1

Middleware Infrastructure Engineer Jobs in Indiana

Security Analyst Sr

Indianapolis, IN · On-site

$97K - $169K/yr

Represents infrastructure security support in significant projects and performs the most complex ... middleware, disaster recovery, collaboration technologies, hardware/software support or other ...

Security Analyst Sr

Indianapolis, IN · On-site

$97K - $169K/yr

Represents infrastructure security support in significant projects and performs the most complex ... middleware, disaster recovery, collaboration technologies, hardware/software support or other ...

Security Analyst Sr

Indianapolis, IN · On-site

$97K - $169K/yr

Represents infrastructure security support in significant projects and performs the most complex ... middleware, disaster recovery, collaboration technologies, hardware/software support or other ...

Showing results 41-51

Middleware Infrastructure Engineer information

What does a middleware infrastructure engineer do?

A Middleware Infrastructure Engineer is responsible for designing, implementing, and maintaining the software that connects different applications or services within an organization. They ensure that middleware platforms, such as application servers, message brokers, and integration tools, are properly configured, secured, and optimized for performance. These engineers work closely with development, operations, and security teams to support business-critical applications and ensure seamless data flow and communication between systems.

What are the key skills and qualifications needed to thrive as a middleware infrastructure engineer?

To thrive as a Middleware Infrastructure Engineer, you need a strong background in computer science, expertise in middleware platforms (such as WebLogic, IBM WebSphere, or Apache Tomcat), and experience with system integration. Familiarity with scripting languages, automation tools, cloud services, and relevant certifications like Red Hat Certified Specialist or AWS certifications are commonly expected. Strong problem-solving skills, effective communication, and the ability to work collaboratively in cross-functional teams help you stand out in this role. These skills ensure reliable middleware performance, efficient troubleshooting, and seamless integration of applications across complex IT environments.

What are some common challenges faced by middleware infrastructure engineers in supporting enterprise applications?

Middleware Infrastructure Engineers often encounter challenges such as ensuring high availability and performance of middleware platforms, troubleshooting complex integration issues, and managing upgrades with minimal downtime. They must work closely with development, operations, and security teams to implement best practices and resolve incidents quickly. Staying current with evolving technologies and maintaining consistent configurations across heterogeneous environments are also key demands of the role.

What is the difference between Middleware Infrastructure Engineer vs Network Engineer?

AspectMiddleware Infrastructure EngineerNetwork Engineer
Required CredentialsBachelor's in CS or related, certifications like AWS, Cisco (CCNA)Bachelor's in CS, EE, certifications like Cisco CCNA, CompTIA Network+
Work EnvironmentData centers, cloud platforms, enterprise serversNetwork operations centers, data centers, enterprise networks
Employer & Industry UsageIT companies, cloud providers, large enterprisesTelecom, IT, large enterprises, service providers
Common Search & ComparisonYesYes

The Middleware Infrastructure Engineer focuses on designing, deploying, and maintaining middleware systems that enable communication between applications, often working with cloud platforms and enterprise servers. In contrast, the Network Engineer specializes in managing and troubleshooting network infrastructure, including routers, switches, and firewalls. Both roles require similar certifications and work environments but differ in their core responsibilities and technical focus areas.

What cities in Indiana are hiring for Middleware Infrastructure Engineer jobs?

Cities in Indiana with the most Middleware Infrastructure Engineer job openings:

Technical Lead Architect, Global Patient Safety

Indianapolis, IN • On-site

Eli Lilly and Company
Pharmaceutical Product Wholesalers • 10K+ employees

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 20 days ago


Eli Lilly and Company rating

8.9

Company rating: 8.9 out of 10

Based on 64 frontline employees who took The Breakroom Quiz


Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work-but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.


The Technical Lead Architect is a senior technology leader, responsible for technical architecture, design, development and integration of a broad range of advanced technology solutions for the Patient Safety organization. This role acts as the primary technical authority across Safety systems and their integrations with adjacent platforms (e.g., Quality, Regulatory, Clinical, and Data platforms), ensuring solutions are scalable, compliant, and aligned with business and regulatory requirements. Partnering tightly with Software Product Engineering, Cyber Security, and Infrastructure & Digital Core, the lead architect drives shared strategies and architectures, while researching and applying emerging technology-including AI and agentic engineering-to advance capability and drive adoption.

Key Responsibilities

  • Own the technical direction of complex initiatives across Global Patient Safety, shaping modern, resilient, secure solutions.
  • Lead data and solution integration across the ecosystem, ensuring reliable, performant connectivity between Global Patient Safety systems, data products, and other platforms and systems.
  • Develop and maintain architecture roadmaps, technical standards, and reference architecture for the Patient Safety technology landscape.
  • Research and apply emerging technology-AI/ML, agentic workflows, intelligent automation-driving adoption.
  • Champion modernization and resilience, reducing technical debt and improving fault tolerance, observability, and recoverability.
  • Embed secure and AI-assisted engineering (code generation, automated testing, anomaly detection, threat-aware design) to accelerate delivery and improve operational quality.
  • Serve as a recognized expert, defining integration patterns and engineering standards adopted across Global Patient Safety teams.
  • Elevate technical colleagues by sharing data, integration, and security knowledge to broaden team impact.
  • Assume the role of Technical System Owner for GPS systems, accountable for the technical lifecycle, validated state and compliance.
  • Serve as the technical lead across multiple concurrent projects, providing hands-on guidance to developers, configuration analysts and integration and support teams.
  • Partner with Software Product Engineering, Cyber Security, and Infrastructure & Digital Core to drive aligned strategies, shared standards, and secure-by-design architectures.

Basic Qualifications

  • Bachelor's degree in Computer Science, Software Engineering, Information Technology, or a relatedfield.
  • 8+ years of experience in IT architecture, systems integration, or technical lead roles, of which at least 5+ years of software/systems engineering experience delivering complex, enterprise-scale solutions for Patient Safety Organization, with clear technical ownership.

Additional Qualifications

  • Strong communicationand cross-functional influencing skills.
  • Experience in Good Pharmacovigilance Practices (GVP), Good Clinical Practice (GCP), or a regulated (GxP) environment within pharmaceutical, biotech, or healthcare.
  • Hands-on experience developing and integrating AI/agentic capabilities into operational systems.
  • Strong understanding of system integration patterns (APIs, middleware, ETL, data mapping) and enterprise architecture principles.
  • Hands-on experience with Safety systems (e.g., Veeva Safety, Oracle Argus).
  • Experience across integrations, APIs, event-driven architecture, and cloud platforms (Azure, AWS, or GCP).

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.


Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.


Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).


Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is

$126,000 - $224,400

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly


What Eli Lilly and Company employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Eli Lilly logo

About Eli Lilly

Sourced by ZipRecruiter

Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.

Industry

Pharmaceutical product wholesalers

Company size

10,000+ Employees

Headquarters location

Indianapolis, IN, US

Year founded

1876