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Mass Spectrometry Jobs in Raleigh, NC (NOW HIRING)

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SR ANALYTICAL SCIENTIST

Durham, NC · On-site

This individual will be responsible for developing methodology and performing advanced product quality characterization techniques primarily with Gas Chromatography/Mass Spectrometry (GC/MS)

RTI International

PFAS Laboratory Manager

Durham, NC · On-site

Using advanced LC-MS/MS and high-resolution mass spectrometry platforms, we analyze PFAS in a wide range of environmental and biological matrices, develop and validate innovative analytical methods ...

RTI International

PFAS Laboratory Manager

Durham, NC · On-site

Using advanced LC-MS/MS and high-resolution mass spectrometry platforms, we analyze PFAS in a wide range of environmental and biological matrices, develop and validate innovative analytical methods ...

NCSU

Research Scholar, Metabolomics

Raleigh, NC

Mass spectrometry: small molecule identification and structural analysis, targeted and untargeted metabolomics, proteomics, lipidomics, MS imaging. * NMR spectroscopy: small molecule and ...

RTI International

PFAS Laboratory Manager

Durham, NC

Using advanced LC-MS/MS and high-resolution mass spectrometry platforms, we analyze PFAS in a wide range of environmental and biological matrices, develop and validate innovative analytical methods ...

RTI International

PFAS Laboratory Manager

Durham, NC

Using advanced LC-MS/MS and high-resolution mass spectrometry platforms, we analyze PFAS in a wide range of environmental and biological matrices, develop and validate innovative analytical methods ...

Pace

Principal Scientist- NMR Spectroscopy

Morrisville, NC · On-site

$110K - $120K/yr

Working knowledge of chromatography, mass spectrometry, and other characterization techniques to support orthogonal testing. * Understanding of laboratory quality systems, data integrity principles ...

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How much do mass spectrometry jobs pay per hour?

As of Jul 30, 2026, the average hourly pay for mass spectrometry in Raleigh, NC is $21.99, according to ZipRecruiter salary data. Most workers in this role earn between $17.98 and $23.37 per hour, depending on experience, location, and employer.

What is a Mass Spectrometry job?

A Mass Spectrometry job involves using mass spectrometers to analyze the composition of chemical or biological samples. Professionals in this field work in industries such as pharmaceuticals, environmental science, forensics, and biotechnology. Their responsibilities include sample preparation, instrument calibration, data interpretation, and reporting findings. These roles require expertise in analytical chemistry, laboratory techniques, and data analysis software.

What are the key skills and qualifications needed to thrive in the Mass Spectrometry position, and why are they important?

To thrive in Mass Spectrometry, you need a strong background in analytical chemistry or biochemistry, experience operating mass spectrometry instruments, and a relevant degree such as a B.Sc., M.Sc., or Ph.D. in a related field. Familiarity with laboratory information management systems (LIMS), chromatography software, and certifications such as ASMS or relevant lab safety training is also highly valued. Attention to detail, problem-solving ability, and effective communication skills distinguish top performers. These skills ensure accurate data generation, effective troubleshooting, and smooth collaboration with research teams or clients.

What are the typical daily responsibilities of a professional working in Mass Spectrometry?

Professionals working in Mass Spectrometry are responsible for preparing and analyzing samples, calibrating and maintaining instruments, and interpreting complex analytical data. They often work closely with other scientists, research associates, or quality control teams to support research, development, or quality assurance projects. Documenting procedures and results accurately is crucial, as is troubleshooting equipment or methodology when challenges arise. Additionally, they may participate in method development or validation, contributing to process optimization and innovation within their organization.

What are the most commonly searched types of Mass Spectrometry jobs in Raleigh, NC? The most popular types of Mass Spectrometry jobs in Raleigh, NC are:
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Mass Spectrometry jobs near you
Infographic showing various Mass Spectrometry job openings in Raleigh, NC as of July 2026, with employment types broken down into 82% Full Time, 17% Part Time, and 1% Contract. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $45,734 per year, or $22 per hour.

