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National Lab Postdoc Jobs in Texas (NOW HIRING)

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National Lab Postdoc information

What is a National Lab postdoc?

A National Lab Postdoc is a researcher who has recently completed their Ph.D. and is undertaking postdoctoral research at a U.S. Department of Energy (DOE) National Laboratory or similar federally funded research facility. These positions are typically temporary and provide early-career scientists with opportunities to deepen their expertise, work on cutting-edge projects, and collaborate with leading experts in the field. National Lab Postdocs often work on interdisciplinary teams and have access to state-of-the-art facilities and resources, making these roles highly sought after for those pursuing careers in research or academia.

What are the key skills and qualifications needed to thrive as a National Lab postdoc?

To thrive as a National Lab Postdoc, you need a Ph.D. in a relevant scientific or engineering field, a strong research background, and expertise in experimental or computational methods. Familiarity with specialized laboratory equipment, data analysis software, and scientific publishing platforms is typically required. Critical thinking, collaboration, and effective communication are essential soft skills for advancing research projects and sharing results. These skills and qualifications are vital for driving innovation, meeting research goals, and contributing to high-impact scientific discoveries in a collaborative environment.

What are some common challenges faced by National Lab postdocs, and how can they be addressed?

National Lab Postdocs often encounter challenges such as balancing independent research with collaborative projects, adapting to the unique mission-driven environment of national laboratories, and managing time between research, publishing, and networking. To address these, it's helpful to set clear project goals with mentors, actively seek interdisciplinary collaboration opportunities, and participate in lab-wide seminars or workshops. Many labs also offer mentorship programs and professional development resources to support postdocs in overcoming these challenges and advancing their careers.

What is the difference between National Lab Postdoc vs Research Scientist?

AspectNational Lab PostdocResearch Scientist
Required credentialsPhD in relevant fieldPhD or equivalent experience
Work environmentResearch-focused, academic setting within national labsResearch and development in industry or academia
Employer and industry usagePrimarily government-funded national labsPrivate companies, universities, or government agencies
Common search intentPostdoctoral research opportunities at national labsResearch roles in industry or academia

National Lab Postdocs are typically early-career researchers with a PhD working in government-funded labs, focusing on fundamental research. Research Scientists often have similar credentials but work in industry or academia, with more independence and potential for career advancement. Both roles involve research but differ mainly in employer and work environment.

National Lab Postdoc jobs near you
Infographic showing various National Lab Postdoc job openings in Texas as of August 2026, with employment types broken down into 1% As Needed, 75% Full Time, 19% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution.

Postdoctoral Researcher - Center for Cellular Therapy & Cancer Immunology - Choi Lab

Dallas, TX • On-site

University Of Texas Southwestern Medical Cent (The
Hospitals • 10K+ employees
Learn more about University Of Texas Southwestern Medical Cent (Theexternal

Full-time

Medical, Retirement, PTO

Posted 10 days ago

UT Southwestern rating

7.9

Company rating: 7.9 out of 10

Based on 152 frontline employees who took The Breakroom Quiz

Job description

Position Overview

The Choi Laboratory is seeking a highly motivated and collaborative postdoctoral researcher to help develop the next generation of cancer immunotherapies. Our research integrates cancer immunology, T-cell and protein engineering, and translational science to uncover mechanisms of immune regulation and convert those discoveries into rationally designed therapies.

The successful candidate will join the Center for Cellular Therapies and Cancer Immunology and work alongside basic scientists, translational researchers, and clinicians with expertise in immunology, cancer biology, molecular engineering, and therapeutic development. Projects are designed to progress from mechanistic discovery through preclinical development, providing exposure to programs moving toward first-in-human studies. This position is particularly well suited for researchers seeking rigorous scientific training and preparation for careers in academia, biotechnology, or translational medicine.

Research Focus

The successful candidate will investigate and engineer immune responses in cancer, with particular emphasis on:

  • T-cell engineering
  • Cancer immunology and immunotherapy
  • Protein and cell engineering for next-generation immunotherapies

Why Join the Choi Laboratory at UT Southwestern?

UT Southwestern Medical Center is an internationally recognized academic medical center where scientists and clinicians work together to translate discovery into better treatments. Through the Choi Laboratory's affiliations with the Center for Cellular Therapies and Cancer Immunology and the Harold C. Simmons Comprehensive Cancer Center, postdoctoral researchers have access to multidisciplinary expertise, advanced shared core facilities, extensive institutional research support, and opportunities to connect laboratory discoveries with unmet clinical needs.

The Harold C. Simmons Comprehensive Cancer Center is an NCI-designated Comprehensive Cancer Center recognized for excellence across basic, clinical, prevention, and population-based cancer research. This highly collaborative environment allows postdoctoral researchers to engage with scientists and clinicians across traditional disciplinary boundaries while developing the technical, scientific, and professional skills needed for their next career stage.

Postdoctoral researchers receive a competitive salary and comprehensive benefits, individualized mentoring, and access to institutional career-development resources. Located in Dallas, UT Southwestern combines the resources and scientific community of a major academic medical center with the professional and cultural opportunities of one of the country's largest and most diverse metropolitan areas.

Candidates must hold a recent Ph.D. in Immunotherapy, Molecular Biology, or a related field. Experience in cellular and molecular biology techniques. Candidates must also have experience with flow cytometry and immunological techniques leading to publication in peer-reviewed journals is recommended.

Preferred Qualifications include experience with mouse models, familiarity with next-generation sequencing analysis, a background in T cell biology or cancer immunology, and programming skills (R, Python) for data analysis.

Please read recent manuscripts published in the last two years.

Learn More

Explore the Choi Laboratory's research, publications, and ongoing programs:

  • Choi Laboratory website: Choi (Jaehyuk) Lab | UT Southwestern, Dallas, Texas

  • Laboratory research overview: https://www.youtube.com/watch?v=ZMnKZ0bko0U

  • Dr. Jaehyuk Choi Influuent: Jaehyuk Choi - University of Texas Southwestern Medical Center

Applicants should apply at https://jobs.utsouthwestern.edu/Search for Job # 956910

Information on our postdoctoral training program, benefits, and a virtual tour can be found at htt;s://www.utsouthwestern.edu/postdocs

UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis ofrace, color, religion, national origin, sex,sexual orientation, gender identity, gender expression,age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visithttps://www.utsouthwestern.edu/employees/hr-resources/

Benefits
    UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
    • PPO medical plan, available day one at no cost for full-time employee-only coverage
    • 100% coverage for preventive healthcare - no copay
    • Paid Time Off, available day one
    • Retirement Programs through the Teacher Retirement System of Texas (TRS)
    • Paid Parental Leave Benefit
    • Wellness programs
    • Tuition Reimbursement
    • Public Service Loan Forgiveness (PSLF) Qualified Employer
    • Learn more about these and other UTSW employee benefits!

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