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Next Generation Sequencing Jobs in Worcester, MA

BostonGene

Scientist/Sr. Scientist - NGS

Waltham, MA · On-site

Position Overview BostonGene is seeking a bench Scientist to join our R&D next-generation sequencing (NGS) team in our laboratory located in Waltham, MA. This candidate will support assay development ...

Aquyre Biosciences, Inc.

Production Technician

Weston, MA · On-site

$18.50 - $23.25/hr

Tissue and biopsy assessment is critical for the proceduralists doing the biopsies, for the patients who need immediate information and Next Generation Sequencing that requires enough live cancer ...

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Next Generation Sequencing information

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$28.4K

$66.1K

$115.7K

How much do next generation sequencing jobs pay per year?

As of Aug 26, 2026, the average yearly pay for next generation sequencing in Worcester, MA is $66,125.00, according to ZipRecruiter salary data. Most workers in this role earn between $38,900.00 and $82,800.00 per year, depending on experience, location, and employer.

What is next generation sequencing?

A Next Generation Sequencing (NGS) job involves working with advanced DNA and RNA sequencing technologies to analyze genetic material. Professionals in this field may design experiments, prepare biological samples, operate sequencing instruments, and interpret genomic data. Roles can vary from research scientists and bioinformaticians to lab technicians and data analysts. NGS is widely used in medicine, agriculture, and biotechnology for applications such as disease research, personalized medicine, and evolutionary studies. Strong skills in molecular biology, computational analysis, and data interpretation are typically required.

What does someone working in next generation sequencing do?

Professionals in Next Generation Sequencing typically spend their days preparing and processing biological samples, operating sequencing instruments, and analyzing genomic data. They are responsible for troubleshooting technical issues, maintaining laboratory equipment, and ensuring quality control throughout the sequencing workflow. Collaboration with cross-functional teams—such as bioinformaticians, clinicians, and research scientists—is common to interpret sequencing results and contribute to project goals. This role also involves detailed record-keeping and adherence to regulatory or laboratory standards, making organization and communication important aspects of the job.

What are the key skills and qualifications needed to thrive in next generation sequencing?

To excel in a Next Generation Sequencing (NGS) role, you need a strong background in molecular biology, genomics, and data analysis, often supported by a degree in a life science field. Proficiency with NGS platforms (such as Illumina or Oxford Nanopore), laboratory automation tools, and bioinformatics software is highly valued, alongside relevant certifications in genomics or molecular diagnostics. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills set successful professionals apart. These competencies ensure high-quality sequencing results, efficient workflow, and productive collaboration in fast-paced research or clinical environments.

What are popular job titles related to Next Generation Sequencing jobs in Worcester, MA?

For Next Generation Sequencing jobs in Worcester, MA, the most frequently searched job titles are:

What job categories do people searching Next Generation Sequencing jobs in Worcester, MA look for?

The top searched job categories for Next Generation Sequencing jobs in Worcester, MA are:

What cities near Worcester, MA are hiring for Next Generation Sequencing jobs?

Cities near Worcester, MA with the most Next Generation Sequencing job openings:

Next Generation Sequencing jobs near you
Infographic showing various Next Generation Sequencing job openings in Worcester, MA as of August 2026, with employment types broken down into 50% Full Time, 21% Part Time, and 29% Contract. Highlights an 88% In-person, and 12% Remote job distribution, with an average salary of $66,125 per year, or $31.8 per hour.

