year?

As of Sep 15, 2026, the average yearly pay for ngs engineer in the United States is $106,386.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,000.00 and $132,500.00 per year, depending on experience, location, and employer.

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Infographic showing various Ngs Engineer job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 2% Part Time, and 6% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $106,386 per year, or $51.1 per hour.

Informatics Engineer

Cambridge, MA • On-site

Scorpion Therapeutics
51 - 200 employees
Learn more about Scorpion Therapeuticsexternal

Other

Posted 16 days ago

Job description

About The Role
  • We’re hiring an Informatics Engineer to build the scientific data and computing platform that powers Prime Medicine’s gene editing programs.
What You’ll Do
  • Design and build the data platform connecting NGS instruments, Benchling, and AWS compute (automated ingestion, provenance tracking, scalable storage, observability).
  • Build production-grade APIs, SDKs, and internal tools for genomic data and analytics.
  • Build an orchestration layer for automated, event-triggered execution of scientific pipelines; own how they run, scale, and integrate.
  • Ship AI-powered and agentic capabilities (RAG over internal scientific data, human-in-the-loop workflows, internal copilots).
  • Build integrations across ELNs, LIMS, instrument software, and cloud compute.
  • Translate scientific requirements into reliable, maintainable software; move prototypes into production.
  • Partner with computational biologists, lab scientists, and cloud-support to improve performance, cost, and reliability.
Requirements
  • 5+ years (3+ with MS/PhD) engineering experience in production environments.
  • Strong Python.
  • Production AWS: event-driven, cloud-native (AWS Lambda, EventBridge or equivalent) and Infrastructure as Code (Terraform or CDK).
  • Docker/containerization; Git; CI/CD; testing in DEV/TEST.
  • Track record building integrations/automations; experience in life-science with scientific/regulated data.
Nice to have
  • NGS expertise; workflow orchestration (Nextflow/Seqera); Benchling/ELN/LIMS.
  • AI/LLM tooling (LangChain, LangGraph, RAG, MCPs); gene editing familiarity (CRISPR/base/prime).
  • GxP/21 CFR Part 11; internal app/data viz tools; relational DBs (PostgreSQL/MSSQL).
Interview process
  • Recruiter call, hiring manager interview, and panel; includes a Python coding exercise.
Logistics
  • Hybrid (Cambridge, MA). No visa sponsorship; US work authorization required.
  • Competitive base salary, equity, and standard benefits; eligible for annual short- and long-term incentives.
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