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Metabolic Engineering Jobs in Boston, MA (NOW HIRING)

Biosens8

Bioinformatician

Cambridge, MA · On-site

$60 - $80/hr

Proficiency in programming languages commonly used in bioinformatics, such as Python, R, and Perl ... metabolic pathway analysis (e.g., BLAST, HMMER, Pfam, PDB, KEGG). Experience with designing ...

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Metabolic Engineering information

See Boston, MA salary details

$33.2K

$98.9K

$180.4K

How much do metabolic engineering jobs pay per year?

As of Sep 7, 2026, the average yearly pay for metabolic engineering in Boston, MA is $98,877.00, according to ZipRecruiter salary data. Most workers in this role earn between $61,553.00 and $128,995.00 per year, depending on experience, location, and employer.

What is metabolic engineering?

A Metabolic Engineering job involves modifying and optimizing the metabolic pathways of microorganisms or cells to improve the production of valuable chemicals, biofuels, pharmaceuticals, or other bioproducts. Professionals in this field use synthetic biology, genetic engineering, and computational modeling to enhance biological systems for industrial or medical applications. They work in biotechnology companies, research institutions, or pharmaceutical firms, often collaborating with biologists, chemists, and engineers.

What are the key skills and qualifications needed to thrive in metabolic engineering?

To thrive in Metabolic Engineering, you need a solid background in biochemistry, molecular biology, and genetic engineering, typically supported by an advanced degree in a related field. Familiarity with analytical instruments (HPLC, GC-MS), laboratory automation systems, and software for metabolic modeling (such as MATLAB or COBRA Toolbox) is highly beneficial. Strong problem-solving abilities, teamwork, and excellent communication help in effectively collaborating and translating scientific findings into practical applications. These combined skills are essential for driving innovative research and successful project outcomes in a multidisciplinary environment.

What are some common challenges faced by metabolic engineers in their daily work?

Metabolic engineers often encounter challenges such as optimizing microbial strains for desired product yield, troubleshooting unexpected metabolic bottlenecks, and adapting experiments in response to variable biological systems. Balancing benchwork with data analysis and documentation requires strong organizational skills and attention to detail. Working closely with teams in synthetic biology, fermentation, and process optimization is common, so communication and collaboration are key. Addressing these challenges is a core part of the role and provides valuable hands-on experience while fostering professional growth in the field.

What are popular job titles related to Metabolic Engineering jobs in Boston, MA?

For Metabolic Engineering jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Metabolic Engineering jobs in Boston, MA look for?

The top searched job categories for Metabolic Engineering jobs in Boston, MA are:

Metabolic Engineering jobs near you
Infographic showing various Metabolic Engineering job openings in Boston, MA as of August 2026, with employment types broken down into 89% Full Time, 6% Part Time, 4% Contract, and 1% Nights. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $98,877 per year, or $47.5 per hour.

Scientist/Senior Scientist, Drug Discovery for Neuroscience

先声药业

Cambridge, MA • On-site

$100K - $136K/yr

Other

Re-posted 9 days ago

Job description

About Simcere:

Simcere Pharmaceutical Group is an innovation-driven pharmaceutical company committed to "For patience, for life." Our core therapeutic areas include oncology, central nervous system (CNS) disorders, and autoimmune diseases. We are continuously expanding into areas with significant unmet medical needs. Our Cambridge, MA site is dedicated to cutting-edge research aligned with the company strategic directions.


Job Summary:

We are seeking a highly motivated PhD-level in-lab researcher to join our dynamic Neuroscience Discovery team. This role focuses on investigating cellular mechanisms underlying Alzheimer’s disease, Parkinson’s disease, Stroke, Pain, Psychiatric diseases and other CNS disorders. The successful candidate will develop and execute translational research to identify disease-relevant targets and develop therapeutic candidates with enhanced CNS delivery.

The ideal candidate will have hands on experience developing and testing therapeutic candidates in vitro and in vivo. This position requires an independent bench scientist and strategic thinker who can integrate therapeutic evaluation with functional disease biology. It offers a unique opportunity to contribute to impactful discoveries in a highly collaborative and innovative environment.


Responsibilities:

  • Lead target discovery efforts by identifying and validating novel therapeutic candidates for CNS diseases.
  • Advance innovation in CNS delivery, including the design, engineering, and validation of antibody‑based blood-brain barrier shuttle technologies.
  • Drive target identification and validation across CNS, psychiatric, or metabolic disorders, leveraging expertise in lipid dysmetabolism, neuroinflammation, synaptic plasticity, or vascular impairment.
  • Design and execute in vitro and/or in vivo studies to validate therapeutic targets and assess target engagement, mechanism of action, and therapeutic efficacy.
  • Analyze and interpret complex experimental data, troubleshoot technical challenges, and ensure scientific rigor across all research activities.
  • Stay abreast of emerging literature and technologies, contributing to strategic planning, and project development.


Qualifications:

  • Ph.D. in Neuroscience, Molecular Biology, Biochemistry, or a related field, with a minimum of 4 years of post-doctoral or industry experience in drug discovery.
  • Demonstrated expertise in CNS disease biology, with hands‑on experience using relevant cellular and animal models.
  • Familiarity with brain delivery strategies and platform technologies, including antibody‑based BBB shuttles or other CNS targeting modalities is preferred.
  • Experience in CNS, psychiatric, metabolic, or cardiovascular disorders, with a deep understanding of disease mechanisms and key cellular pathways.
  • Proficiency in cellular function analysis, including microscopy, flow cytometry, biochemical assays, and quantitative readouts.
  • Experience applying bioinformatics approaches (transcriptomics, proteomics, or other high‑dimensional datasets) for target identification, mechanism‑of‑action studies, or pathway analysis is highly valued.
  • Expertise in protein/antibody engineering, bioconjugation technologies, and/or AOC development.
  • A track record of impactful contributions to drug discovery programs.


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