Senior Research Scholar - Mass Spectrometry Metabolomics

NCSU

Raleigh, NC

Other

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 5 days ago

North Carolina State University rating

6.8

Company rating: 6.8 out of 10

Based on 33 frontline employees who took The Breakroom Quiz

455th of 613 rated colleges and universities

Job description

Posting Information
Posting Number PG193454EP Internal Recruitment No Working Title Senior Research Scholar - Mass Spectrometry Metabolomics Anticipated Hiring Range $85,000 - $107,573 (commensurate with education and experience) Work Schedule 8:00 AM - 5:00 PM, Monday-Friday Job Location Raleigh, NC Department METRIC Mass Spectrometry Platform Technology About the Department
The overarching goal of the Molecular Education, Technology and Research Innovation Center (METRIC) is to offer clients seamless access to qualitative and quantitative analysis for a diverse range of molecules, supporting research across multiple platform technologies and molecular scales. By coordinating three key platform technologies (Mass Spectrometry, NMR spectroscopy and X-ray crystallography), METRIC provides an integrated, measurement science facility that fosters research and collaboration throughout the greater university community. METRIC provides researchers access to the following services:
  • Mass spectrometry: small molecule identification and structural analysis, targeted and untargeted metabolomics, proteomics, lipidomics, MS imaging.
  • NMR spectroscopy: small molecule and macromolecular solution structures, protein-ligand interactions, protein dynamics.
  • X-ray crystallography: small molecule and macromolecular crystal structure determination.
  • Education, training and outreach: METRIC offers training to new users, enhances graduate and undergraduate education through providing formal instruction, organizing educational materials, short courses and workshops to support users, maintaining protocols for routine sample handling, and hosting regular forums for users to interact and share new methods.
Wolfpack Perks and Benefits
As a Pack member, you belong here, and can enjoy exclusive perks designed to enhance your personal and professional well-being.

What we offer:
  • Medical, Dental, and Vision
  • Flexible Spending Account
  • Retirement Programs
  • Disability Plans
  • Life Insurance
  • Accident Plan
  • Paid Time Off and Other Leave Programs
  • 12 Holidays Each Year
  • Tuition and Academic Assistance
  • And so much more!
Attain Work-life balance with our Childcare benefits, Wellness & Recreation Membership, and Wellness Programs that aim to build a thriving wolfpack community. 
Disclaimer: Perks and Benefit eligibility is based on Part-Time or Full-Time Employment status. Eligibility and Employer Sponsored Plans can be found within each of the links offered.
Essential Job Duties
Duties include, but are not limited to:
1. Experimental Consultation and Design:
  • Serve as the point of contact for client inquiries in the area of small molecule analysis by targeted and untargeted metabolomics, including lipidomics.
  • Provide expert advice on experimental design, including selection of sample preparation techniques and analytical methods, to ensure methodological rigor and feasibility.
  • Collaborate with other staff members to develop and optimize metabolomics experimental protocols.
  • Stay abreast of the latest advances in analytical methods and techniques to integrate into research projects.

2. Sample Preparation and Acquisition:
  • Perform liquid, liquid-liquid, or SPE extraction, derivatization, and other pre-analytical steps to ensure sample integrity and suitability for downstream analysis.
  • Operate and maintain LC-MS metabolomics instrumentation (e.g. Thermo TSQ Altis Triple Quadrupole, Exploris 240, Exploris 480, ID-X).
  • Develop and implement standard operating procedures (SOPs) for sample handling and preparation to ensure consistency across studies.

3. Data Analysis and Interpretation:
  • Perform metabolomics studies and report the results (analyte peak area or concentrations) using relevant software such as Skyline, MS-Dial, and Compound Discoverer.
  • Use appropriate statistical and bioinformatics tools to extract meaningful biological insights.
  • Perform pathway analysis using specialized software and databases, as needed.
  • Interpret complex datasets and collaborate with researchers to contextualize findings within the scope of the project.
  • Prepare detailed reports and visualizations of data for internal review, publication in scientific journals, and use in grant applications.

