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Metabolomics Jobs in California (NOW HIRING)

Genentech

Principal Scientist

South San Francisco, CA · On-site

$143K - $265K/yr

The Opportunity SE7 As a Principal Scientist in Small Molecule Biomarkers (Metabolomics & Lipidomics) within our Drug Metabolism and Pharmacokinetics (DMPK) team, you will play a key role in ...

Genentech

Principal Scientist

San Francisco, CA · On-site

$143.20 - $265.90/hr

The Position The Opportunity SE7 As a Principal Scientist in Small Molecule Biomarkers (Metabolomics & Lipidomics) within our Drug Metabolism and Pharmacokinetics (DMPK) team, you will play a key ...

Relentless Health, Inc.

Scientist I/II

Menlo Park, CA · On-site

$120K - $160K/yr

Proficiency in untargeted and targeted metabolomics and lipidomics data processing, statistical analysis and data interpretation is essential. * Proficiency using Python based analysis tools is ...

Relentless Health, Inc.

Scientist I/II

Menlo Park, CA · On-site

$120K - $160K/yr

Proficiency in untargeted and targeted metabolomics and lipidomics data processing, statistical analysis and data interpretation is essential. * Proficiency using Python based analysis tools is ...

Genentech

Principal Scientist

South San Francisco, CA · On-site

$143.20 - $265.90/hr

The Position The Opportunity SE7 As a Principal Scientist in Small Molecule Biomarkers (Metabolomics & Lipidomics) within our Drug Metabolism and Pharmacokinetics (DMPK) team, you will play a key ...

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Metabolomics information

What is a metabolomics job?

A Metabolomics job involves studying small molecules (metabolites) in biological systems to understand metabolic processes, biomarkers, and disease mechanisms. Professionals in this field use advanced analytical techniques like mass spectrometry and NMR spectroscopy to identify and quantify metabolites. They work in research institutions, pharmaceuticals, healthcare, and biotechnology to develop diagnostics, therapies, and personalized medicine. Strong knowledge of chemistry, biology, and data analysis is essential for this role.

What are the key skills and qualifications needed to thrive in a metabolomics position?

To thrive in a Metabolomics role, you need a solid background in biochemistry or molecular biology, experience with analytical techniques like mass spectrometry or NMR, and typically a graduate degree in a relevant field. Proficiency with laboratory instrumentation, bioinformatics tools, data analysis software such as MetaboAnalyst, and familiarity with quality control standards are highly valued. Attention to detail, problem-solving skills, effective communication, and the ability to work collaboratively in multidisciplinary teams are crucial soft skills. These skills ensure accurate data generation, meaningful biological interpretation, and effective contribution to research or clinical projects.

What does a typical workday look like for someone in a metabolomics position?

A typical workday in Metabolomics often involves preparing biological samples, running analyses on instruments like LC-MS or NMR, and processing large data sets using specialized software. You may collaborate with colleagues in bioinformatics, biology, or clinical teams to interpret results and troubleshoot experimental issues. Throughout the week, there are often meetings to discuss findings, plan experiments, or coordinate with external partners such as core facilities or research collaborators. This dynamic environment provides opportunities to contribute to scientific discovery, advance technical expertise, and take on increasing responsibility with experience.

What are the most commonly searched types of Metabolomics jobs in California?

The most popular types of Metabolomics jobs in California are:

What are popular job titles related to Metabolomics jobs in California?

For Metabolomics jobs in California, the most frequently searched job titles are:

What job categories do people searching Metabolomics jobs in California look for?

The top searched job categories for Metabolomics jobs in California are:

What cities in California are hiring for Metabolomics jobs?

Cities in California with the most Metabolomics job openings:

Metabolomics jobs near you
Infographic showing various Metabolomics job openings in California as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Senior Principal Scientist: Metabolomics/Cell Therapy Media Development

Genentech, Inc.

South San Francisco, CA • On-site

$143K - $266K/yr

Full-time

Re-posted 9 days ago

Genentech rating

8.8

Company rating: 8.8 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

11th of 86 rated pharmaceutical

Job description

This role is a vital part of our Cell Therapy Process Development team within Pharma Technical Cell and Gene Therapy Development (PTCC), which is committed to advancing next-generation cell therapies through innovative metabolomics research and media optimization.
As a member of this team, you will lead cutting-edge efforts to develop and optimize cell culture media platforms while collaborating closely with key stakeholders across Analytical Development, Research, Manufacturing Operations, and cross-functional teams within Genentech and Roche. You will serve as the primary in-house expert on state-of-the-art cell therapy media development practices, translating deep scientific expertise into strategic innovations that enable breakthrough therapies to reach patients. This position offers the opportunity to shape the future of cell therapy manufacturing while fostering a collaborative, inclusive team culture focused on continuous improvement.
The Opportunity
In this role, you will lead metabolomics research initiatives focused on developing and optimizing cell culture media for a diverse portfolio of cell therapy products. You will provide scientific and strategic guidance to establish highly-productive platform processes while serving as the primary technical expert and thought leader in cell therapy media development. Additional responsibilities include:
  • Designing and developing chemically-defined cell culture media platforms tailored to meet the unique needs of T cell therapies, stem cell therapies, and other cell-based products
  • Applying advanced metabolomics tools, computational methods, and -omics technologies to deeply understand cell metabolism and drive continuous improvement in cell culture performance
  • Leading technology transfer initiatives and collaborate with manufacturing operations to translate laboratory innovations into scalable, robust processes
  • Providing technical leadership and strategic guidance to process development teams, media preparation operations, and supply chain partners to resolve complex challenges and optimize raw material selection
  • Mentoring and developing scientific staff within the Cell Therapy Process Development group, fostering a culture of technical excellence, lean thinking, and continuous improvement
  • Interfacing effectively across multiple internal stakeholder groups (Analytical Development, Research, Manufacturing, Quality) and external collaborators to align priorities and drive impactful outcomes
  • Establishing thought leadership through peer-reviewed publications, conference presentations, and participation in industry discussions on metabolomics and cell therapy manufacturing

This position may be based out of South San Francisco or San Diego, CA.
Who You Are
The successful candidate will have an established track record for strong technical leadership in metabolomics research and/or cell culture media development.
  • Advanced degree and extensive experience: PhD in biological sciences, chemical engineering, or related discipline with 5+ years of relevant research and development experience in metabolomics and/or cell culture media development
  • Strategic technical leadership: Proven track record of leading complex technical projects from conception to completion with strong organizational skills and scientific rigor; demonstrated ability to translate research insights into practical manufacturing solutions
  • Team development and inclusive leadership: Demonstrated success building, managing, and developing highly productive technical teams with an emphasis on creating an inclusive environment that values diverse perspectives and fosters collaboration
  • Matrixed stakeholder management: Proven ability to build and maintain strong relationships with cross-functional partners, customers, and collaborators; excellent skills in influencing, communication, and working effectively across organizational boundaries in complex matrixed environments
  • Thought leadership and communication: Established track record of excellent verbal and written communication demonstrated through peer-reviewed publications, conference presentations, and ability to articulate complex scientific concepts to audiences at all levels

The expected salary range for this position based on the primary location of California is $143,290 - $266,110. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at this link.
Relocation benefits are available for this position.
#LI-CA1
#ptcareers
#cellandgenetherapycareers#
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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About Genentech

Sourced by ZipRecruiter

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

South San Francisco, CA, US

Year founded

1976

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