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Machine Learning Engineer Biotech Jobs in Chicago, IL

Must-Have Skills 3+ years of ML engineering experience -- model training, fine-tuning, or post-training pipelines in research or production Strong Python and deep learning proficiency (PyTorch ...

Must-Have Skills 3+ years of ML engineering experience -- model training, fine-tuning, or post-training pipelines in research or production Strong Python and deep learning proficiency (PyTorch ...

Must-Have Skills 3+ years of ML engineering experience -- model training, fine-tuning, or post-training pipelines in research or production Strong Python and deep learning proficiency (PyTorch ...

Must-Have Skills 3+ years of ML engineering experience -- model training, fine-tuning, or post-training pipelines in research or production Strong Python and deep learning proficiency (PyTorch ...

Must-Have Skills 3+ years of ML engineering experience -- model training, fine-tuning, or post-training pipelines in research or production Strong Python and deep learning proficiency (PyTorch ...

Senior Machine Learning Engineer (Nova)

Chicago, IL · On-site

$107K - $147K/yr

They are seeking a Senior Machine Learning Engineer to build core Machine Learning foundations, focusing on applied Machine Learning in production environments, and collaborating with various teams ...

Machine Learning Engineer

Chicago, IL · Remote

$96K - $131K/yr

Develop and implement analytics techniques to transform data into meaningful information using data-oriented programming languages, visualization software, data modeling, and machine learning to ...

We're looking for a Principal Machine Learning Engineer to help shape the next phase of our platform - influencing architecture, driving best practices, and solving high-leverage problems. You'll ...

AI Machine Learning Engineer

Chicago, IL · Hybrid

$100K - $151K/yr

The Hartford is seeking AI Machine Learning Engineer to build Machine Learning Operations (MLOps) services for the Global Specialty Applied AI team. The Hartford is developing industryleading AI and ...

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Machine Learning Engineer Biotech information

See Chicago, IL salary details

$32.5K

$132.7K

$199.3K

How much do machine learning engineer biotech jobs pay per year?

As of Jul 3, 2026, the average yearly pay for machine learning engineer biotech in Chicago, IL is $132,651.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,600.00 and $159,700.00 per year, depending on experience, location, and employer.

What does a Machine Learning Engineer do in the biotech industry?

A Machine Learning Engineer in biotech applies advanced algorithms and data analysis techniques to solve biological and medical problems. They work with large datasets such as genomic sequences, medical images, or clinical records to develop predictive models, automate data analysis, and uncover insights that can accelerate drug discovery, diagnostics, and personalized medicine. Their work often involves close collaboration with biologists, data scientists, and software engineers to create tools and solutions that improve healthcare outcomes. Machine Learning Engineers in this field need a strong background in both computational methods and biological sciences.

How do Machine Learning Engineers in biotech typically collaborate with research scientists and domain experts?

Machine Learning Engineers in biotech often work closely with research scientists and domain experts to translate complex biological problems into data-driven solutions. This collaboration involves regular meetings to understand experimental data, refine project goals, and iterate on model development based on domain feedback. Engineers are expected to communicate technical concepts clearly, adapt models to fit scientific needs, and help validate results alongside laboratory teams. This interdisciplinary environment fosters innovation but also requires flexibility and strong communication skills.

What are the key skills and qualifications needed to thrive as a Machine Learning Engineer in Biotech, and why are they important?

To thrive as a Machine Learning Engineer in Biotech, you need a solid background in computer science, statistics, and biology, often with an advanced degree in a related field. Experience with programming languages such as Python or R, machine learning frameworks like TensorFlow or PyTorch, and familiarity with bioinformatics tools are typically required. Strong problem-solving, communication, and interdisciplinary collaboration skills set standout candidates apart. These capabilities are crucial for developing effective models that drive scientific innovation and advance biotechnological research.

What is the difference between Machine Learning Engineer Biotech vs Data Scientist Biotech?

AspectMachine Learning Engineer BiotechData Scientist Biotech
Required CredentialsBachelor's or Master's in Computer Science, Data Science, or related; knowledge of ML frameworksBachelor's or Master's in Data Science, Statistics, or related; strong analytical skills
Work EnvironmentDevelops ML models, coding, deploying algorithms in biotech R&DAnalyzes biological data, interprets results, creates reports
Employer & Industry UsageBiotech firms, pharma companies, research labsBiotech companies, healthcare, research institutions

While both roles work with biological data, Machine Learning Engineers focus on developing and deploying ML algorithms, whereas Data Scientists analyze and interpret biological datasets to inform research and decision-making in biotech settings.

What are the most commonly searched types of Machine Learning Engineer Biotech jobs in Chicago, IL? The most popular types of Machine Learning Engineer Biotech jobs in Chicago, IL are:
What job categories do people searching Machine Learning Engineer Biotech jobs in Chicago, IL look for? The top searched job categories for Machine Learning Engineer Biotech jobs in Chicago, IL are:
What cities near Chicago, IL are hiring for Machine Learning Engineer Biotech jobs? Cities near Chicago, IL with the most Machine Learning Engineer Biotech job openings:
Infographic showing various Machine Learning Engineer Biotech job openings in Chicago, IL as of June 2026, with employment types broken down into 64% Full Time, and 36% Contract. Highlights an 100% In-person job distribution, with an average salary of $132,651 per year, or $63.8 per hour.

Full-time

Posted 16 days ago


Job description

About Us

We are AI researchers and builders who understand how to curate data and RL environments that truly improve models. We curated OpenThoughts, one of the best open reasoning datasets, and have trained SOTA models such as Bespoke-MiniCheck and Bespoke-MiniChart.

We are embarked on a journey to build Environments that are entire digital worlds that can be used to push the frontier of agents.

What You'll Be Working On

You will work directly with our research team on RL environment and task creation for agent training. This means designing observation spaces, action spaces, reward signals, and success criteria for new environments — and building the infrastructure that makes world-scale RL training possible. This is a high-ownership role; you will be building novel systems, not maintaining legacy ones.

Must-Have Skills

3+ years of ML engineering experience — model training, fine-tuning, or post-training pipelines in research or production

Strong Python and deep learning proficiency (PyTorch preferred; familiar with training loops, optimizers, mixed precision)

Hands-on experience with LLM post-training — SFT, RLHF, PPO, DPO, or reward model training — and understanding of how training data quality affects model behavior

Familiarity with RL frameworks (Gymnasium, dm_env) and the ability to design or modify reward functions for agent training objectives

Experience running experiments at scale on cloud or HPC (AWS, GCP, SLURM, or Ray)

Solid understanding of evaluation methodology — held-out sets, benchmark design, avoiding train/eval contamination