4. Administrative Responsibilities:
  • Maintain accurate and up-to-date laboratory records, including experimental protocols, data logs, and inventory of samples and reagents.
  • Coordinate with the operations manager to ensure adequate supplies; ensure continuity of operations by coordinating maintenance of major instrumentation and associated ancillary equipment.
  • Assist in the training and supervision of staff and students in metabolomics techniques and best practices.
  • Contribute to the preparation of manuscripts, grant applications, and progress reports for funding agencies.
  • Ensure compliance with institutional and regulatory requirements related to biosafety, data management, and ethical standards.

Additional duties as assigned based on institutional needs and priorities.
Other Responsibilities
Other duties as assigned.
Qualifications
Minimum Education and Experience
  • Ph.D. in a relevant field, with at least five years of experience in metabolomics research methods and/or post-degree professional work experience with a demonstrated record of research achievement.
OR
  • Relevant Master's degree, plus at least 8 years of exceptional relevant professional work experience and a record of research achievements.
OR
  • In rare instances, an individual with comparable professional experience but less than a master's degree will be considered, on an exception basis. May require terminal degree and licensure.
Other Required Qualifications
  • Significant experience in untargeted and targeted metabolomics, advanced separations, tandem MS, absolute quantification, IROA, credentialing, bioinformatics, and metabolome databases.
  • Demonstrated ability to develop workflows and standard operating procedures (SOPs).
  • Must possess exceptional communication skills, including written and verbal, be highly organized and detail-oriented.
  • Must be able to work independently, use initiative, prioritize tasks, and anticipate potential pressure points in workflows.
  • Ability to develop and maintain productive collaborative work relationships with all clients by listening, understanding and responding to apparent and underlying needs and continually seeking to provide the highest quality service to all.
Preferred Qualifications
  • Prefer experience with lipidomics and/or mass spectrometry-based imaging.
  • Prefer experience with integrating data from multiple-omics based approaches.
Required License(s) or Certification(s)
N/A
Valid NC Driver's License required No Commercial Driver's License required No
Recruitment Dates and Special Instructions
Job Open Date 06/01/2025 Anticipated Close Date Open Until Filled Special Instructions to Applicants
Please attach resume, cover letter, and contact information for three professional references.
Email inquires should be sent to Joe Barycki, Director, METRIC, at joe_barycki@ncsu.edu
Position Details
Position Number 00050194 Position Type Exempt Professional Staff Full Time Equivalent (FTE) (1.0 = 40 hours/week) 1.00 Appointment 12 Month Recurring Mandatory Designation - Adverse Weather Non Mandatory - Adverse Weather Mandatory Designation - Emergency Events Non Mandatory - Emergency Event Department ID 210204 - METRIC Mass Spectrometry Platform Technology EEO
NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-515-3148 to speak with a representative at the Office of Institutional Equity and Diversity.
If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.
NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.

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About North Carolina State University

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North Carolina State University (NCSU), located in Raleigh, NC, US, is a leading educational institution with a strong emphasis on research, academics, and public service. Established in 1887, NCSU operates in the education industry and endeavors to foster student success, and promote economic development by providing high-quality, affordable education, and conducting groundbreaking research across a variety of disciplines. With more than 100 majors, its academic offerings range from undergraduates to postgraduates along with doctoral studies - in various fields like engineering, natural resources, humanities, and social sciences. NCSU is firmly anchored on the core values of respect, responsibility, integrity, and innovation. Its mission is to create economic, societal, and intellectual prosperity for the people of North Carolina and the nation.

Industry

Colleges, universities, and professional schools

Company size

5,001 - 10,000 Employees

Headquarters location

Raleigh, NC, US

Year founded

1887

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