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Medicinal Chemistry Jobs (NOW HIRING)

Medicinal Chemist

New York, NY · On-site

$210K - $250K/yr

Inductive Bio is an AI medicinal chemistry partner .We build virtual labs that help drug discovery teams make better decisions, faster, across the full DMTA cycle. Our platform includes Beacon-1 ...

Vertex is seeking a Director, Medicinal Chemistry to provide people management and strategic leadership for small-molecule discovery programs and to help advance compounds from early discovery ...

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Medicinal Chemistry information

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$81K

$143.8K

$194.5K

How much do medicinal chemistry jobs pay per year?

As of Sep 8, 2026, the average yearly pay for medicinal chemistry in the United States is $143,750.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,000.00 and $175,000.00 per year, depending on experience, location, and employer.

What is medicinal chemistry?

Medicinal chemistry is a branch of chemistry that focuses on developing pharmaceutical drugs. Professionals in this field often research chemicals, apply the principles of biology and biochemistry when synthesizing new chemicals, explore treatment options, analyze disease samples, and otherwise work to support the health of the general public. Most medicinal chemistry takes place in research labs, but drug candidates that get far enough in the development process may go through testing outside the development lab. Medicinal chemists often participate in these trials to monitor effects and provide care as needed. You can find most medicinal chemistry jobs with pharmaceutical companies, but a few jobs exist with government regulatory agencies.

What is medicinal chemistry?

Medicinal chemistry is a scientific discipline at the intersection of chemistry, pharmacology, and biology. It involves the design, synthesis, and development of chemical compounds that can be used as pharmaceutical agents to prevent, treat, or cure diseases. Medicinal chemists analyze the structure-activity relationships of molecules to optimize their efficacy, safety, and pharmacokinetic properties. The field plays a crucial role in drug discovery and development, collaborating closely with biologists, pharmacologists, and other scientists.

What are the key skills and qualifications needed to thrive as a medicinal chemist, and why are they important?

To thrive as a Medicinal Chemist, you need a strong background in organic and analytical chemistry, typically supported by a Ph.D. or master's degree in chemistry or a related field. Familiarity with techniques such as NMR, mass spectrometry, and chromatography, as well as experience with chemical informatics software, are essential. Attention to detail, problem-solving abilities, and effective teamwork are standout soft skills for this role. These skills and qualifications are crucial for designing and optimizing drug candidates efficiently, ensuring scientific rigor, and collaborating successfully in multidisciplinary research environments.

What are some common challenges medicinal chemists face when working on drug discovery projects?

Medicinal chemists often encounter challenges such as optimizing the balance between a compound’s potency, selectivity, and pharmacokinetic properties. This process requires significant collaboration with biologists, pharmacologists, and analytical chemists to iteratively refine molecules for effectiveness and safety. Additionally, deadlines can be tight due to project milestones and funding cycles, making time management and adaptability crucial. Working in multidisciplinary teams also means strong communication skills are vital to ensure everyone is aligned on project goals and progress.

What is the difference between Medicinal Chemistry vs Organic Chemistry?

AspectMedicinal ChemistryOrganic Chemistry
Required CredentialsBachelor's or Master's in Chemistry, PhD often preferredBachelor's or Master's in Chemistry, PhD often preferred
Work EnvironmentPharmaceutical labs, research institutionsAcademic labs, research institutions, industry
Industry UsageDrug development, pharmaceutical researchMaterials, polymers, natural products, academic research
Common Search/ComparisonMedicinal Chemistry vs Organic Chemistry

Medicinal Chemistry focuses on designing and developing new drugs, often working closely with pharmacology and biology. Organic Chemistry involves studying the structure, properties, and reactions of organic compounds, with broader applications in materials and academia. While both fields require strong chemistry backgrounds, Medicinal Chemistry is more specialized towards pharmaceuticals, whereas Organic Chemistry covers a wider range of chemical research areas.

How much money do medicinal chemists make?

Medicinal chemists typically earn a median annual salary of around $80,000 to $120,000, depending on experience, education, and location. Senior professionals with advanced degrees and specialized skills can earn higher salaries, often exceeding $150,000. Salaries may also vary based on industry sector and company size.

What can I do with a medicinal chemistry degree?

A medicinal chemistry degree prepares individuals for roles in drug discovery, development, and research within pharmaceutical companies, biotech firms, or academic institutions. Graduates often work as medicinal chemists, research scientists, or formulation specialists, utilizing skills in chemical synthesis, analysis, and laboratory techniques. Advanced positions may require additional experience or certifications in related fields such as pharmacology or toxicology.

What careers are in medicinal chemistry?

Careers in medicinal chemistry include roles such as medicinal chemist, pharmaceutical researcher, drug discovery scientist, and formulation scientist. These professionals typically work in pharmaceutical companies, research institutions, or biotech firms, utilizing skills in organic chemistry, pharmacology, and laboratory techniques to develop new medications.

What cities are hiring for Medicinal Chemistry jobs?

Cities with the most Medicinal Chemistry job openings:

What are the most commonly searched types of Medicinal Chemistry jobs?

The most popular types of Medicinal Chemistry jobs are:

What states have the most Medicinal Chemistry jobs?

States with the most job openings for Medicinal Chemistry jobs include:

Infographic showing various Medicinal Chemistry job openings in the United States as of September 2026, with employment types broken down into 86% Full Time, and 14% Part Time. Highlights an 100% In-person job distribution, with an average salary of $143,750 per year, or $69.1 per hour.

Head of Medicinal Chemistry

Natick, MA • On-site

Allorion Therapeutics
Pharmaceutical and Medicine Manufacturing • 11 - 50 employees

Full-time

Re-posted 27 days ago


Job description

Natick, Massachusetts
Position closed
Allorion Therapeutics is seeking a highly motivated and experienced leader as Head of Medicinal Chemistry to lead medicinal chemistry team within a dynamic and interdisciplinary team of junior or senior scientists to develop new therapeutics for unmet medical needs. The successful candidate will be a key member of the Allorion leadership team and responsible for ensuring the strategic planning and execution of clinical development within timelines and budgets and with high qualities.
Responsibilities
  • Lead Allorion medicinal chemistry team across multiple programs
  • Overview all programs up to IND-enabling studies, including structure-based drug design
  • Provide scientific direction, leadership and solution for medicinal chemistry and synthetic
    chemistry activities of Allorion
  • Work across a matrixed organization with Discovery Biology, Translational Medicine,
    DMPK/clinic pharm, Tox, and CMC to deliver the candidate compound within a suitable timeline
  • Provide strategic perspective and guidance to Allorion's R&D for discussions and decisions with
    Allorion management team
  • Overview synthetic chemistry activities at in-house and Contract Research Organizations (CROs)

Required Skills
  • PhD with strong chemistry research background
  • 15+ years of industry experience with 5+ years in leading medicinal chemistry group, with
    demonstrated track records in delivering clinical candidates within a suitable timeline and
    resource
  • Able to provide leadership on a medicinal chemistry team and cross-functional team
  • Strong organizational skills and the ability to manage multiple tasks
  • Ability to thrive in the highly entrepreneurial biotech environment, with experience in a
    small/medium size company
  • Excellent interpersonal skills and mindset of collaboration and teamwork, and the ability to
    function in a highly matrixed organization

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