Senior Scientist, Antibody Repertoire Sequencing & Discovery

AbbVie

Worcester, MA • On-site

$109K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 12 days ago

AbbVie rating

8.7

Company rating: 8.7 out of 10

Based on 102 frontline employees who took The Breakroom Quiz

14th of 86 rated pharmaceutical

Job description

Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
The Biotherapeutics and Genetics Medicine department within Discovery Research is seeking a highly motivated Senior Scientist to join the Molecular Core team at AbbVie Bioresearch Center (ABC). The ABC site in Worcester, MA, offers a unique setting where Biotherapeutics discovery, development and manufacturing coexist in one location. The Molecular Core partners with multidisciplinary groups across AbbVie focused on developing therapies for Immunology, Neurology and Oncology diseases. We utilize innovative approaches for antibody discovery including in vivo technologies, custom immunization strategies, advanced multiplex screening assays and best-in-class automation platforms to enable successful antibody discovery against complex targets.
As a member of the in vivo antibody discovery group, you will be responsible for optimizing and expanding antibody repertoire sequencing capabilities in antibody discovery, as well as developing innovative methods to help maintain AbbVie's industry-leading standards. The successful candidate will generate original technical ideas and research strategies for antibody repertoire sequencing (RepSeq) and analysis. They will have technical expertise in generating and applying RepSeq data to therapeutic antibody discovery including computational proficiency enabling highly effective collaboration with computational scientists. This is an exciting opportunity to help drive antibody discovery programs within a multidisciplinary research group in a dynamic, fast-paced environment.
Responsibilities:
  • Act as scientific and technical expert in antibody repertoire sequencing (RepSeq/AIRR-Seq/BCR-Seq) for therapeutic antibody discovery and hit expansion - Bulk sequencing, 10X, and other commercial and proprietary platforms.
  • Collaborate with computational scientists to optimize repertoire analysis and open new avenues for antibody discovery through repertoire guided machine learning and generative design
  • Generate, document, and archive repertoire data with appropriate context and metadata to support broader team access and future utilization.
  • Analyze and interpret results, placing data in proper scientific context through review of relevant literature, and present findings at team meetings.
  • Regularly present data, communicate effectively, and coordinate work within a highly matrixed project team environment.
  • Demonstrate scientific excellence through dedication to multiple projects in a fast-paced, multidisciplinary environment.
  • Exhibit a can-do attitude and strong interpersonal and communication skills when working across multiple functional teams.

Qualifications
  • BS, MS, or PhD in immunology, molecular biology, biochemistry, bioinformatics or a related field with typically 0-4+ (PhD), 8-10+ (MS), or 10-12+ (BS) years of relevant experience
  • Extensive scientific expertise in immunoglobulin genetics and antibody biology; specifically, the candidate should be well versed in antibody diversity generation (germline genes / V(D)J recombination / somatic hypermutation), affinity maturation, and B cell biology.
  • Extensive technical expertise in the isolation and molecular biology of antibody variable region genes for Next-generation Sequencing (NGS) and the capture of RepSeq/AIRR-Seq/BCR-Seq) data; both for single-chain and paired heavy- and light-chain recovery
  • Understanding of NGS technologies and platforms - Illumina (NextSeq, MiSeq) and PacBio
  • Understanding and proficiency in molecular biology techniques (e.g. PCR, primer design, molecular cloning, Gibson Assembly, plasmid design)
  • Ability to improve and streamline existing processes
  • Strong attention to quality and details when exercising organizational, documentation and communication skills
  • Proven flexibility to deal with changing timelines and shifting work priorities
  • Competency with software programs, including antibody analysis (PipeBio), DNA analysis (Geneious, Sequencher) and MS Office (Excel, PowerPoint, Word)
  • Fluency in computational science and familiarity with the application of predictive AI/ML tools and protein language models (PLMs) for antibody discovery

Desirable:
  • Experience in non-human and non-murine immunogenetics
  • Prior experience with bioinformatics and computational analysis of large DNA and protein data sets is highly desired
  • Experience with repertoire sequencing from in vitro antibody discovery libraries
  • Experience with mammalian cell culture, aseptic technique, and transient transfection
  • Experience in immunoassays using techniques like ELISA and flow cytometry

Position will be filled at level commensurate with extent of education, experience, and accomplishment - Senior Scientist I or Senior Scientist II
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive program.
  • This job may be eligible to participate in our long-term incentive program.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html

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About AbbVie

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AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

North Chicago, IL, US

Year founded

2013

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